| Literature DB >> 25020256 |
Taishi Kusama1, Naonobu Tanaka, Kanae Sakai, Tohru Gonoi, Jane Fromont, Yoshiki Kashiwada, Jun'ichi Kobayashi.
Abstract
Two structurally unique dimeric bromopyrrole alkaloids, agelamadins A (1) and B (2), were isolated from a marine sponge Agelas sp. Agelamadins A (1) and B (2) have a structure consisting of an agelastatin-like tetracyclic moiety and an oroidin-like linear moiety in common. The structures of 1 and 2 were elucidated on the basis of spectroscopic analysis. The antimicrobial activity and cytotoxicity of agelamadins A (1) and B (2) were evaluated.Entities:
Mesh：
Substances：
Year: 2014 PMID： 25020256 DOI： 10.1021/ol501664b
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005