Literature DB >> 2501662

A moveable 5' splice site in adenine phosphoribosyltransferase genes of Drosophila species.

D Johnson1, S Henikoff.   

Abstract

In two distantly related Drosophila species, the use of alternate 5' splice sites to process an intron in pre-mRNA from homologous adenine phosphoribosyltransferase (APRT)-encoding genes led to RNAs encoding nonfunctional peptides in addition to APRT. The production of aberrantly spliced transcripts as a normal feature of gene expression supports a general model of eucaryotic gene evolution through alternative splicing and moveable splice junctions.

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Year:  1989        PMID: 2501662      PMCID: PMC363017          DOI: 10.1128/mcb.9.5.2220-2223.1989

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN: 0270-7306            Impact factor:   4.272


  20 in total

1.  Tissue specificity of Drosophila P element transposition is regulated at the level of mRNA splicing.

Authors:  F A Laski; D C Rio; G M Rubin
Journal:  Cell       Date:  1986-01-17       Impact factor: 41.582

2.  Direct sequencing of amplified genomic fragments documents N-ras point mutations in myeloid leukemia.

Authors:  S J Collins
Journal:  Oncogene Res       Date:  1988-09

3.  A simple and very efficient method for generating cDNA libraries.

Authors:  U Gubler; B J Hoffman
Journal:  Gene       Date:  1983-11       Impact factor: 3.688

4.  Rapid and efficient site-specific mutagenesis without phenotypic selection.

Authors:  T A Kunkel
Journal:  Proc Natl Acad Sci U S A       Date:  1985-01       Impact factor: 11.205

5.  Splice junctions: association with variation in protein structure.

Authors:  C S Craik; W J Rutter; R Fletterick
Journal:  Science       Date:  1983-06-10       Impact factor: 47.728

6.  Unusual splice sites revealed by mutagenic inactivation of an authentic splice site of the rabbit beta-globin gene.

Authors:  B Wieringa; F Meyer; J Reiser; C Weissmann
Journal:  Nature       Date:  1983-01-06       Impact factor: 49.962

7.  Genomic sequencing.

Authors:  G M Church; W Gilbert
Journal:  Proc Natl Acad Sci U S A       Date:  1984-04       Impact factor: 11.205

8.  Why genes in pieces?

Authors:  W Gilbert
Journal:  Nature       Date:  1978-02-09       Impact factor: 49.962

9.  Nucleotide sequence and organization of the mouse adenine phosphoribosyltransferase gene: presence of a coding region common to animal and bacterial phosphoribosyltransferases that has a variable intron/exon arrangement.

Authors:  M K Dush; J M Sikela; S A Khan; J A Tischfield; P J Stambrook
Journal:  Proc Natl Acad Sci U S A       Date:  1985-05       Impact factor: 11.205

10.  Purine-resistant Drosophila melanogaster result from mutations in the adenine phosphoribosyltransferase structural gene.

Authors:  D H Johnson; T B Friedman
Journal:  Proc Natl Acad Sci U S A       Date:  1983-05       Impact factor: 11.205

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  4 in total

1.  A novel RNA helicase gene tightly linked to the Triplo-lethal locus of Drosophila.

Authors:  D R Dorer; A C Christensen; D H Johnson
Journal:  Nucleic Acids Res       Date:  1990-09-25       Impact factor: 16.971

2.  The urate oxidase gene of Drosophila pseudoobscura and Drosophila melanogaster: evolutionary changes of sequence and regulation.

Authors:  T B Friedman; J B Burnett; S Lootens; R Steinman; L L Wallrath
Journal:  J Mol Evol       Date:  1992-01       Impact factor: 2.395

3.  Adenine phosphoribosyltransferase genes in two Drosophila species: dosage compensation, a nuclear matrix attachment site, and a novel intron position.

Authors:  D H Johnson
Journal:  Mol Gen Genet       Date:  1993-04

4.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1989-09-25       Impact factor: 16.971

  4 in total

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