Literature DB >> 24993967

The stimulating influence of thienopyrimidine compounds on the adenylyl cyclase signaling systems in the rat testes.

A O Shpakov1, D V Dar'in, K V Derkach, P S Lobanov.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 24993967     DOI： 10.1134/S1607672914030065

Source DB:  PubMed          Journal:  Dokl Biochem Biophys        ISSN： 1607-6729            Impact factor:   0.788


× No keyword cloud information.
  8 in total

1.  The first orally active low molecular weight agonists for the LH receptor: thienopyr(im)idines with therapeutic potential for ovulation induction.

Authors:  N C R van Straten; G G Schoonus-Gerritsma; R G van Someren; J Draaijer; A E P Adang; C M Timmers; R G J M Hanssen; C A A van Boeckel
Journal:  Chembiochem       Date:  2002-10-04       Impact factor: 3.164

2.  Determination of different putative allosteric binding pockets at the lutropin receptor by using diverse drug-like low molecular weight ligands.

Authors:  Laura H Heitman; Gunnar Kleinau; Johannes Brussee; Gerd Krause; Adriaan P Ijzerman
Journal:  Mol Cell Endocrinol       Date:  2012-01-18       Impact factor: 4.102

Review 3.  [Low-molecular regulators of polypeptide hormones receptors containing LGR repeats].

Authors:  A O Shpakov; E A Shpakova
Journal:  Biomed Khim       Date:  2010 May-Jun

4.  A signaling-selective, nanomolar potent allosteric low molecular weight agonist for the human luteinizing hormone receptor.

Authors:  Chris J van Koppen; Guido J R Zaman; C Marco Timmers; Jan Kelder; Sietse Mosselman; Ruud van de Lagemaat; Martin J Smit; Rob G J M Hanssen
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2008-06-13       Impact factor: 3.000

Review 5.  [Structural-functional organization of polypeptide hormones receptors containing LRR-repeats and their interaction with heterotrimeric G proteins].

Authors:  A O Shpakov
Journal:  Tsitologiia       Date:  2009

Review 6.  G protein-coupled receptors of the hypothalamic-pituitary-gonadal axis: a case for Gnrh, LH, FSH, and GPR54 receptor ligands.

Authors:  Laura H Heitman; Adriaan P Ijzerman
Journal:  Med Res Rev       Date:  2008-11       Impact factor: 12.944

7.  Induction of ovulation by a potent, orally active, low molecular weight agonist (Org 43553) of the luteinizing hormone receptor.

Authors:  R van de Lagemaat; C M Timmers; J Kelder; C van Koppen; S Mosselman; R G J M Hanssen
Journal:  Hum Reprod       Date:  2008-12-16       Impact factor: 6.918

Review 8.  Structure-function relationships of the luteinizing hormone receptor.

Authors:  David Puett; Yongsheng Li; Krassimira Angelova; Geneva Demars; Thomas P Meehan; Francesca Fanelli; Prema Narayan
Journal:  Ann N Y Acad Sci       Date:  2005-12       Impact factor: 5.691
  8 in total
  3 in total

1.  Intratesticular, intraperitoneal, and oral administration of thienopyrimidine derivatives increases the testosterone level in male rats.

Authors:  K V Derkach; D V Dar'in; P S Lobanov; A O Shpakov
Journal:  Dokl Biol Sci       Date:  2015-01-06

2.  The Effects of Separate and Combined Treatment of Male Rats with Type 2 Diabetes with Metformin and Orthosteric and Allosteric Agonists of Luteinizing Hormone Receptor on Steroidogenesis and Spermatogenesis.

Authors:  Andrey A Bakhtyukov; Kira V Derkach; Viktor N Sorokoumov; Anna M Stepochkina; Irina V Romanova; Irina Yu Morina; Irina O Zakharova; Liubov V Bayunova; Alexander O Shpakov
Journal:  Int J Mol Sci       Date:  2021-12-24       Impact factor: 5.923

3.  Comparative Study of the Steroidogenic Effects of Human Chorionic Gonadotropin and Thieno[2,3-D]pyrimidine-Based Allosteric Agonist of Luteinizing Hormone Receptor in Young Adult, Aging and Diabetic Male Rats.

Authors:  Andrey A Bakhtyukov; Kira V Derkach; Maxim A Gureev; Dmitry V Dar'in; Viktor N Sorokoumov; Irina V Romanova; Irina Yu Morina; Anna M Stepochkina; Alexander O Shpakov
Journal:  Int J Mol Sci       Date:  2020-10-11       Impact factor: 5.923
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.