Literature DB >> 24989362

Strategies to treat idiopathic granulomatous mastitis: retrospective analysis of 40 patients.

Tuba Atak1, Jülide Sagiroglu1, Tunc Eren1, Ibrahim Ali Özemir1, Orhan Alimoglu1.   

Abstract

BACKGROUND: Idiopathic granulomatous mastitis (IGM) is a rare benign breast disease which often mimics breast carcinoma both clinically and radiologically. Confirmation of diagnosis is only made by histopathological analysis. This study aims to define clinical and demographic features of IGM patients and discuss the results of treatment modalities.
METHODS: Forty patients with IGM who were assigned in Istanbul Medeniyet University General Surgery Clinic between March 2008 and October 2013 were retrospectively analyzed.
RESULTS: Mean age was 39.07 ± 11.5. The most common complaint was breast mass (55%). Nipple retraction was present in 6 patients (15%) and 9 patients (22.5%) had fistulizing abscess. Two patients had erythema nodosum on the lower extremity. Breast ultrasonography (USG) (n:40), mammography (MG) (n:20), and magnetic resonance imaging (MRI) (n:20) were used for imaging. Selected treatment methods were antibiotics and anti-inflammatory agents (27.5%), steroids (15%), abscess drainage (40%), and surgical excision (17.5%). Fifteen patients had recurrence after their first line treatment protocol. Mean follow-up period was 24.85 ± 19.7 months.
CONCLUSION: Surgical excision still seems to be the best treatment method for IGM patients. Administration of steroids for large lesions prior to surgery may help minimize the lesion size and obtain better cosmesis.

Entities:  

Keywords:  Idiopathic; granulomatous mastitis; treatment strategies

Mesh:

Substances:

Year:  2015        PMID: 24989362     DOI: 10.3233/BD-140373

Source DB:  PubMed          Journal:  Breast Dis        ISSN: 0888-6008


  11 in total

1.  Topical Steroids Are Effective in the Treatment of Idiopathic Granulomatous Mastitis.

Authors:  Fatih Altintoprak; Taner Kivilcim; Omer Yalkin; Yener Uzunoglu; Zeynep Kahyaoglu; Osman Nuri Dilek
Journal:  World J Surg       Date:  2015-11       Impact factor: 3.352

Review 2.  Idiopathic granulomatous mastitis: an inflammatory breast condition with review of the literature.

Authors:  Michelle Mathew; Portia Siwawa; Subhasis Misra
Journal:  BMJ Case Rep       Date:  2015-03-04

3.  Idiopathic granulomatous mastitis: an institutional experience.

Authors:  Seetharam Prasad; Padmapriya Jaiprakash; Aniket Dave; Deepti Pai
Journal:  Turk J Surg       Date:  2017-06-01

4.  Is There any Relationship Between Granulomatous Mastitis and Seasons? An Analysis of Seasonal Frequency, Clinical, and Radiologic Findings.

Authors:  Leyla Tekin; Funda Dinç Elibol
Journal:  Eur J Breast Health       Date:  2020-10-01

5.  Granulomatous Lobular Mastitis: Antituberculous Treatment and Outcome in 22 Patients.

Authors:  Lu Liu; Fei Zhou; Xiaoxia Zhang; Shuchen Liu; Liyuan Liu; Yujuan Xiang; Mingming Guo; Lixiang Yu; Fei Wang; Zhongbing Ma; Liang Li; Dezong Gao; Qiang Zhang; Qinye Fu; Zhigang Yu
Journal:  Breast Care (Basel)       Date:  2018-07-05       Impact factor: 2.860

6.  Idiopathic granulomatous mastitis: dilemmas in diagnosis and treatment.

Authors:  Rahim Mahmodlou; Niloofar Dadkhah; Fariba Abbasi; Jafar Nasiri; Rohollah Valizadeh
Journal:  Electron Physician       Date:  2017-09-25

7.  A Proposal of a Clinically Based Classification for Idiopathic Granulomatous Mastitis

Authors:  Rami Yaghan; Shadi Hamouri; Nehad M Ayoub; Lamees Yaghan; Tagleb Mazahreh
Journal:  Asian Pac J Cancer Prev       Date:  2019-03-26

8.  Magnetic resonance imaging findings of idiopathic granulomatous mastitis: can it be an indirect sign of treatment success or fail?

Authors:  Ayşegül Altunkeser; Fatma Zeynep Arslan; Mehmet Ali Eryılmaz
Journal:  BMC Med Imaging       Date:  2019-12-16       Impact factor: 1.930

Review 9.  Comparison of Conservative versus Surgical Treatment Protocols in Treating Idiopathic Granulomatous Mastitis: A Meta-Analysis.

Authors:  Fei Zhou; Lu Liu; Liyuan Liu; Lixiang Yu; Fei Wang; Yujuan Xiang; Chao Zheng; Shuya Huang; Han Cai; Zhigang Yu
Journal:  Breast Care (Basel)       Date:  2019-10-22       Impact factor: 2.860

10.  The Role of Establishing a Multidisciplinary Team for Idiopathic Granulomatous Mastitis in Improving Patient Outcomes and Spreading Awareness about Recent Disease Trends.

Authors:  Rami J Yaghan; Nehad M Ayoub; Shadi Hamouri; Alia Al-Mohtaseb; Maha Gharaibeh; Lamees Yaghan; Mahmoud Al-Dari; Hiba Al-Kaff; Nabil A Al-Zoubi
Journal:  Int J Breast Cancer       Date:  2020-01-27
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