Fatih Altintoprak1, Taner Kivilcim2, Omer Yalkin2, Yener Uzunoglu2, Zeynep Kahyaoglu3, Osman Nuri Dilek4,5. 1. Department of General Surgery, Faculty of Medicine, Sakarya University, Sakarya, Turkey. fatihaltintoprak@yahoo.com. 2. Department of General Surgery, Research and Educational Hospital, Sakarya University, Sakarya, Turkey. 3. Department of Pathology, Research and Educational Hospital, Sakarya University, Sakarya, Turkey. 4. Department of General Surgery, Faculty of Medicine, Sakarya University, Sakarya, Turkey. 5. Department of General Surgery, Faculty of Medicine, Katip Celebi University, Sakarya, Turkey.
Abstract
BACKGROUND: Idiopathic granulomatous mastitis (IGM) is a rare, benign, and chronic disease of the breast. Despite the various treatment approaches described for this disease, a gold standard treatment modality has not yet been defined. In this study, the effect of topical steroids was reviewed and assessed in patients with IGM. METHODS: The records of patients with IGM who were treated only with topical steroids were retrospectively reviewed. Patients were grouped as "completely healed," "inadequately healed," "stable," "worsened," or "recurred" if they had once healed but their symptoms returned. Patients whose skin changes were completely ameliorated were considered "completely healed." RESULTS: All of the patients were women, and the average patient age was 35.7 years (range 24-48 years). During the average follow-up of 37.2 months (range 12-72 months) in patients who received only topical steroid treatment, recurrence was observed in three patients (3/28, 10.7 %), and no side effects or steroid-related complications occurred. CONCLUSIONS: Topical steroids seem to be effective in the treatment of IGM characterized by skin changes. Prospective clinical studies would be useful in determining the clinical efficacy of topical steroids in the treatment of IGM.
BACKGROUND:Idiopathic granulomatous mastitis (IGM) is a rare, benign, and chronic disease of the breast. Despite the various treatment approaches described for this disease, a gold standard treatment modality has not yet been defined. In this study, the effect of topical steroids was reviewed and assessed in patients with IGM. METHODS: The records of patients with IGM who were treated only with topical steroids were retrospectively reviewed. Patients were grouped as "completely healed," "inadequately healed," "stable," "worsened," or "recurred" if they had once healed but their symptoms returned. Patients whose skin changes were completely ameliorated were considered "completely healed." RESULTS: All of the patients were women, and the average patient age was 35.7 years (range 24-48 years). During the average follow-up of 37.2 months (range 12-72 months) in patients who received only topical steroid treatment, recurrence was observed in three patients (3/28, 10.7 %), and no side effects or steroid-related complications occurred. CONCLUSIONS: Topical steroids seem to be effective in the treatment of IGM characterized by skin changes. Prospective clinical studies would be useful in determining the clinical efficacy of topical steroids in the treatment of IGM.
Authors: Eric C H Lai; Wing Cheong Chan; Tony K F Ma; Alice P Y Tang; Cycles S P Poon; Heng Tat Leong Journal: Breast J Date: 2005 Nov-Dec Impact factor: 2.431
Authors: Fazilet Erozgen; Yeliz E Ersoy; Murat Akaydin; Naim Memmi; Aysun Simsek Celik; Fatih Celebi; Deniz Guzey; Rafet Kaplan Journal: Breast Cancer Res Treat Date: 2010-07-13 Impact factor: 4.872
Authors: Dagmar Diesing; Roland Axt-Fliedner; Daniela Hornung; Jürgen M Weiss; Klaus Diedrich; Michael Friedrich Journal: Arch Gynecol Obstet Date: 2003-12-19 Impact factor: 2.344
Authors: Kenan Çetin; Hasan E Sıkar; Nuri E Göret; Günay Rona; Nagehan Ö Barışık; Hasan F Küçük; Bahadır M Gulluoglu Journal: World J Surg Date: 2019-11 Impact factor: 3.352
Authors: Omar Farouk; Mohamed Abdelkhalek; Ahmed Abdallah; Ahmed Shata; Ahmed Senbel; Essam Attia; Mohamed Abd Elghaffar; Mahmoud Mesbah; Nermine Soliman; Maha Amin; Dina El-Tantawy Journal: World J Surg Date: 2017-05 Impact factor: 3.352
Authors: Osman Toktas; Can Konca; Didem Can Trabulus; Aykut Soyder; Hande Koksal; Hasan Karanlik; Ayfer Kamali Polat; Serdar Ozbas; Serdar Yormaz; Arda Isik; Efe Sezgin; Atilla Soran Journal: Breast Care (Basel) Date: 2020-06-30 Impact factor: 2.860