Literature DB >> 24986019

Thromboembolic events in bariatric surgery: a large multi-institutional referral center experience.

Mohammad H Jamal1, Ricard Corcelles, Hideharu Shimizu, Mathew Kroh, Fernando M Safdie, Raul Rosenthal, Stacy A Brethauer, Philip R Schauer.   

Abstract

INTRODUCTION: The risk of venous thromboembolic (VTE) events is increased in patients undergoing bariatric surgery. Population studies examining VTE rates after bariatric surgery often lack details and uniformity regarding the prophylactic regimens used. The aim of this study was to determine the incidence of VTE in patients undergoing laparoscopic bariatric surgery.
METHODS: Database searches from Cleveland Clinic bariatric surgery programs in Cleveland, OH, and Weston, FL, were conducted from January 2005 to January 2013. Mechanical and chemical prophylaxes were provided for all patients as per protocol. Data on age, gender, body mass index (BMI), interval between procedure and VTE, inpatient versus outpatient status, anticoagulation prophylaxis, type of surgery and mortality were collected.
RESULTS: A total of 4,293 patients underwent primary or revisional bariatric surgery during this 8-year time period. VTE events were identified in 57 patients (1.3 %). Pulmonary embolism (PE) was identified in 39 patients (0.9 %), and 15 of these patients had negative duplex studies of the lower extremities. Deep venous thrombosis only was identified in 18 patients (0.4 %). VTE rates for gastric bypass (n = 2,945), sleeve gastrectomy (n = 709), gastric banding (n = 467) and revisional procedures (n = 171) were 1.1, 2.9, 0.2 and 6.4 %, respectively. Eight patients had VTE diagnosed during their inpatient stay. The mean time to VTE diagnosis after surgery was 24 days. Seventeen patients who developed VTE had been prescribed extended prophylaxis for 2-4 weeks after discharge. There was only one VTE-related mortality from PE reported in this cohort (0.02 %). Univariate and multivariate analyses revealed age, BMI, open and revisional surgery as predictive of VTE (p < 0.05).
CONCLUSION: The risk of VTE among morbidly obese patients undergoing bariatric surgery is persistent despite use of laparoscopy and aggressive prophylactic anticoagulation policy. Patients with advanced age, higher BMI and those undergoing open or revisional surgery are at higher risk of postoperative VTE.

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Year:  2014        PMID: 24986019     DOI: 10.1007/s00464-014-3678-4

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   4.584


  12 in total

1.  Pulmonary embolism complicating bariatric surgery: detailed analysis of a single institution's 24-year experience.

Authors:  Brennan J Carmody; Harvey J Sugerman; John M Kellum; Mohammed K Jamal; Jason M Johnson; Alfredo M Carbonell; James W Maher; Luke G Wolfe; Eric J DeMaria
Journal:  J Am Coll Surg       Date:  2006-10-25       Impact factor: 6.113

2.  Fatal complications of bariatric surgery.

Authors:  Lara B Goldfeder; Christine J Ren; James R Gill
Journal:  Obes Surg       Date:  2006-08       Impact factor: 4.129

3.  Preoperative placement of inferior vena cava filters and outcomes after gastric bypass surgery.

Authors:  Nancy J O Birkmeyer; David Share; Onur Baser; Arthur M Carlin; Jonathan F Finks; Carl M Pesta; Jeffrey A Genaw; John D Birkmeyer
Journal:  Ann Surg       Date:  2010-08       Impact factor: 12.969

4.  Clinical practice guidelines for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient--2013 update: cosponsored by American Association of Clinical Endocrinologists, The Obesity Society, and American Society for Metabolic & Bariatric Surgery.

Authors:  Jeffrey I Mechanick; Adrienne Youdim; Daniel B Jones; W Timothy Garvey; Daniel L Hurley; M Molly McMahon; Leslie J Heinberg; Robert Kushner; Ted D Adams; Scott Shikora; John B Dixon; Stacy Brethauer
Journal:  Obesity (Silver Spring)       Date:  2013-03       Impact factor: 5.002

5.  Pulmonary embolism and deep venous thrombosis following bariatric surgery.

Authors:  Paul D Stein; Fadi Matta
Journal:  Obes Surg       Date:  2013-05       Impact factor: 4.129

6.  Abdominal obesity is essential for the risk of venous thromboembolism in the metabolic syndrome: the Tromsø study.

Authors:  K H Borch; S K Braekkan; E B Mathiesen; I Njølstad; T Wilsgaard; J Størmer; J-B Hansen
Journal:  J Thromb Haemost       Date:  2008-11-24       Impact factor: 5.824

Review 7.  Pharmacologic and mechanical strategies for preventing venous thromboembolism after bariatric surgery: a systematic review and meta-analysis.

Authors:  Daniel J Brotman; Hasan M Shihab; Kalpana R Prakasa; Sosena Kebede; Elliott R Haut; Ritu Sharma; Kenneth Shermock; Yohalakshmi Chelladurai; Sonal Singh; Jodi B Segal
Journal:  JAMA Surg       Date:  2013-07       Impact factor: 14.766

8.  Mortality after bariatric surgery: analysis of 13,871 morbidly obese patients from a national registry.

Authors:  Mario Morino; Mauro Toppino; Pietro Forestieri; Luigi Angrisani; Marco Ettore Allaix; Nicola Scopinaro
Journal:  Ann Surg       Date:  2007-12       Impact factor: 12.969

9.  Predicting risk for venous thromboembolism with bariatric surgery: results from the Michigan Bariatric Surgery Collaborative.

Authors:  Jonathan F Finks; Wayne J English; Arthur M Carlin; Kevin R Krause; David A Share; Mousumi Banerjee; John D Birkmeyer; Nancy J Birkmeyer
Journal:  Ann Surg       Date:  2012-06       Impact factor: 12.969

10.  Cardiovascular risk factors and venous thromboembolism: a meta-analysis.

Authors:  Walter Ageno; Cecilia Becattini; Timothy Brighton; Rita Selby; Pieter W Kamphuisen
Journal:  Circulation       Date:  2007-12-17       Impact factor: 29.690

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  15 in total

Review 1.  [Management of complications after bariatric surgery].

Authors:  B Wölnerhanssen; R Peterli
Journal:  Chirurg       Date:  2015-12       Impact factor: 0.955

2.  Incidence of Venous Thromboembolism Following Laparoscopic Surgery for Gastrointestinal Cancer: A Single-Center, Prospective Cohort Study.

Authors:  Yasue Kimura; Eiji Oki; Koji Ando; Hiroshi Saeki; Tetsuya Kusumoto; Yoshihiko Maehara
Journal:  World J Surg       Date:  2016-02       Impact factor: 3.352

3.  Haemostatic and fibrinolytic changes in obese subjects undergoing bariatric surgery: the effect of different surgical procedures.

Authors:  Roberta Lupoli; Marco Milone; Alessandro Di Minno; Paola Maietta; Pasquale Ambrosino; Mario Musella; Matteo N D Di Minno
Journal:  Blood Transfus       Date:  2014-12-16       Impact factor: 3.443

4.  What's new in postoperative intensive care after bariatric surgery?

Authors:  Philippe Montravers; Lara Ribeiro-Parenti; Camille Welsch
Journal:  Intensive Care Med       Date:  2015-02-12       Impact factor: 17.440

5.  Analysis of National Bariatric Surgery Related Clinical Incidents: Lessons Learned and a Proposed Safety Checklist for Bariatric Surgery.

Authors:  Islam Omar; Brijesh Madhok; Chetan Parmar; Omar Khan; Michael Wilson; Kamal Mahawar
Journal:  Obes Surg       Date:  2021-03-05       Impact factor: 4.129

6.  Pharmacokinetics and pharmacodynamics of single doses of rivaroxaban in obese patients prior to and after bariatric surgery.

Authors:  Dino Kröll; Guido Stirnimann; Andreas Vogt; Desirée Lin Lee Lai; Yves Michael Borbély; Julia Altmeier; Sabine Schädelin; Daniel Candinas; Lorenzo Alberio; Philipp C Nett
Journal:  Br J Clin Pharmacol       Date:  2017-03-09       Impact factor: 4.335

Review 7.  Efficacy and safety of pre-operative insertion of inferior vena cava filter in patients undergoing bariatric surgery: a systematic review.

Authors:  Rick Ikesaka; Bhagwanpreet Kaur; Mark Crowther; Anita Rajasekhar
Journal:  J Thromb Thrombolysis       Date:  2022-08-12       Impact factor: 5.221

8.  Low molecular weight heparin once versus twice for thromboprophylaxis following esophagectomy: a randomised, double-blind and placebo-controlled trial.

Authors:  Jie-Qiong Song; Li-Zhen Xuan; Wei Wu; Jun-Feng Huang; Ming Zhong
Journal:  J Thorac Dis       Date:  2015-07       Impact factor: 2.895

9.  Evaluation of VTE prophylaxis and the impact of alternate regimens on post-operative bleeding and thrombotic complications following bariatric procedures.

Authors:  Maria S Altieri; Jie Yang; Janos Hajagos; Konstantinos Spaniolas; Jihye Park; Antonios P Gasparis; Andrew T Bates; Salvatore Docimo; Mark Talamini; A Laurie Shroyer; Aurora D Pryor
Journal:  Surg Endosc       Date:  2018-05-15       Impact factor: 4.584

10.  Use of post-discharge heparin prophylaxis and the risk of venous thromboembolism and bleeding following bariatric surgery.

Authors:  Erin B Fennern; Farhood Farjah; Judy Y Chen; Francys C Verdial; Sara B Cook; Erika M Wolff; Saurabh Khandelwal
Journal:  Surg Endosc       Date:  2020-10-06       Impact factor: 4.584

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