Literature DB >> 24978287

2013 Dade W. Moeller lecture: medical countermeasures against radiological terrorism.

John E Moulder1.   

Abstract

Soon after the 9-11 attacks, politicians and scientists began to question our ability to cope with a large-scale radiological terrorism incident. The outline of what was needed was fairly obvious: the ability to prevent such an attack, methods to cope with the medical consequences, the ability to clean up afterward, and the tools to figure out who perpetrated the attack and bring them to justice. The medical response needed three components: the technology to determine rapidly the radiation doses received by a large number of people, methods for alleviating acute hematological radiation injuries, and therapies for mitigation and treatment of chronic radiation injuries. Research done to date has shown that a realistic medical response plan is scientifically possible, but the regulatory and financial barriers to achieving this may currently be insurmountable.

Entities:  

Mesh:

Year:  2014        PMID: 24978287      PMCID: PMC4076685          DOI: 10.1097/HP.0000000000000082

Source DB:  PubMed          Journal:  Health Phys        ISSN: 0017-9078            Impact factor:   1.316


  59 in total

1.  Detection of partial-body exposure to ionizing radiation by the automatic detection of dicentrics.

Authors:  Aurelie Vaurijoux; Eric Gregoire; Sandrine Roch-Lefevre; Pascale Voisin; Cecile Martin; Philippe Voisin; Laurence Roy; Gaetan Gruel
Journal:  Radiat Res       Date:  2011-12-15       Impact factor: 2.841

Review 2.  Radiation as a risk factor for cardiovascular disease.

Authors:  John E Baker; John E Moulder; John W Hopewell
Journal:  Antioxid Redox Signal       Date:  2011-03-23       Impact factor: 8.401

Review 3.  Priority list of research areas for radiological nuclear threat countermeasures.

Authors:  Terry C Pellmar; Sara Rockwell
Journal:  Radiat Res       Date:  2005-01       Impact factor: 2.841

4.  Intestinal microbiota as novel biomarkers of prior radiation exposure.

Authors:  Vy Lam; John E Moulder; Nita H Salzman; Eric A Dubinsky; Gary L Andersen; John E Baker
Journal:  Radiat Res       Date:  2012-03-23       Impact factor: 2.841

5.  Medical management of radiological casualties.

Authors:  Ronald E Goans; Jamie K Waselenko
Journal:  Health Phys       Date:  2005-11       Impact factor: 1.316

6.  An improved model for predicting radiation pneumonitis incorporating clinical and dosimetric variables.

Authors:  Peter Jenkins; Joanne Watts
Journal:  Int J Radiat Oncol Biol Phys       Date:  2011-05-03       Impact factor: 7.038

7.  Dosimetry based on EPR spectral analysis of fingernail clippings.

Authors:  Dean E Wilcox; Xiaoming He; Jiang Gui; Andres E Ruuge; Hongbin Li; Benjamin B Williams; Harold M Swartz
Journal:  Health Phys       Date:  2010-02       Impact factor: 1.316

8.  Development of in vivo tooth EPR for individual radiation dose estimation and screening.

Authors:  Benjamin B Williams; Ruhong Dong; Maciej Kmiec; Greg Burke; Eugene Demidenko; David Gladstone; Roberto J Nicolalde; Artur Sucheta; Piotr Lesniewski; Harold M Swartz
Journal:  Health Phys       Date:  2010-02       Impact factor: 1.316

9.  Radiation metabolomics. 5. Identification of urinary biomarkers of ionizing radiation exposure in nonhuman primates by mass spectrometry-based metabolomics.

Authors:  Caroline H Johnson; Andrew D Patterson; Kristopher W Krausz; John F Kalinich; John B Tyburski; Dong Wook Kang; Hans Luecke; Frank J Gonzalez; William F Blakely; Jeffrey R Idle
Journal:  Radiat Res       Date:  2012-09-06       Impact factor: 2.841

10.  A novel method for biodosimetry.

Authors:  Wael Abdel Megid; Martin G Ensenberger; Richard B Halberg; Stephen A Stanhope; Marijo G Kent-First; Tomas A Prolla; Jeff W Bacher
Journal:  Radiat Environ Biophys       Date:  2006-10-27       Impact factor: 2.017

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  15 in total

1.  Effects of Diet on Late Radiation Injuries in Rats.

Authors:  John E Moulder; Brian L Fish; Eric P Cohen; Jessica B Flowers; Meetha Medhora
Journal:  Health Phys       Date:  2019-04       Impact factor: 1.316

2.  Delayed Effects of Acute Radiation Exposure (Deare) in Juvenile and Old Rats: Mitigation by Lisinopril.

Authors:  Meetha Medhora; Feng Gao; Tracy Gasperetti; Jayashree Narayanan; Abdul Hye Khan; Elizabeth R Jacobs; Brian L Fish
Journal:  Health Phys       Date:  2019-04       Impact factor: 1.316

Review 3.  Metabolomic applications in radiation biodosimetry: exploring radiation effects through small molecules.

Authors:  Evan L Pannkuk; Albert J Fornace; Evagelia C Laiakis
Journal:  Int J Radiat Biol       Date:  2017-01-12       Impact factor: 2.694

4.  Rat Models of Partial-body Irradiation with Bone Marrow-sparing (Leg-out PBI) Designed for FDA Approval of Countermeasures for Mitigation of Acute and Delayed Injuries by Radiation.

Authors:  Brian L Fish; Thomas J MacVittie; Feng Gao; Jayashree Narayanan; Tracy Gasperetti; Dana Scholler; Yuri Sheinin; Heather A Himburg; Barry Hart; Meetha Medhora
Journal:  Health Phys       Date:  2021-10-01       Impact factor: 2.922

5.  Vascular regression in the kidney: changes in 3D vessel structure with time post-irradiation.

Authors:  Soudeh Mostaghimi; Shima Mehrvar; Farnaz H Foomani; Jayashree Narayanan; Brian Fish; Amadou K S Camara; Meetha Medhora; Mahsa Ranji
Journal:  Biomed Opt Express       Date:  2022-07-26       Impact factor: 3.562

6.  Mitigation of experimental radiation nephropathy by renin-equivalent doses of angiotensin converting enzyme inhibitors.

Authors:  John E Moulder; Eric P Cohen; Brian L Fish
Journal:  Int J Radiat Biol       Date:  2014-09       Impact factor: 2.694

7.  Clinically Relevant Doses of Enalapril Mitigate Multiple Organ Radiation Injury.

Authors:  Eric P Cohen; Brian L Fish; John E Moulder
Journal:  Radiat Res       Date:  2016-03-02       Impact factor: 2.841

Review 8.  Addressing the Symptoms or Fixing the Problem? Developing Countermeasures against Normal Tissue Radiation Injury.

Authors:  Jacqueline P Williams; Laura Calvi; Joe V Chakkalakal; Jacob N Finkelstein; M Kerry O'Banion; Edward Puzas
Journal:  Radiat Res       Date:  2016-06-22       Impact factor: 2.841

9.  Simvastatin mitigates increases in risk factors for and the occurrence of cardiac disease following 10 Gy total body irradiation.

Authors:  Marek Lenarczyk; Jidong Su; Steven T Haworth; Richard Komorowski; Brian L Fish; Raymond Q Migrino; Leanne Harmann; John W Hopewell; Amy Kronenberg; Shailendra Patel; John E Moulder; John E Baker
Journal:  Pharmacol Res Perspect       Date:  2015-06-01

10.  Polypharmacy to Mitigate Acute and Delayed Radiation Syndromes.

Authors:  Tracy Gasperetti; Tessa Miller; Feng Gao; Jayashree Narayanan; Elizabeth R Jacobs; Aniko Szabo; George N Cox; Christie M Orschell; Brian L Fish; Meetha Medhora
Journal:  Front Pharmacol       Date:  2021-05-17       Impact factor: 5.810

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