Literature DB >> 24950086

Vector integration and tumorigenesis.

Christof von Kalle1, Annette Deichmann, Manfred Schmidt.   

Abstract

Mesh:

Year:  2014        PMID: 24950086      PMCID: PMC4064723          DOI: 10.1089/hum.2014.2525

Source DB:  PubMed          Journal:  Hum Gene Ther        ISSN: 1043-0342            Impact factor:   5.695


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  70 in total

Review 1.  Targeting survival: integration site selection by retroviruses and LTR-retrotransposons.

Authors:  Frederic D Bushman
Journal:  Cell       Date:  2003-10-17       Impact factor: 41.582

2.  A largely random AAV integration profile after LPLD gene therapy.

Authors:  Christine Kaeppel; Stuart G Beattie; Raffaele Fronza; Richard van Logtenstein; Florence Salmon; Sabine Schmidt; Stephan Wolf; Ali Nowrouzi; Hanno Glimm; Christof von Kalle; Harald Petry; Daniel Gaudet; Manfred Schmidt
Journal:  Nat Med       Date:  2013-06-16       Impact factor: 53.440

3.  Bioinformatic clonality analysis of next-generation sequencing-derived viral vector integration sites.

Authors:  Anne Arens; Jens-Uwe Appelt; Cynthia C Bartholomae; Richard Gabriel; Anna Paruzynski; Derek Gustafson; Nathalie Cartier; Patrick Aubourg; Annette Deichmann; Hanno Glimm; Christof von Kalle; Manfred Schmidt
Journal:  Hum Gene Ther Methods       Date:  2012-05-04       Impact factor: 2.396

4.  LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1.

Authors:  S Hacein-Bey-Abina; C Von Kalle; M Schmidt; M P McCormack; N Wulffraat; P Leboulch; A Lim; C S Osborne; R Pawliuk; E Morillon; R Sorensen; A Forster; P Fraser; J I Cohen; G de Saint Basile; I Alexander; U Wintergerst; T Frebourg; A Aurias; D Stoppa-Lyonnet; S Romana; I Radford-Weiss; F Gross; F Valensi; E Delabesse; E Macintyre; F Sigaux; J Soulier; L E Leiva; M Wissler; C Prinz; T H Rabbitts; F Le Deist; A Fischer; M Cavazzana-Calvo
Journal:  Science       Date:  2003-10-17       Impact factor: 47.728

5.  AAV serotype 2 vectors preferentially integrate into active genes in mice.

Authors:  Hiroyuki Nakai; Eugenio Montini; Sally Fuess; Theresa A Storm; Markus Grompe; Mark A Kay
Journal:  Nat Genet       Date:  2003-07       Impact factor: 38.330

6.  Gene therapy for Wiskott-Aldrich syndrome--long-term efficacy and genotoxicity.

Authors:  Christian Jörg Braun; Kaan Boztug; Anna Paruzynski; Maximilian Witzel; Adrian Schwarzer; Michael Rothe; Ute Modlich; Rita Beier; Gudrun Göhring; Doris Steinemann; Raffaele Fronza; Claudia Regina Ball; Reinhard Haemmerle; Sonja Naundorf; Klaus Kühlcke; Martina Rose; Chris Fraser; Liesl Mathias; Rudolf Ferrari; Miguel R Abboud; Waleed Al-Herz; Irina Kondratenko; László Maródi; Hanno Glimm; Brigitte Schlegelberger; Axel Schambach; Michael Heinrich Albert; Manfred Schmidt; Christof von Kalle; Christoph Klein
Journal:  Sci Transl Med       Date:  2014-03-12       Impact factor: 17.956

7.  Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome.

Authors:  Alessandro Aiuti; Luca Biasco; Samantha Scaramuzza; Francesca Ferrua; Maria Pia Cicalese; Cristina Baricordi; Francesca Dionisio; Andrea Calabria; Stefania Giannelli; Maria Carmina Castiello; Marita Bosticardo; Costanza Evangelio; Andrea Assanelli; Miriam Casiraghi; Sara Di Nunzio; Luciano Callegaro; Claudia Benati; Paolo Rizzardi; Danilo Pellin; Clelia Di Serio; Manfred Schmidt; Christof Von Kalle; Jason Gardner; Nalini Mehta; Victor Neduva; David J Dow; Anne Galy; Roberto Miniero; Andrea Finocchi; Ayse Metin; Pinaki P Banerjee; Jordan S Orange; Stefania Galimberti; Maria Grazia Valsecchi; Alessandra Biffi; Eugenio Montini; Anna Villa; Fabio Ciceri; Maria Grazia Roncarolo; Luigi Naldini
Journal:  Science       Date:  2013-07-11       Impact factor: 47.728

8.  The BET family of proteins targets moloney murine leukemia virus integration near transcription start sites.

Authors:  Jan De Rijck; Christine de Kogel; Jonas Demeulemeester; Sofie Vets; Sara El Ashkar; Nirav Malani; Frederic D Bushman; Bart Landuyt; Steven J Husson; Katrien Busschots; Rik Gijsbers; Zeger Debyser
Journal:  Cell Rep       Date:  2013-10-31       Impact factor: 9.423

9.  Transcription start regions in the human genome are favored targets for MLV integration.

Authors:  Xiaolin Wu; Yuan Li; Bruce Crise; Shawn M Burgess
Journal:  Science       Date:  2003-06-13       Impact factor: 47.728

10.  Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy.

Authors:  Alessandra Biffi; Eugenio Montini; Laura Lorioli; Martina Cesani; Francesca Fumagalli; Tiziana Plati; Cristina Baldoli; Sabata Martino; Andrea Calabria; Sabrina Canale; Fabrizio Benedicenti; Giuliana Vallanti; Luca Biasco; Simone Leo; Nabil Kabbara; Gianluigi Zanetti; William B Rizzo; Nalini A L Mehta; Maria Pia Cicalese; Miriam Casiraghi; Jaap J Boelens; Ubaldo Del Carro; David J Dow; Manfred Schmidt; Andrea Assanelli; Victor Neduva; Clelia Di Serio; Elia Stupka; Jason Gardner; Christof von Kalle; Claudio Bordignon; Fabio Ciceri; Attilio Rovelli; Maria Grazia Roncarolo; Alessandro Aiuti; Maria Sessa; Luigi Naldini
Journal:  Science       Date:  2013-07-11       Impact factor: 47.728

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  5 in total

1.  Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection.

Authors:  Justin Eyquem; Jorge Mansilla-Soto; Theodoros Giavridis; Sjoukje J C van der Stegen; Mohamad Hamieh; Kristen M Cunanan; Ashlesha Odak; Mithat Gönen; Michel Sadelain
Journal:  Nature       Date:  2017-02-22       Impact factor: 49.962

2.  Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors.

Authors:  Beau R Webber; Cara-Lin Lonetree; Mitchell G Kluesner; Matthew J Johnson; Emily J Pomeroy; Miechaleen D Diers; Walker S Lahr; Garrett M Draper; Nicholas J Slipek; Branden A Smeester; Klaus N Lovendahl; Amber N McElroy; Wendy R Gordon; Mark J Osborn; Branden S Moriarity
Journal:  Nat Commun       Date:  2019-11-19       Impact factor: 14.919

Review 3.  Nanotechnology Promotes Genetic and Functional Modifications of Therapeutic T Cells Against Cancer.

Authors:  Ahmed M E Abdalla; Lin Xiao; Yu Miao; Lixia Huang; Gendeal M Fadlallah; Mario Gauthier; Chenxi Ouyang; Guang Yang
Journal:  Adv Sci (Weinh)       Date:  2020-02-20       Impact factor: 16.806

Review 4.  T-Cell Dysfunction as a Limitation of Adoptive Immunotherapy: Current Concepts and Mitigation Strategies.

Authors:  Valérie Janelle; Jean-Sébastien Delisle
Journal:  Cancers (Basel)       Date:  2021-02-03       Impact factor: 6.639

Review 5.  A review of the underlying genetics and emerging therapies for canine cardiomyopathies.

Authors:  L Shen; A H Estrada; K M Meurs; M Sleeper; C Vulpe; C J Martyniuk; C A Pacak
Journal:  J Vet Cardiol       Date:  2021-05-21       Impact factor: 1.750

  5 in total

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