Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Targeting survival: integration site selection by retroviruses and LTR-retrotransposons.

Literature DB >> 14567911

Targeting survival: integration site selection by retroviruses and LTR-retrotransposons.

Abstract

Replication of retroviruses and retrotransposons depends on selecting a favorable chromosomal site for integration of their genomic DNA. Different retroelements meet this challenge by targeting distinctive chromosomal regions. Despite these differences, recent data hints at a common targeting mechanism-tethering of integration complexes to proteins bound at favorable sites.

Mesh：

Substances：

Year: 2003 PMID： 14567911 DOI： 10.1016/s0092-8674(03)00760-8

Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582

Keyword Cloud
Cited

94 in total

1. An active murine transposon family pair: retrotransposition of "master" MusD copies and ETn trans-mobilization.

Authors: David Ribet; Marie Dewannieux; Thierry Heidmann
Journal: Genome Res Date: 2004-10-12 Impact factor: 9.043

Review 2. A realistic chance for gene therapy in the near future.

Authors: Stefan Worgall
Journal: Pediatr Nephrol Date: 2004-11-10 Impact factor: 3.714

3. Comprehensive analysis of microRNA genomic loci identifies pervasive repetitive-element origins.

Authors: Glen M Borchert; Nathaniel W Holton; Jonathan D Williams; William L Hernan; Ian P Bishop; Joel A Dembosky; James E Elste; Nathaniel S Gregoire; Jee-Ah Kim; Wesley W Koehler; Joe C Lengerich; Arianna A Medema; Marilyn A Nguyen; Geoffrey D Ower; Michelle A Rarick; Brooke N Strong; Nicholas J Tardi; Nathan M Tasker; Darren J Wozniak; Craig Gatto; Erik D Larson
Journal: Mob Genet Elements Date: 2011-05

4. Sleeping Beauty transposon mutagenesis in rat spermatogonial stem cells.

Authors: Zoltán Ivics; Zsuzsanna Izsvák; Gerardo Medrano; Karen M Chapman; F Kent Hamra
Journal: Nat Protoc Date: 2011-09-08 Impact factor: 13.491

5. A high-throughput method for cloning and sequencing human immunodeficiency virus type 1 integration sites.

Authors: Sanggu Kim; Yein Kim; Teresa Liang; Janet S Sinsheimer; Samson A Chow
Journal: J Virol Date: 2006-09-13 Impact factor: 5.103

6. Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo.

Authors: Kerstin Schwarzwaelder; Steven J Howe; Manfred Schmidt; Martijn H Brugman; Annette Deichmann; Hanno Glimm; Sonja Schmidt; Claudia Prinz; Manuela Wissler; Douglas J S King; Fang Zhang; Kathryn L Parsley; Kimberly C Gilmour; Joanna Sinclair; Jinhua Bayford; Rachel Peraj; Karin Pike-Overzet; Frank J T Staal; Dick de Ridder; Christine Kinnon; Ulrich Abel; Gerard Wagemaker; H Bobby Gaspar; Adrian J Thrasher; Christof von Kalle
Journal: J Clin Invest Date: 2007-08 Impact factor: 14.808

7. Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy.

Authors: Annette Deichmann; Salima Hacein-Bey-Abina; Manfred Schmidt; Alexandrine Garrigue; Martijn H Brugman; Jingqiong Hu; Hanno Glimm; Gabor Gyapay; Bernard Prum; Christopher C Fraser; Nicolas Fischer; Kerstin Schwarzwaelder; Maria-Luise Siegler; Dick de Ridder; Karin Pike-Overzet; Steven J Howe; Adrian J Thrasher; Gerard Wagemaker; Ulrich Abel; Frank J T Staal; Eric Delabesse; Jean-Luc Villeval; Bruce Aronow; Christophe Hue; Claudia Prinz; Manuela Wissler; Chuck Klanke; Jean Weissenbach; Ian Alexander; Alain Fischer; Christof von Kalle; Marina Cavazzana-Calvo
Journal: J Clin Invest Date: 2007-08 Impact factor: 14.808