Literature DB >> 24936307

Measurement of flow diverter hydraulic resistance to model flow modification in and around intracranial aneurysms.

Adám Ugron, István Szikora, György Paál.   

Abstract

Flow diverters (FDs) have been successfully applied in the recent decade to the treatment of intracranial aneurysms by impairing the communication between the flows in the parent artery and the aneurysm and, thus, the blood within the aneurysm sac. It would be desirable to have a simple and accurate computational method to follow the changes in the peri- and intraaneurysmal flow caused by the presence of FDs. The detailed flow simulation around the intricate wire structure of the FDs has three disadvantages: need for high amount of computational resources and highly skilled professionals to prepare the computational grid, and also the lack of validation that makes the invested effort questionable. In this paper, we propose a porous layer method to model the hydraulic resistance (HR) of one or several layers of the FDs. The basis of this proposal is twofold: first, from an application point of view, the only interesting parameter regarding the function of the FD is its HR; second, we have developed a method to measure the HR with a simple apparatus. We present the results of these measurements and demonstrate their utility in numerical simulations of patient-specific aneurysm simulations.

Entities:  

Keywords:  computational fluid dynamics; flow diversion; intracranial aneurysm; pressure; wall shear stress

Year:  2014        PMID: 24936307      PMCID: PMC4047506          DOI: 10.1556/IMAS.6.2014.2.2

Source DB:  PubMed          Journal:  Interv Med Appl Sci        ISSN: 2061-1617


  15 in total

Review 1.  Computational fluid dynamics in brain aneurysms.

Authors:  Daniel M Sforza; Christopher M Putman; Juan R Cebral
Journal:  Int J Numer Method Biomed Eng       Date:  2011-11-28       Impact factor: 2.747

2.  Aneurysm rupture following treatment with flow-diverting stents: computational hemodynamics analysis of treatment.

Authors:  J R Cebral; F Mut; M Raschi; E Scrivano; R Ceratto; P Lylyk; C M Putman
Journal:  AJNR Am J Neuroradiol       Date:  2010-11-11       Impact factor: 3.825

3.  Intra-aneurysmal thrombosis as a possible cause of delayed aneurysm rupture after flow-diversion treatment.

Authors:  Z Kulcsár; E Houdart; A Bonafé; G Parker; J Millar; A J P Goddard; S Renowden; G Gál; B Turowski; K Mitchell; F Gray; M Rodriguez; R van den Berg; A Gruber; H Desal; I Wanke; D A Rüfenacht
Journal:  AJNR Am J Neuroradiol       Date:  2010-11-11       Impact factor: 3.825

4.  Hemodynamics of cerebral aneurysm initiation: the role of wall shear stress and spatial wall shear stress gradient.

Authors:  Z Kulcsár; A Ugron; M Marosfoi; Z Berentei; G Paál; I Szikora
Journal:  AJNR Am J Neuroradiol       Date:  2011-02-10       Impact factor: 3.825

5.  The pipeline embolization device for the intracranial treatment of aneurysms trial.

Authors:  P K Nelson; P Lylyk; I Szikora; S G Wetzel; I Wanke; D Fiorella
Journal:  AJNR Am J Neuroradiol       Date:  2010-12-09       Impact factor: 3.825

6.  Treatment of intracranial aneurysms by functional reconstruction of the parent artery: the Budapest experience with the pipeline embolization device.

Authors:  I Szikora; Z Berentei; Z Kulcsar; M Marosfoi; Z S Vajda; W Lee; A Berez; P K Nelson
Journal:  AJNR Am J Neuroradiol       Date:  2010-02-11       Impact factor: 3.825

7.  Effects of size and shape (aspect ratio) on the hemodynamics of saccular aneurysms: a possible index for surgical treatment of intracranial aneurysms.

Authors:  H Ujiie; H Tachibana; O Hiramatsu; A L Hazel; T Matsumoto; Y Ogasawara; H Nakajima; T Hori; K Takakura; F Kajiya
Journal:  Neurosurgery       Date:  1999-07       Impact factor: 4.654

Review 8.  Reproducibility of haemodynamical simulations in a subject-specific stented aneurysm model--a report on the Virtual Intracranial Stenting Challenge 2007.

Authors:  A G Radaelli; L Augsburger; J R Cebral; M Ohta; D A Rüfenacht; R Balossino; G Benndorf; D R Hose; A Marzo; R Metcalfe; P Mortier; F Mut; P Reymond; L Socci; B Verhegghe; A F Frangi
Journal:  J Biomech       Date:  2008-06-25       Impact factor: 2.712

9.  Curative endovascular reconstruction of cerebral aneurysms with the pipeline embolization device: the Buenos Aires experience.

Authors:  Pedro Lylyk; Carlos Miranda; Rosana Ceratto; Angel Ferrario; Esteban Scrivano; Hugh Ramirez Luna; Aaron L Berez; Quang Tran; Peter K Nelson; David Fiorella
Journal:  Neurosurgery       Date:  2009-04       Impact factor: 4.654

10.  Impact of aneurysmal geometry on intraaneurysmal flow: a computerized flow simulation study.

Authors:  Istvan Szikora; Gyorgy Paal; Adam Ugron; Ferenc Nasztanovics; Miklos Marosfoi; Zsolt Berentei; Zsolt Kulcsar; Wickly Lee; Imre Bojtar; Istvan Nyary
Journal:  Neuroradiology       Date:  2008-05       Impact factor: 2.804

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  3 in total

1.  Changes in contrast transit times on digital subtraction angiography post-Pipeline Embolization Device deployment.

Authors:  Ahmed E Hussein; Andreas Linninger; Sophia F Shakur; Fady T Charbel; Chih-Yang Hsu; Fady T Charbel; Ali Alaraj
Journal:  Interv Neuroradiol       Date:  2017-01-17       Impact factor: 1.610

2.  Impact of Design and Deployment Technique on the Hydrodynamic Resistance of Flow Diverters : An in Vitro Experimental Study.

Authors:  Dániel Gyürki; Benjamin Csippa; György Paál; István Szikora
Journal:  Clin Neuroradiol       Date:  2021-10-22       Impact factor: 3.649

3.  Hydrodynamic Resistance of Intracranial Flow-Diverter Stents: Measurement Description and Data Evaluation.

Authors:  Benjamin Csippa; Dániel Gyürki; Gábor Závodszky; István Szikora; György Paál
Journal:  Cardiovasc Eng Technol       Date:  2019-12-03       Impact factor: 2.495

  3 in total

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