| Literature DB >> 24935893 |
Sherry L Emery1, Lisa Vera2, Jidong Huang1, Glen Szczypka1.
Abstract
BACKGROUND: Awareness and use of electronic cigarettes has rapidly grown in the USA recently, in step with increased product marketing. Using responses to a population survey of US adults, we analysed demographic patterns of exposure to, searching for and sharing of e-cigarette-related information across media platforms.Entities:
Keywords: Advertising and Promotion; Electronic nicotine delivery devices; Media
Mesh:
Substances:
Year: 2014 PMID: 24935893 PMCID: PMC4078680 DOI: 10.1136/tobaccocontrol-2014-051648
Source DB: PubMed Journal: Tob Control ISSN: 0964-4563 Impact factor: 7.552
Descriptive statistics
| Number of observations | Per cent/mean | 95% CI) (%) | |
|---|---|---|---|
| Dependent variables | |||
| Seen/heard information about e-cigarettes | 17 452 | 47.70 | 46.5 to 48.9 |
| Searched for information about e-cigarettes | 17 452 | 4.90 | 4.5 to 5.4 |
| Shared information about e-cigarettes | 17 452 | 2.00 | 1.7 to 2.3 |
| Shared information conditional on seen/heard | 8835 | 2.00 | 1.6 to 2.4 |
| Shared information conditional on searched | 1449 | 16.00 | 12.8 to 19.1 |
| E-cigarette prevalence | |||
| E-cigarettes awareness | 17 480 | 86.40 | 85.6 to 87.3 |
| Ever used e-cigarettes | 17 477 | 14.80 | 14.0 to 15.5 |
| Current use e-cigarettes | 17 477 | 5.10 | 4.7 to 5.5 |
| Explanatory variables | |||
| Tobacco user indicator | 17 522 | 25.10 | 24.2 to 25.9 |
| Age category | |||
| 18–24: 1, yes; 0, no (reference) | 17 522 | 9.70 | 8.9 to 10.5 |
| 25–44: 1, yes; 0, no | 17 522 | 34.40 | 33.3 to 35.6 |
| 45–64: 1, yes; 0, no | 17 522 | 38.30 | 37.2 to 39.4 |
| 65+: 1, yes; 0, no | 17 522 | 17.50 | 16.7 to 18.4 |
| Gender: 0, male; 1, female | 17 522 | 52.00 | 50.8 to 53.2 |
| Race/ethnicity | |||
| Non-Hispanic white: 1, yes; 0, no (reference) | 17 522 | 68.10 | 66.9 to 69.3 |
| Non-Hispanic black: 1, yes; 0, no | 17 522 | 11.50 | 10.7 to 12.4 |
| Hispanic: 1, yes; 0, no | 17 522 | 13.50 | 12.5 to 14.4 |
| Other: 1, yes; 0, no | 17 522 | 6.90 | 6.2 to 7.5 |
| Education | |||
| Less than high school graduate: 1, yes; 0, no (reference) | 17 522 | 6.80 | 6.1 to 7.5 |
| High school graduate: 1, yes; 0, no | 17 522 | 36.10 | 35.0 to 37.3 |
| Some college: 1, yes; 0, no | 17 522 | 31.20 | 30.1 to 32.2 |
| College: 1, yes; 0, no | 17 522 | 15.70 | 15.0 to 16.5 |
| Any postcollege: 1, yes; 0, no | 17 522 | 10.20 | 9.6 to 10.9 |
| Household income | |||
| <20K: 1, yes; 0, no (reference) | 17 522 | 14.20 | 13.3 to 15.0 |
| 20–34.9K: 1, yes; 0, no | 17 522 | 14.90 | 14.1 to 15.8 |
| 35–49.9K: 1, yes; 0, no | 17 522 | 13.30 | 12.5 to 14.0 |
| 50–74.9K: 1, yes; 0, no | 17 522 | 19.60 | 18.7 to 20.6 |
| 75–124.9K: 1, yes; 0, no | 17 522 | 27.40 | 26.4 to 28.5 |
| 125K+: 1, yes; 0, no | 17 522 | 10.60 | 9.9 to 11.3 |
| LGB category: 0, heterosexual or straight; 1, lesbian, gay, bisexual | 17 281 | 4.90 | 4.4 to 5.4 |
| Use social networking sites: 1, yes; 0, no | 17 474 | 87.40 | 86.7 to 88.2 |
| Average daily hours spent on internet | 17 024 | 3.05 | 3.00 to 3.10 |
LGB, lesbian, gay and bisexual.
Logistic regression with state fixed effects
| E-cigarette-related information? | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Seen/heard | Searched for | Shared | Shared conditional on seen/heard | Shared conditional on searched | ||||||
| OR (95% CI) | p Value | OR (95% CI) | p Value | OR (95% CI) | p Value | OR (95% CI) | p Value | OR (95% CI) | p Value | |
| Tobacco user | ||||||||||
| No | 1 | 1 | 1 | 1 | 1 | |||||
| Yes | 1.90 (1.70 to 2.11) | <0.0001 | 8.37 (6.39 to 10.96) | <0.0001 | 5.23 (3.57 to 7.68) | <.0001 | 5.24 (2.90 to 9.48) | <0.0001 | 0.94 (0.50 to 1.75) | 0.8376 |
| Age | ||||||||||
| 18–24 | 1 | 1 | 1 | 1 | 1 | |||||
| 25–44 | 0.97 (0.79 to 1.20) | 0.7940 | 0.71 (0.50 to 1.01) | 0.0585 | 0.51 (0.33 to 0.81) | 0.0039 | 0.37 (0.21 to 0.68) | 0.0011 | 0.97 (0.45 to 2.11) | 0.9385 |
| 45–64 | 0.89 (0.72 to 1.09) | 0.2534 | 0.64 (0.45 to 0.92) | 0.0152 | 0.46 (0.29 to 0.71) | 0.0006 | 0.48 (0.26 to 0.89) | 0.0194 | 1.01 (0.45 to 2.24) | 0.9827 |
| 65+ | 0.80 (0.64 to 1.00) | 0.0506 | 0.40 (0.25 to 0.64) | 0.0001 | 0.36 (0.19 to 0.69) | 0.0022 | 0.18 (0.08 to 0.41) | <0.0001 | 0.17 (0.05 to 0.54) | 0.0027 |
| Gender | ||||||||||
| Male | 1 | 1 | 1 | 1 | 1 | |||||
| Female | 0.80 (0.72 to 0.88) | <0.0001 | 1.27 (1.05 to 1.55) | 0.0160 | 1.22 (0.91 to 1.63) | 0.1874 | 1.33 (0.88 to 2.00) | 0.1779 | 0.97 (0.62 to 1.53) | 0.9010 |
| Race | ||||||||||
| White | 1 | 1 | 1 | 1 | 1 | |||||
| Black | 0.98 (0.83 to 1.17) | 0.8584 | 0.80 (0.55 to 1.17) | 0.2480 | 1.09 (0.67 to 1.79) | 0.7317 | 0.50 (0.25 to 0.99) | 0.0453 | 0.63 (0.28 to 1.44) | 0.2742 |
| Hispanic | 0.82 (0.69 to 0.99) | 0.0363 | 0.72 (0.49 to 1.06) | 0.0918 | 1.55 (1.01 to 2.38) | 0.0440 | 0.93 (0.47 to 1.84) | 0.8350 | 0.54 (0.22 to 1.32) | 0.1787 |
| Other | 0.72 (0.58 to 0.90) | 0.0039 | 1.28 (0.84 to 1.95) | 0.2555 | 1.17 (0.61 to 2.23) | 0.6341 | 0.94 (0.51 to 1.73) | 0.8414 | 0.44 (0.20 to 0.99) | 0.0461 |
| Education | ||||||||||
| <High school | 1 | 1 | 1 | 1 | 1 | |||||
| High school graduate | 1.22 (0.96 to 1.55) | 0.1129 | 1.29 (0.77 to 2.16) | 0.3345 | 0.39 (0.22 to 0.69) | 0.0012 | 0.67 (0.20 to 2.29) | 0.5269 | 6.59 (1.03 to 42.20) | 0.0467 |
| Some college | 1.36 (1.07 to 1.73) | 0.0119 | 1.75 (1.04 to 2.93) | 0.0341 | 0.59 (0.34 to 1.00) | 0.0519 | 1.02 (0.32 to 3.25) | 0.9762 | 8.50 (1.35 to 53.59) | 0.0227 |
| Bachelor degree | 1.51 (1.17 to 1.96) | 0.0017 | 1.46 (0.84 to 2.55) | 0.1850 | 0.45 (0.25 to 0.81) | 0.0071 | 0.87 (0.27 to 2.83) | 0.8226 | 6.78 (1.08 to 42.52) | 0.0412 |
| Any post college | 1.24 (0.94 to 1.63) | 0.1287 | 1.70 (0.88 to 3.28) | 0.1139 | 0.56 (0.29 to 1.08) | 0.0851 | 1.14 (0.32 to 4.06) | 0.8348 | 5.32 (0.73 to 38.82) | 0.0990 |
| Income | ||||||||||
| <20K | 1 | 1 | 1 | 1 | 1 | |||||
| 20–34.9K | 1.00 (0.83 to 1.20) | 0.9791 | 1.22 (0.88 to 1.69) | 0.2322 | 1.26 (0.73 to 2.19) | 0.4063 | 1.69 (0.80 to 3.57) | 0.1661 | 1.00 (0.48 to 2.09) | 0.9945 |
| 35–49.9K | 1.06 (0.88 to 1.28) | 0.5534 | 1.38 (0.98 to 1.95) | 0.0647 | 0.86 (0.51 to 1.45) | 0.5697 | 1.28 (0.62 to 2.65) | 0.4972 | 1.01 (0.46 to 2.21) | 0.9781 |
| 50–74.9K | 1.00 (0.84 to 1.20) | 0.9889 | 1.73 (1.25 to 2.39) | 0.0009 | 1.15 (0.74 to 1.80) | 0.5336 | 1.50 (0.88 to 2.58) | 0.1404 | 1.20 (0.61 to 2.37) | 0.5944 |
| 75–124.9K | 0.91 (0.76 to 1.08) | 0.2731 | 1.46 (1.03 to 2.06) | 0.0314 | 1.12 (0.66 to 1.91) | 0.6701 | 2.25 (1.26 to 4.02) | 0.0063 | 1.97 (0.92 to 4.22) | 0.0795 |
| 125K+ | 0.86 (0.69 to 1.08) | 0.1922 | 0.89 (0.55 to 1.43) | 0.6217 | 0.82 (0.40 to 1.67) | 0.5904 | 1.29 (0.54 to 3.09) | 0.5642 | 2.34 (0.83 to 6.63) | 0.1096 |
| LGB | ||||||||||
| No | 1 | 1 | 1 | 1 | 1 | |||||
| Yes | 0.96 (0.77 to 1.20) | 0.7236 | 1.39 (0.94 to 2.06) | 0.1045 | 1.63 (1.01 to 2.65) | 0.0463 | 2.29 (1.31 to 4.02) | 0.0038 | 0.95 (0.49 to 1.81) | 0.8669 |
| Use social media | ||||||||||
| No | 1 | 1 | 1 | 1 | 1 | |||||
| Yes | 1.33 (1.14 to 1.55) | 0.0003 | 2.29 (1.48 to 3.54) | 0.0002 | 1.37 (0.65 to 2.88) | 0.4121 | 1.69 (0.67 to 4.24) | 0.2661 | 1.11 (0.25 to 4.88) | 0.8936 |
| Average daily hours on internet | 1.02 (1.00 to 1.04) | 0.0321 | 1.05 (1.03 to 1.07) | <0.0001 | 1.05 (1.02 to 1.08) | 0.0021 | 1.08 (1.04 to 1.12) | 0.0002 | 1.06 (1.01 to 1.11) | 0.0117 |
| Observations | 16 796 | 16 796 | 16 796 | 8568 | 1409 | |||||
| No. of yes | 8568 | 1409 | 494 | 264 | 226 | |||||
LGB, lesbian, gay, and bisexual.
Association between current e-cigarette use status and media platforms
| Exposure platforms | Search platforms | Sharing platforms | |||||||
|---|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | p Value | OR (95% CI) | p Value | OR (95% CI) | p Value | ||||
| Regular television | 0.90 (0.70 to 1.16) | 0.4209 | Word of mouth | 2.60 (1.03 to 6.58) | 0.0432 | ||||
| Radio | 1.25 (0.92 to 1.70) | 0.1612 | Text message | 2.40 (0.87 to 6.65) | 0.0922 | ||||
| TV viewing sites like Hulu | 1.69 (1.00 to 2.87) | 0.0518 | |||||||
| 7.75 (3.41 to 17.61) | <0.0001 | 0.84 (0.31 to 2.29) | 0.7347 | 1.22 (0.43 to 3.47) | 0.7140 | ||||
| 1.73 (1.21 to 2.46) | 0.0025 | 3.35 (1.65 to 6.81) | 0.0009 | 4.68 (1.87 to 11.72) | 0.0010 | ||||
| YouTube/video sharing sites | 1.14 (0.69 to 1.87) | 0.6087 | YouTube/ video sharing sites | 1.96 (0.77 to 4.99) | 0.1581 | YouTube/ video sharing sites) | 1.35 (0.51 to 3.57) | 0.5443 | |
| Tumblr/blogging sites | 1.58 (0.36 to 6.87) | 0.5404 | Tumblr/blogging sites | 2.01 (0.64 to 6.36) | 0.2336 | Tumblr/blogging sites | 1.44 (0.33 to 6.39) | 0.6297 | |
| 1.53 (1.11 to 2.11) | 0.0096 | 1.42 (0.60 to 3.37) | 0.4217 | ||||||
| Internet search engines | 2.79 (2.03 to 3.85) | <0.0001 | Internet search engines | 0.93 (0.45 to 1.95) | 0.8508 | ||||
| Online news sources | 0.67 (0.44 to 1.04) | 0.0716 | Online news sources | 1.31 (0.65 to 2.64) | 0.4537 | ||||
| Other social networks | 1.00 (0.36 to 2.79) | 0.9936 | Other social networks | 0.59 (0.15 to 2.24) | 0.4340 | Other social networks | 1.57 (0.27 to 9.19) | 0.6185 | |
| Banner ads on any other website | 0.70 (0.50 to 0.99) | 0.0425 | |||||||
| Age | Age | Age | |||||||
| 18–24 | 1 | 18–24 | 1 | 18–24 | 1 | ||||
| 25–44 | 0.78 (0.53 to 1.14) | 0.1998 | 25–44 | 1.35 (0.65 to 2.78) | 0.4183 | 25–44 | 2.08 (0.78 to 5.60) | 0.1455 | |
| 45–64 | 0.75 (0.50 to 1.12) | 0.1570 | 45–64 | 0.95 (0.44 to 2.06) | 0.8948 | 45–64 | 1.13 (0.37 to 3.49) | 0.8303 | |
| 65+ | 0.45 (0.25 to 0.81) | 0.0076 | 65+ | 0.63 (0.24 to 1.67) | 0.3508 | 65+ | 0.23 (0.06 to 0.93) | 0.0394 | |
| Gender | Gender | Gender | |||||||
| Male | 1 | Male | 1 | Male | 1 | ||||
| Female | 0.88 (0.69 to 1.14) | 0.3295 | Female | 0.51 (0.31 to 0.81) | 0.0049 | Female | 0.36 (0.17 to 0.78) | 0.0098 | |
| Race | Race | Race | |||||||
| White | 1 | White | 1 | White | 1 | ||||
| Black | 0.55 (0.34 to 0.89) | 0.0147 | Black | 0.49 (0.21 to 1.14) | 0.0991 | Black | 0.46 (0.16 to 1.36) | 0.1621 | |
| Hispanic | 0.82 (0.55 to 1.25) | 0.3572 | Hispanic | 0.65 (0.26 to 1.63) | 0.3578 | Hispanic | 0.69 (0.24 to 2.00) | 0.4881 | |
| Other | 0.97 (0.64 to 1.49) | 0.9046 | Other | 1.19 (0.51 to 2.81) | 0.6876 | Other | 0.91 (0.27 to 3.10) | 0.8831 | |
| Education | Education | Education | |||||||
| <High school | 1 | <High school | 1 | <High school | 1 | ||||
| High school graduate | 1.11 (0.65 to 1.88) | 0.7076 | High school graduate | 0.28 (0.10 to 0.81) | 0.0195 | High school graduate | 0.52 (0.12 to 2.17) | 0.3650 | |
| Some college | 1.11 (0.66 to 1.87) | 0.6918 | Some college | 0.22 (0.08 to 0.63) | 0.0047 | Some college | 1.02 (0.27 to 3.84) | 0.9788 | |
| Bachelor degree | 0.68 (0.38 to 1.22) | 0.1971 | Bachelor degree | 0.27 (0.09 to 0.80) | 0.0180 | Bachelor degree | 0.53 (0.13 to 2.20) | 0.3788 | |
| Any post college | 0.42 (0.21 to 0.83) | 0.0121 | Any post college | 0.16 (0.04 to 0.67) | 0.0117 | Any post college | 1.16 (0.20 to 6.82) | 0.8731 | |
| Income | Income | Income | |||||||
| <20K | 1 | <20K | 1 | <20K | 1 | ||||
| 20–34.9K | 1.40 (0.92 to 2.13) | 0.1203 | 20 to 34.9K | 1.55 (0.74 to 3.26) | 0.2494 | 20–34.9K | 1.19 (0.38 to 3.66) | 0.7677 | |
| 35–49.9K | 1.12 (0.72 to 1.75) | 0.6163 | 35–49.9K | 0.81 (0.38 to 1.76) | 0.5990 | 35–49.9K | 1.49 (0.43 to 5.10) | 0.5278 | |
| 50–74.9K | 1.15 (0.76 to 1.75) | 0.5014 | 50–74.9K | 1.26 (0.60 to 2.64) | 0.5490 | 50–74.9K | 0.71 (0.23 to 2.20) | 0.5470 | |
| 75–124.9K | 0.96 (0.63 to 1.46) | 0.8366 | 75–124.9K | 1.58 (0.70 to 3.57) | 0.2676 | 75–124.9K | 0.79 (0.24 to 2.60) | 0.7005 | |
| 125K+ | 1.23 (0.68 to 2.24) | 0.4929 | 125K+ | 2.80 (0.84 to 9.30) | 0.0928 | 125K+ | 28.70 (2.86 to 288.30) | 0.0043 | |
| LGB | LGB | LGB | |||||||
| No | 1 | No | 1 | No | 1 | ||||
| Yes | 1.13 (0.72 to 1.76) | 0.6020 | Yes | 0.61 (0.30 to 1.24) | 0.1713 | Yes | 0.57 (0.15 to 2.26) | 0.4278 | |
| Use Social Media | Use social media | Use social media | |||||||
| No | 1 | No | 1 | No | 1 | ||||
| Yes | 1.39 (0.78 to 2.49) | 0.2645 | Yes | 0.54 (0.15 to 1.91) | 0.3404 | Yes | 5.31 (0.97 to 28.94) | 0.0537 | |
| Daily hours on internet | 1.06 (1.04 to 1.09) | <0.0001 | Daily hours on internet | 1.00 (0.95 to 1.06) | 0.9871 | Daily hours on internet | 1.02 (0.95 to 1.10) | 0.5870 | |
| Observations | 5644 | Observations | 773 | Observations | 345 | ||||
LGB, lesbian, gay, and bisexual.
Media platforms for seeing/hearing, searching and sharing e-cigarette-related information
| Overall (%) | Among e-cig users (%) | Among non-e-cig users (%) | Un-adj OR (95% CI) | χ2 p Value | |
|---|---|---|---|---|---|
| Seen/heard platforms (n=5906) | |||||
| Regular television | 66.1 (64.2–68.1) | 59.6 (54.8–64.5) | 66.8 (64.7–68.9) | 0.73 (0.59 to 0.92) | 0.0065 |
| Radio | 19.2 (17.6–20.8) | 25.9 (21.3–30.5) | 18.5 (16.8–20.3) | 1.53 (1.18 to 2.00) | 0.0014 |
| Banner ads on any other website | 14.1 (12.7–15.6) | 14.5 (11.3–17.8) | 14.0 (12.5–15.6) | 1.04 (0.78 to 1.39) | 0.7852 |
| 13.3 (12.1–14.6) | 25.5 (21.3–29.6) | 12.1 (10.8–13.4) | 2.48 (1.93 to 3.18) | <0.0001 | |
| Internet search engines | 11.1 (9.9–12.3) | 26.9 (22.4–31.3) | 9.5 (8.3–10.7) | 3.50 (2.67 to 4.58) | <0.0001 |
| 8.6 (7.6–9.7) | 22.2 (18.3–26.1) | 7.3 (6.3–8.3) | 3.64 (2.78 to 4.78) | <0.0001 | |
| Online news sources | 8.1 (7.0–9.2) | 10.2 (7.7–12.6) | 7.9 (6.8–9.1) | 1.31 (0.96 to 1.79) | 0.0886 |
| YouTube (and other video sharing sites) | 3.8 (3.0–4.5) | 10.8 (8.3–13.4) | 3.1 (2.3–3.8) | 3.86 (2.66 to 5.60) | <0.0001 |
| Television viewing websites like Hulu | 3.0 (2.4–3.6) | 7.9 (5.8–10.0) | 2.5 (1.9–3.1) | 3.37 (2.28 to 4.97) | <0.0001 |
| Some other social network (specify) | 2.2 (1.6–2.9) | 1.7 (0.2–3.3) | 2.3 (1.6–3.0) | 0.75 (0.29 to 1.94) | 0.5524 |
| 1.2 (0.9–1.5) | 7.7 (5.5–9.9) | 0.5 (0.3–0.7) | 16.97 (9.52 to 30.27) | <0.0001 | |
| Tumblr (and other blogging sites, like blogger) | 0.5 (0.3–0.7) | 2.7 (1.4–4.0) | 0.3 (0.1–0.5) | 9.41 (4.41 to 20.07) | <0.0001 |
| Searched platforms (n=799) | |||||
| Internet search engines | 79.9 (75.2–84.7) | 75.6 (69.2–82.0) | 84.8 (77.9–91.8) | 0.55 (0.29 to 1.05) | 0.0694 |
| 15.5 (12.1–18.8) | 22.9 (17.5–28.4) | 7.0 (4.0–10.0) | 3.95 (2.26 to 6.91) | <0.0001 | |
| Online news sources | 12.0 (8.9–15.1) | 13.4 (9.3–17.5) | 10.4 (5.6–15.2) | 1.33 (0.72 to 2.48) | 0.3617 |
| YouTube (and other video sharing sites) | 11.4 (7.9–14.8) | 15.8 (11.4–20.2) | 6.4 (0.7–12.0) | 2.76 (1.01 to 7.50) | 0.0429 |
| 6.6 (4.5–8.6) | 9.1 (6.0–12.2) | 3.7 (1.2–6.2) | 2.62 (1.17 to 5.84) | 0.015 | |
| Tumblr (and other blogging sites, like blogger) | 5.8 (3.2–8.4) | 8.5 (3.9–13.0) | 2.9 (1.0–4.7) | 3.14 (1.29 to 7.65) | 0.0069 |
| Some other social network (specify) | 1.8 (0.8–2.7) | 1.4 (0.2–2.5) | 2.2 (0.6–3.8) | 0.61 (0.20 to 1.89) | 0.3897 |
| Shared platforms (n=363) | |||||
| Word of mouth | 53.9 (45.2–62.6) | 54.4 (45.1–63.7) | 53.6 (38.9–68.2) | 1.03 (0.51 to 2.08) | 0.9262 |
| 33.2 (26.2–40.2) | 48.5 (39.1–57.9) | 18.3 (10.6–25.9) | 4.22 (2.23 to 7.98) | <0.0001 | |
| Text message | 24.2 (16.7–31.6) | 31.8 (22.9–40.7) | 16.9 (5.1–28.6) | 2.30 (0.90 to 5.86) | 0.0769 |
| 22.4 (16.1–28.8) | 26.8 (18.6–35.0) | 18.3 (8.9–27.7) | 1.63 (0.77 to 3.48) | 0.1932 | |
| 11.8 (7.9–15.7) | 17.2 (11.1–23.2) | 6.5 (2.1–10.8) | 3.01 (1.30 to 6.97) | 0.0059 | |
| YouTube (and other video sharing sites) | 10.9 (6.6–15.3) | 14.0 (8.5–19.6) | 7.9 (1.3–14.6) | 1.90 (0.69 to 5.27) | 0.2076 |
| Tumblr (and other blogging sites, like blogger) | 8.7 (3.6–13.8) | 11.4 (6.6–16.2) | 6.1 (0.0–15.1) | 1.99 (0.38 to 10.44) | 0.4132 |
| Some other social network (specify) | 3.9 (0.0–7.7) | 3.5 (0.0–7.3) | 4.2 (0.0–10.8) | 0.81 (0.11 to 5.93) | 0.8378 |