PURPOSE: To evaluate the diagnostic performance of a newly developed non-contrast-enhanced MR angiography (NCE-MRA) technique using flow-sensitive dephasing (FSD) prepared steady-state free precession (SSFP) for detecting calf arterial disease in patients with diabetes. MATERIALS AND METHODS: Forty-five patients with diabetes who underwent routine contrast-enhanced MR angiography (CE-MRA) of lower extremities were recruited for NCE-MRA at the calf on a 1.5 Tesla MR system. Image quality evaluated on a 4-point scale and diagnostic performance for detecting more than 50% arterial stenosis were statistically analyzed, using CE-MRA as the standard of reference. RESULTS: A total of 264 calf arterial segments were obtained in the 45 patients with 88 legs. The percentage of diagnostic arterial segments was all 98% for NCE- and CE-MRA. The image quality, SNR, CNR was 3.3, 177, 138, and 3.5, 103, 99, for NCE-MRA and CE-MRA, respectively. The average sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of NCE-MRA were 97%, 96%, 90%, 99%, and 96%, respectively on a per-segment basis and 90%, 84%, 82%, 91%, and 87%, respectively, on a per-patients basis. CONCLUSION: The NCE-MRA technique demonstrates adequate image quality in the delineation of calf arteries and consistent diagnostic performance for detecting significant stenosis with CE-MRA in patients with diabetes.
PURPOSE: To evaluate the diagnostic performance of a newly developed non-contrast-enhanced MR angiography (NCE-MRA) technique using flow-sensitive dephasing (FSD) prepared steady-state free precession (SSFP) for detecting calf arterial disease in patients with diabetes. MATERIALS AND METHODS: Forty-five patients with diabetes who underwent routine contrast-enhanced MR angiography (CE-MRA) of lower extremities were recruited for NCE-MRA at the calf on a 1.5 Tesla MR system. Image quality evaluated on a 4-point scale and diagnostic performance for detecting more than 50% arterial stenosis were statistically analyzed, using CE-MRA as the standard of reference. RESULTS: A total of 264 calf arterial segments were obtained in the 45 patients with 88 legs. The percentage of diagnostic arterial segments was all 98% for NCE- and CE-MRA. The image quality, SNR, CNR was 3.3, 177, 138, and 3.5, 103, 99, for NCE-MRA and CE-MRA, respectively. The average sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of NCE-MRA were 97%, 96%, 90%, 99%, and 96%, respectively on a per-segment basis and 90%, 84%, 82%, 91%, and 87%, respectively, on a per-patients basis. CONCLUSION: The NCE-MRA technique demonstrates adequate image quality in the delineation of calf arteries and consistent diagnostic performance for detecting significant stenosis with CE-MRA in patients with diabetes.
Authors: Philip A Hodnett; Emily V Ward; Amir H Davarpanah; Timothy G Scanlon; Jeremy D Collins; Christopher B Glielmi; Xiaoming Bi; Ioannis Koktzoglou; Navyash Gupta; James C Carr; Robert R Edelman Journal: AJR Am J Roentgenol Date: 2011-12 Impact factor: 3.959
Authors: Philip A Hodnett; Ioannis Koktzoglou; Amir H Davarpanah; Timothy G Scanlon; Jeremy D Collins; John J Sheehan; Eugene E Dunkle; Navyash Gupta; James C Carr; Robert R Edelman Journal: Radiology Date: 2011-04-18 Impact factor: 11.105
Authors: Rolf Wyttenbach; Antonio Braghetti; Michael Wyss; Mario Alerci; Lukas Briner; Paolo Santini; Luca Cozzi; Marcello Di Valentino; Marcus Katoh; Claudio Marone; Peter Vock; Augusto Gallino Journal: Radiology Date: 2007-08-23 Impact factor: 11.105
Authors: Fernanda Garozzo Velloni; Patrícia Prando Cardia; Ulysses Dos Santos Torres; Marco Antonio Haddad Pereira; Thiago José Penachim; Larissa Rossini Favaro; Miguel Ramalho; Giuseppe D'Ippolito Journal: Radiol Bras Date: 2020 Jul-Aug