Literature DB >> 24910149

Real-time processing in picture naming in adults who stutter: ERP evidence.

Nathan D Maxfield1, Kalie Morris2, Stefan A Frisch2, Kathryn Morphew2, Joseph L Constantine2.   

Abstract

OBJECTIVE: The aim was to compare real-time language/cognitive processing in picture naming in adults who stutter (AWS) versus typically-fluent adults (TFA).
METHODS: Participants named pictures preceded by masked prime words. Primes and target picture labels were identical or mismatched. Priming effects on naming and picture-elicited ERP activity were analyzed. Vocabulary knowledge correlations with these measures were assessed.
RESULTS: Priming improved naming RTs and accuracy in both groups. RTs were longer for AWS, and correlated positively with receptive vocabulary in TFA. Electrophysiologically, posterior-P1 amplitude negatively correlated with expressive vocabulary in TFA versus receptive vocabulary in AWS. Frontal/temporal-P1 amplitude correlated positively with expressive vocabulary in AWS. Identity priming enhanced frontal/posterior-N2 amplitude in both groups, and attenuated P280 amplitude in AWS. N400 priming was topographically-restricted in AWS.
CONCLUSIONS: Results suggest that conceptual knowledge was perceptually-grounded in expressive vocabulary in TFA versus receptive vocabulary in AWS. Poorer expressive vocabulary in AWS was potentially associated with greater suppression of irrelevant conceptual information. Priming enhanced N2-indexed cognitive control and visual attention in both groups. P280-indexed focal attention attenuated with priming in AWS only. Topographically-restricted N400 priming suggests that lemma/word form connections were weaker in AWS. SIGNIFICANCE: Real-time language/cognitive processing in picture naming operates differently in AWS.
Copyright © 2014 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Attention; Event-related potentials; Lexical; Picture naming; Stuttering

Mesh:

Year:  2014        PMID: 24910149      PMCID: PMC4239194          DOI: 10.1016/j.clinph.2014.05.009

Source DB:  PubMed          Journal:  Clin Neurophysiol        ISSN: 1388-2457            Impact factor:   3.708


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