Literature DB >> 24898747

Human stem cells for modeling heart disease and for drug discovery.

Elena Matsa1, Paul W Burridge1, Joseph C Wu2.   

Abstract

A major research focus in the field of cardiovascular medicine is the prospect of using stem cells and progenitor cells for cardiac regeneration. With the advent of induced pluripotent stem cell (iPSC) technology, major efforts are also underway to use iPSCs to model heart disease, to screen for new drugs, and to test candidate drugs for cardiotoxicity. Here, we discuss recent advances in the exciting fields of stem cells and cardiovascular disease.
Copyright © 2014, American Association for the Advancement of Science.

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Year:  2014        PMID： 24898747      PMCID： PMC4215696          DOI： 10.1126/scitranslmed.3008921

Source DB:  PubMed          Journal:  Sci Transl Med        ISSN： 1946-6234            Impact factor:   17.956


  55 in total

Review 1.  Cardiomyogenic stem and progenitor cell plasticity and the dissection of cardiopoiesis.

Authors:  Maria Grazia Perino; Satoshi Yamanaka; Jinliang Li; Anna M Wobus; Kenneth R Boheler
Journal:  J Mol Cell Cardiol       Date:  2008-05-11       Impact factor: 5.000

2.  Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes.

Authors:  I Kehat; D Kenyagin-Karsenti; M Snir; H Segev; M Amit; A Gepstein; E Livne; O Binah; J Itskovitz-Eldor; L Gepstein
Journal:  J Clin Invest       Date:  2001-08       Impact factor: 14.808

3.  Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function.

Authors:  A A Kocher; M D Schuster; M J Szabolcs; S Takuma; D Burkhoff; J Wang; S Homma; N M Edwards; S Itescu
Journal:  Nat Med       Date:  2001-04       Impact factor: 53.440

4.  Induction of pluripotent stem cells from adult human fibroblasts by defined factors.

Authors:  Kazutoshi Takahashi; Koji Tanabe; Mari Ohnuki; Megumi Narita; Tomoko Ichisaka; Kiichiro Tomoda; Shinya Yamanaka
Journal:  Cell       Date:  2007-11-30       Impact factor: 41.582

5.  Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts.

Authors:  Michael A Laflamme; Kent Y Chen; Anna V Naumova; Veronica Muskheli; James A Fugate; Sarah K Dupras; Hans Reinecke; Chunhui Xu; Mohammad Hassanipour; Shailaja Police; Chris O'Sullivan; Lila Collins; Yinhong Chen; Elina Minami; Edward A Gill; Shuichi Ueno; Chun Yuan; Joseph Gold; Charles E Murry
Journal:  Nat Biotechnol       Date:  2007-08-26       Impact factor: 54.908

6.  Embryoid body morphology influences diffusive transport of inductive biochemicals: a strategy for stem cell differentiation.

Authors:  Eleftherios Sachlos; Debra T Auguste
Journal:  Biomaterials       Date:  2008-09-14       Impact factor: 12.479

7.  Highly efficient induction and long-term maintenance of multipotent cardiovascular progenitors from human pluripotent stem cells under defined conditions.

Authors:  Nan Cao; He Liang; Jijun Huang; Jia Wang; Yixiong Chen; Zhongyan Chen; Huang-Tian Yang
Journal:  Cell Res       Date:  2013-07-30       Impact factor: 25.617

8.  Human embryonic stem cells develop into multiple types of cardiac myocytes: action potential characterization.

Authors:  Jia-Qiang He; Yue Ma; Youngsook Lee; James A Thomson; Timothy J Kamp
Journal:  Circ Res       Date:  2003-06-05       Impact factor: 17.367

9.  Direct reprogramming of human fibroblasts toward a cardiomyocyte-like state.

Authors:  Ji-Dong Fu; Nicole R Stone; Lei Liu; C Ian Spencer; Li Qian; Yohei Hayashi; Paul Delgado-Olguin; Sheng Ding; Benoit G Bruneau; Deepak Srivastava
Journal:  Stem Cell Reports       Date:  2013-08-22       Impact factor: 7.765

10.  c-kit+ cells minimally contribute cardiomyocytes to the heart.

Authors:  Jop H van Berlo; Onur Kanisicak; Marjorie Maillet; Ronald J Vagnozzi; Jason Karch; Suh-Chin J Lin; Ryan C Middleton; Eduardo Marbán; Jeffery D Molkentin
Journal:  Nature       Date:  2014-05-07       Impact factor: 49.962
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  81 in total

1.  Pravastatin reverses obesity-induced dysfunction of induced pluripotent stem cell-derived endothelial cells via a nitric oxide-dependent mechanism.

Authors:  Mingxia Gu; Nicholas M Mordwinkin; Nigel G Kooreman; Jaecheol Lee; Haodi Wu; Shijun Hu; Jared M Churko; Sebastian Diecke; Paul W Burridge; Chunjiang He; Frances E Barron; Sang-Ging Ong; Joseph D Gold; Joseph C Wu
Journal:  Eur Heart J       Date:  2014-11-02       Impact factor: 29.983

Review 2.  Stem cells: An eventual treatment option for heart diseases.

Authors:  Joseph C Bilgimol; Subbareddy Ragupathi; Lakshmanan Vengadassalapathy; Nathan S Senthil; Kalimuthu Selvakumar; M Ganesan; Sadananda Rao Manjunath
Journal:  World J Stem Cells       Date:  2015-09-26       Impact factor: 5.326

Review 3.  Engineered heart tissues and induced pluripotent stem cells: Macro- and microstructures for disease modeling, drug screening, and translational studies.

Authors:  Evangeline Tzatzalos; Oscar J Abilez; Praveen Shukla; Joseph C Wu
Journal:  Adv Drug Deliv Rev       Date:  2015-09-30       Impact factor: 15.470

Review 4.  Modern stem cell therapy: approach to disease.

Authors:  Mateja Zemljic; Bozena Pejkovic; Ivan Krajnc; Lidija Kocbek
Journal:  Wien Klin Wochenschr       Date:  2015-12-10       Impact factor: 1.704

5.  Making cardiomyocytes with your chemistry set: Small molecule-induced cardiogenesis in somatic cells.

Authors:  Woong-Hee Kim; Da-Woon Jung; Darren Reece Williams
Journal:  World J Cardiol       Date:  2015-03-26

6.  Large Animal Models of Ischemic Cardiomyopathy: Are They Enough to Bridge the Translational Gap?

Authors:  Patricia K Nguyen; Joseph C Wu
Journal:  J Nucl Cardiol       Date:  2015-08       Impact factor: 5.952

7.  Inspiration from heart development: Biomimetic development of functional human cardiac organoids.

Authors:  Dylan J Richards; Robert C Coyle; Yu Tan; Jia Jia; Kerri Wong; Katelynn Toomer; Donald R Menick; Ying Mei
Journal:  Biomaterials       Date:  2017-07-12       Impact factor: 12.479

Review 8.  Induced pluripotent stem cells for cardiovascular disease: from product-focused disease modeling to process-focused disease discovery.

Authors:  Katherine A Campbell; Andre Terzic; Timothy J Nelson
Journal:  Regen Med       Date:  2015-10-06       Impact factor: 3.806

9.  Contractile work directly modulates mitochondrial protein levels in human engineered heart tissues.

Authors:  Ronald Ng; Lorenzo R Sewanan; Allison L Brill; Paul Stankey; Xia Li; Yibing Qyang; Barbara E Ehrlich; Stuart G Campbell
Journal:  Am J Physiol Heart Circ Physiol       Date:  2020-05-08       Impact factor: 4.733

Review 10.  Translation of Human-Induced Pluripotent Stem Cells: From Clinical Trial in a Dish to Precision Medicine.

Authors:  Nazish Sayed; Chun Liu; Joseph C Wu
Journal:  J Am Coll Cardiol       Date:  2016-05-10       Impact factor: 24.094
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