| Literature DB >> 26435771 |
Joseph C Bilgimol1, Subbareddy Ragupathi1, Lakshmanan Vengadassalapathy1, Nathan S Senthil1, Kalimuthu Selvakumar1, M Ganesan1, Sadananda Rao Manjunath1.
Abstract
Stem cells are of global excitement for various diseases including heart diseases. It is worth to understand the mechanism or role of stem cells in the treatment of heart failure. Bone marrow derived stem cells are commonly practiced with an aim to improve the function of the heart. The majority of studies have been conducted with acute myocardial infarction and a few has been investigated with the use of stem cells for treating chronic or dilated cardiomyopathy. Heterogeneity in the treated group using stem cells has greatly emerged. Ever increasing demand for any alternative made is of at most priority for cardiomyopathy. Stem cells are of top priority with the current impact that has generated among physicians. However, meticulous selection of proper source is required since redundancy is clearly evident with the present survey. This review focuses on the methods adopted using stem cells for heart diseases and outcomes that are generated so far with an idea to determine the best therapeutic possibility in order to fulfill the present demand.Entities:
Keywords: Bone marrow stem cells; Heart diseases; Induced pluripotent stem cells; Mesenchymal stem cells; Progenitor cells; Stem cells
Year: 2015 PMID： 26435771 PMCID： PMC4591785 DOI： 10.4252/wjsc.v7.i8.1118
Source DB: PubMed Journal: World J Stem Cells ISSN： 1948-0210 Impact factor: 5.326