| Literature DB >> 24884816 |
Ilaria Tirotta1, Alfonso Mastropietro, Chiara Cordiglieri, Lara Gazzera, Fulvio Baggi, Giuseppe Baselli, Maria Grazia Bruzzone, Ileana Zucca, Gabriella Cavallo, Giancarlo Terraneo, Francesca Baldelli Bombelli, Pierangelo Metrangolo, Giuseppe Resnati.
Abstract
(19)F-MRI offers unique opportunities to image diseases and track cells and therapeutic agents in vivo. Herein we report a superfluorinated molecular probe, herein called PERFECTA, possessing excellent cellular compatibility, and whose spectral properties, relaxation times, and sensitivity are promising for in vivo (19)F-MRI applications. The molecule, which bears 36 equivalent (19)F atoms and shows a single intense resonance peak, is easily synthesized via a simple one-step reaction and is formulated in water with high stability using trivial reagents and methods.Entities:
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Year: 2014 PMID： 24884816 DOI： 10.1021/ja503270n
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419