OBJECTIVES: Beyond oncological safety, consideration of 30-day complications according to Clavien-Dindo, as well as postoperative quality of life (QoL) after nephron-sparing surgery for clinical T1 renal masses, represents important factors for treatment decision counseling. The objective of this study was to compare the effect of laparoscopic versus open partial nephrectomy (LPN vs. OPN) on 30-day complications and long-term postoperative QoL for clinical T1 renal masses. METHODS: Retrospective, longitudinal analysis of 293 patients treated with either LPN versus OPN for T1 renal masses. The investigated endpoints were 30-day Clavien-Dindo complications and health-related QoL (EORTC QLQ-C30). Respectively, logistic and linear regression models analyzed the effect of surgical partial nephrectomy approach on endpoints. RESULTS: Overall complication rates were similar in patients undergoing OPN or LPN (16.1 vs. 14.6 %, p = 0.8). Significantly less major complications (2.4 vs. 10.4 %, p = 0.025) occurred after LPN. Despite a shorter convalescence period for LPN patients (p = 0.035), in uni- and multivariable analyses, surgical approach was not associated with 30-day complications nor long-term differences in QoL (all p > 0.05). CONCLUSIONS: Despite a faster recovery time after LPN, our findings suggest that LPN and OPN are equivalent with regard to 30-day Clavien-Dindo complication rates and long-term QoL.
OBJECTIVES: Beyond oncological safety, consideration of 30-day complications according to Clavien-Dindo, as well as postoperative quality of life (QoL) after nephron-sparing surgery for clinical T1 renal masses, represents important factors for treatment decision counseling. The objective of this study was to compare the effect of laparoscopic versus open partial nephrectomy (LPN vs. OPN) on 30-day complications and long-term postoperative QoL for clinical T1 renal masses. METHODS: Retrospective, longitudinal analysis of 293 patients treated with either LPN versus OPN for T1 renal masses. The investigated endpoints were 30-day Clavien-Dindo complications and health-related QoL (EORTC QLQ-C30). Respectively, logistic and linear regression models analyzed the effect of surgical partial nephrectomy approach on endpoints. RESULTS: Overall complication rates were similar in patients undergoing OPN or LPN (16.1 vs. 14.6 %, p = 0.8). Significantly less major complications (2.4 vs. 10.4 %, p = 0.025) occurred after LPN. Despite a shorter convalescence period for LPN patients (p = 0.035), in uni- and multivariable analyses, surgical approach was not associated with 30-day complications nor long-term differences in QoL (all p > 0.05). CONCLUSIONS: Despite a faster recovery time after LPN, our findings suggest that LPN and OPN are equivalent with regard to 30-day Clavien-Dindo complication rates and long-term QoL.
Authors: Patricia A Parker; Richard Swartz; Bryan Fellman; Diana Urbauer; Yisheng Li; Louis L Pisters; Charles J Rosser; Christopher G Wood; Surena F Matin Journal: J Urol Date: 2012-01-15 Impact factor: 7.450
Authors: Marco Bianchi; Andreas Becker; Firas Abdollah; Quoc-Dien Trinh; Jens Hansen; Zhe Tian; Shahrokh F Shariat; Paul Perrotte; Pierre I Karakiewicz; Maxine Sun Journal: Int J Urol Date: 2013-02-19 Impact factor: 3.369
Authors: M Sun; F Abdollah; S F Shariat; J Schmitges; Q-D Trinh; Z Tian; C Jeldres; A Abdo; M Bianchi; A Briganti; F Montorsi; P Perrotte; P I Karakiewicz Journal: Eur J Surg Oncol Date: 2011-10-13 Impact factor: 4.424
Authors: Christian Gratzke; Michael Seitz; Florian Bayrle; Boris Schlenker; Patrick J Bastian; Niko Haseke; Markus Bader; Derya Tilki; Alexander Roosen; Alexander Karl; Oliver Reich; Wael Y Khoder; Stephen Wyler; Christian G Stief; Michael Staehler; Alexander Bachmann Journal: BJU Int Date: 2009-02-23 Impact factor: 5.588
Authors: Inderbir S Gill; Louis R Kavoussi; Brian R Lane; Michael L Blute; Denise Babineau; J Roberto Colombo; Igor Frank; Sompol Permpongkosol; Christopher J Weight; Jihad H Kaouk; Michael W Kattan; Andrew C Novick Journal: J Urol Date: 2007-05-11 Impact factor: 7.450
Authors: J C Bolger; M P Broe; M A Zarog; A Looney; K McKevitt; D Walsh; S Giri; C Peirce; J C Coffey Journal: Tech Coloproctol Date: 2017-09-19 Impact factor: 3.781
Authors: Przemysław Adamczyk; Kajetan Juszczak; Tomasz Drewa; Milan Hora; Peter Nyirády; Marek Sosnowski Journal: Cent European J Urol Date: 2016-11-30