Literature DB >> 24869902

Carbon nanotube electron field emitters for x-ray imaging of human breast cancer.

Emily Gidcumb1, Bo Gao, Jing Shan, Christy Inscoe, Jianping Lu, Otto Zhou.   

Abstract

For imaging human breast cancer, digital breast tomosynthesis (DBT) has been shown to improve image quality and breast cancer detection in comparison to two-dimensional (2D) mammography. Current DBT systems have limited spatial resolution and lengthy scan times. Stationary DBT (s-DBT), utilizing an array of carbon nanotube (CNT) field emission x-ray sources, provides increased spatial resolution and potentially faster imaging than current DBT systems. This study presents the results of detailed evaluations of CNT cathodes for x-ray breast imaging tasks. The following were investigated: high current, long-term stability of CNT cathodes for DBT; feasibility of using CNT cathodes to perform a 2D radiograph function; and cathode performance through several years of imaging. Results show that a breast tomosynthesis system using CNT cathodes could run far beyond the experimentally tested lifetime of one to two years. CNT cathodes were found capable of producing higher currents than typical DBT would require, indicating that the s-DBT imaging time can be further reduced. The feasibility of using a single cathode of the s-DBT tube to perform 2D mammography in 4 s was demonstrated. Over the lifetime of the prototype s-DBT system, it was found that both cathode performance and transmission rate were stable and consistent.

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Year:  2014        PMID: 24869902      PMCID: PMC4111146          DOI: 10.1088/0957-4484/25/24/245704

Source DB:  PubMed          Journal:  Nanotechnology        ISSN: 0957-4484            Impact factor:   3.874


  12 in total

1.  Hot nanotubes: stable heating of individual multiwall carbon nanotubes to 2000 k induced by the field-emission current.

Authors:  S T Purcell; P Vincent; C Journet; Vu Thien Binh
Journal:  Phys Rev Lett       Date:  2002-02-20       Impact factor: 9.161

Review 2.  Digital x-ray tomosynthesis: current state of the art and clinical potential.

Authors:  James T Dobbins; Devon J Godfrey
Journal:  Phys Med Biol       Date:  2003-10-07       Impact factor: 3.609

3.  Fabrication of small diameter few-walled carbon nanotubes with enhanced field emission property.

Authors:  Cheng Qian; Hang Qi; Bo Gao; Yuan Cheng; Qi Qiu; Lu-Chang Qin; Otto Zhou; Jie Liu
Journal:  J Nanosci Nanotechnol       Date:  2006-05

4.  Resolution at oblique incidence angles of a flat panel imager for breast tomosynthesis.

Authors:  James G Mainprize; Aili K Bloomquist; Michael P Kempston; Martin J Yaffe
Journal:  Med Phys       Date:  2006-09       Impact factor: 4.071

5.  Imaging performance of an amorphous selenium digital mammography detector in a breast tomosynthesis system.

Authors:  Bo Zhao; Wei Zhao
Journal:  Med Phys       Date:  2008-05       Impact factor: 4.071

Review 6.  A review of breast tomosynthesis. Part I. The image acquisition process.

Authors:  Ioannis Sechopoulos
Journal:  Med Phys       Date:  2013-01       Impact factor: 4.071

7.  Dependency of image quality on system configuration parameters in a stationary digital breast tomosynthesis system.

Authors:  Andrew W Tucker; Jianping Lu; Otto Zhou
Journal:  Med Phys       Date:  2013-03       Impact factor: 4.071

8.  Detection and classification of calcifications on digital breast tomosynthesis and 2D digital mammography: a comparison.

Authors:  M Lee Spangler; Margarita L Zuley; Jules H Sumkin; Gordan Abrams; Marie A Ganott; Christiane Hakim; Ronald Perrin; Denise M Chough; Ratan Shah; David Gur
Journal:  AJR Am J Roentgenol       Date:  2011-02       Impact factor: 3.959

9.  A carbon nanotube field emission cathode with high current density and long-term stability.

Authors:  Xiomara Calderón-Colón; Huaizhi Geng; Bo Gao; Lei An; Guohua Cao; Otto Zhou
Journal:  Nanotechnology       Date:  2009-07-21       Impact factor: 3.874

10.  Design and characterization of a spatially distributed multibeam field emission x-ray source for stationary digital breast tomosynthesis.

Authors:  Xin Qian; Ramya Rajaram; Xiomara Calderon-Colon; Guang Yang; Tuyen Phan; David S Lalush; Jianping Lu; Otto Zhou
Journal:  Med Phys       Date:  2009-10       Impact factor: 4.071

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  1 in total

1.  Design and Simulation of a Multi-Sheet Beam Terahertz Radiation Source Based on Carbon-Nanotube Cold Cathode.

Authors:  Yifan Zu; Xuesong Yuan; Xiaotao Xu; Matthew T Cole; Yu Zhang; Hailong Li; Yong Yin; Bin Wang; Yang Yan
Journal:  Nanomaterials (Basel)       Date:  2019-12-12       Impact factor: 5.076

  1 in total

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