Literature DB >> 24842106

Mitophagy mechanisms and role in human diseases.

Matthew Redmann1, Matthew Dodson1, Michaël Boyer-Guittaut2, Victor Darley-Usmar1, Jianhua Zhang3.   

Abstract

Mitophagy is a process of mitochondrial turnover through lysosomal mediated autophagy activities. This review will highlight recent studies that have identified mediators of mitophagy in response to starvation, loss of mitochondrial membrane potential or perturbation of mitochondrial integrity. Furthermore, we will review evidence of mitophagy dysfunction in various human diseases and discuss the potential for therapeutic interventions that target mitophagy processes.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Cancer; Heart disease; Mitochondria; Mitophagy; Parkinson's disease

Mesh：

Year:  2014        PMID： 24842106      PMCID： PMC4111979          DOI： 10.1016/j.biocel.2014.05.010

Source DB:  PubMed          Journal:  Int J Biochem Cell Biol        ISSN： 1357-2725            Impact factor:   5.085


  111 in total

1.  The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy.

Authors:  S Michiorri; V Gelmetti; E Giarda; F Lombardi; F Romano; R Marongiu; S Nerini-Molteni; P Sale; R Vago; G Arena; L Torosantucci; L Cassina; M A Russo; B Dallapiccola; E M Valente; G Casari
Journal:  Cell Death Differ       Date:  2010-01-08       Impact factor: 15.828

2.  Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane.

Authors:  Saori R Yoshii; Chieko Kishi; Naotada Ishihara; Noboru Mizushima
Journal:  J Biol Chem       Date:  2011-03-18       Impact factor: 5.157

Review 3.  Mitochondrial pruning by Nix and BNip3: an essential function for cardiac-expressed death factors.

Authors:  Gerald W Dorn
Journal:  J Cardiovasc Transl Res       Date:  2010-03-16       Impact factor: 4.132

Review 4.  Contribution of impaired mitochondrial autophagy to cardiac aging: mechanisms and therapeutic opportunities.

Authors:  Debapriya Dutta; Riccardo Calvani; Roberto Bernabei; Christiaan Leeuwenburgh; Emanuele Marzetti
Journal:  Circ Res       Date:  2012-04-13       Impact factor: 17.367

5.  Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart.

Authors:  Atsushi Hoshino; Yuichiro Mita; Yoshifumi Okawa; Makoto Ariyoshi; Eri Iwai-Kanai; Tomomi Ueyama; Koji Ikeda; Takehiro Ogata; Satoaki Matoba
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

6.  The scaffold protein Atg11 recruits fission machinery to drive selective mitochondria degradation by autophagy.

Authors:  Kai Mao; Ke Wang; Xu Liu; Daniel J Klionsky
Journal:  Dev Cell       Date:  2013-06-27       Impact factor: 12.270

7.  High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.

Authors:  Samuel A Hasson; Lesley A Kane; Koji Yamano; Chiu-Hui Huang; Danielle A Sliter; Eugen Buehler; Chunxin Wang; Sabrina M Heman-Ackah; Tara Hessa; Rajarshi Guha; Scott E Martin; Richard J Youle
Journal:  Nature       Date:  2013-11-24       Impact factor: 49.962

8.  Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue.

Authors:  Yoichi Imaizumi; Yohei Okada; Wado Akamatsu; Masato Koike; Naoko Kuzumaki; Hideki Hayakawa; Tomoko Nihira; Tetsuro Kobayashi; Manabu Ohyama; Shigeto Sato; Masashi Takanashi; Manabu Funayama; Akiyoshi Hirayama; Tomoyoshi Soga; Takako Hishiki; Makoto Suematsu; Takuya Yagi; Daisuke Ito; Arifumi Kosakai; Kozo Hayashi; Masanobu Shouji; Atsushi Nakanishi; Norihiro Suzuki; Yoshikuni Mizuno; Noboru Mizushima; Masayuki Amagai; Yasuo Uchiyama; Hideki Mochizuki; Nobutaka Hattori; Hideyuki Okano
Journal:  Mol Brain       Date:  2012-10-06       Impact factor: 4.041

9.  AF-6 is a positive modulator of the PINK1/parkin pathway and is deficient in Parkinson's disease.

Authors:  Joseph Haskin; Raymonde Szargel; Vered Shani; Lucy N Mekies; Ruth Rott; Grace G Y Lim; Kah-Leong Lim; Rina Bandopadhyay; Herman Wolosker; Simone Engelender
Journal:  Hum Mol Genet       Date:  2013-02-07       Impact factor: 6.150

10.  The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy.

Authors:  Victoria S Burchell; David E Nelson; Alvaro Sanchez-Martinez; Marta Delgado-Camprubi; Rachael M Ivatt; Joe H Pogson; Suzanne J Randle; Selina Wray; Patrick A Lewis; Henry Houlden; Andrey Y Abramov; John Hardy; Nicholas W Wood; Alexander J Whitworth; Heike Laman; Helene Plun-Favreau
Journal:  Nat Neurosci       Date:  2013-08-11       Impact factor: 24.884
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  52 in total

1.  Mitophagy in Refractory Temporal Lobe Epilepsy Patients with Hippocampal Sclerosis.

Authors:  Mengqian Wu; Xinyu Liu; Xiaosa Chi; Le Zhang; Weixi Xiong; Siew Mun Vance Chiang; Dong Zhou; Jinmei Li
Journal:  Cell Mol Neurobiol       Date:  2017-04-12       Impact factor: 5.046

2.  Sulfuretin protects hepatic cells through regulation of ROS levels and autophagic flux.

Authors:  Yu-Ting Lu; Yu-Feng Xiao; Yu-Feng Li; Jia Li; Fa-Jun Nan; Jing-Ya Li
Journal:  Acta Pharmacol Sin       Date:  2018-12-18       Impact factor: 6.150

3.  PHB2 (prohibitin 2) promotes PINK1-PRKN/Parkin-dependent mitophagy by the PARL-PGAM5-PINK1 axis.

Authors:  Chaojun Yan; Longlong Gong; Li Chen; Meng Xu; Hussein Abou-Hamdan; Mingliang Tang; Laurent Désaubry; Zhiyin Song
Journal:  Autophagy       Date:  2019-06-16       Impact factor: 16.016

4.  Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor.

Authors:  Yongjie Wei; Wei-Chung Chiang; Rhea Sumpter; Prashant Mishra; Beth Levine
Journal:  Cell       Date:  2016-12-22       Impact factor: 41.582

Review 5.  A Unifying Hypothesis Linking Hepatic Adaptations for Ethanol Metabolism to the Proinflammatory and Profibrotic Events of Alcoholic Liver Disease.

Authors:  Zhi Zhong; John J Lemasters
Journal:  Alcohol Clin Exp Res       Date:  2018-09-17       Impact factor: 3.455

6.  Role of mitochondrial depolarization and disrupted mitochondrial homeostasis in non-alcoholic steatohepatitis and fibrosis in mice.

Authors:  Yasodha Krishnasamy; Monika Gooz; Li Li; John J Lemasters; Zhi Zhong
Journal:  Int J Physiol Pathophysiol Pharmacol       Date:  2019-10-15

7.  Time-Lapse Video Microscopy for Assessment of EYFP-Parkin Aggregation as a Marker for Cellular Mitophagy.

Authors:  Gabriele Di Sante; Mathew C Casimiro; Timothy G Pestell; Richard G Pestell
Journal:  J Vis Exp       Date:  2016-05-04       Impact factor: 1.355

Review 8.  Differential regulation of autophagy and mitophagy in pulmonary diseases.

Authors:  Saurabh Aggarwal; Praveen Mannam; Jianhua Zhang
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2016-07-08       Impact factor: 5.464

9.  Cytoplasmic inheritance of mitochondria and chloroplasts in the anisogamous brown alga Mutimo cylindricus (Phaeophyceae).

Authors:  Yuan Shen; Toyoki Iwao; Taizo Motomura; Chikako Nagasato
Journal:  Protoplasma       Date:  2020-08-29       Impact factor: 3.356

10.  Autophagy and mitophagy in hepatocarcinogenesis.

Authors:  Kai Liu; Jiyoung Lee; Jing-Hsiung James Ou
Journal:  Mol Cell Oncol       Date:  2018-01-23
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