Literature DB >> 24807457

Prerequisites to implementing a pharmacogenomics program in a large health-care system.

K D Levy1, B S Decker2, J S Carpenter3, D A Flockhart4, P R Dexter5, Z Desta1, T C Skaar1.   

Abstract

Pharmacogenomics (PGx) technology is advancing rapidly; however, clinical adoption is lagging. The Indiana Institute of Personalized Medicine (IIPM) places a strong focus on translating PGx research into clinical practice. We describe what have been found to be the key requirements that must be delivered in order to ensure a successful and enduring PGx implementation within a large health-care system.

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Year:  2014        PMID： 24807457      PMCID： PMC4441093          DOI： 10.1038/clpt.2014.101

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


  3 in total

1.  Pharmacogenetics in clinical practice: how far have we come and where are we going?

Authors:  Julie A Johnson
Journal:  Pharmacogenomics       Date:  2013-05       Impact factor: 2.533

2.  A framework to evaluate the economic impact of pharmacogenomics.

Authors:  Sarah C Stallings; Dan Huse; Stan N Finkelstein; William H Crown; Whitney P Witt; Jon Maguire; Arthur J Hiller; Anthony J Sinskey; Geoffrey S Ginsburg
Journal:  Pharmacogenomics       Date:  2006-09       Impact factor: 2.533

3.  Implications of the Human Genome Project for medical science.

Authors:  F S Collins; V A McKusick
Journal:  JAMA       Date:  2001-02-07       Impact factor: 56.272
  3 in total
  15 in total

1.  Potentially actionable pharmacogenetic variants and symptom control medications in oncology.

Authors:  Jai N Patel; Danielle Boselli; Elizabeth J Jandrisevits; Issam S Hamadeh; Ahmed Salem; Patrick Meadors; Declan Walsh
Journal:  Support Care Cancer       Date:  2021-03-24       Impact factor: 3.603

Review 2.  Pharmacogenomics in the clinic.

Authors:  Mary V Relling; William E Evans
Journal:  Nature       Date:  2015-10-15       Impact factor: 49.962

3.  Iterative Development and Evaluation of a Pharmacogenomic-Guided Clinical Decision Support System for Warfarin Dosing.

Authors:  Brittany L Melton; Alan J Zillich; Jason Saleem; Alissa L Russ; James E Tisdale; Brian R Overholser
Journal:  Appl Clin Inform       Date:  2016-11-23       Impact factor: 2.342

Review 4.  Implementation of a pharmacogenomics consult service to support the INGENIOUS trial.

Authors:  M T Eadon; Z Desta; K D Levy; B S Decker; R C Pierson; V M Pratt; J T Callaghan; M B Rosenman; J S Carpenter; A M Holmes; C A McDonald; E A Benson; A S Patil; R Vuppalanchi; B T Gufford; N Dave; J D Robarge; M A Hyder; D M Haas; R P Kreutz; P R Dexter; T C Skaar; D A Flockhart
Journal:  Clin Pharmacol Ther       Date:  2016-03-31       Impact factor: 6.875

5.  Drug-gene and drug-drug interactions associated with tramadol and codeine therapy in the INGENIOUS trial.

Authors:  Cathy R Fulton; Yong Zang; Zeruesenay Desta; Marc B Rosenman; Ann M Holmes; Brian S Decker; Yifei Zhang; John T Callaghan; Victoria M Pratt; Kenneth D Levy; Brandon T Gufford; Paul R Dexter; Todd C Skaar; Michael T Eadon
Journal:  Pharmacogenomics       Date:  2019-02-20       Impact factor: 2.533

6.  CYP2D6 drug-gene and drug-drug-gene interactions among patients prescribed pharmacogenetically actionable opioids.

Authors:  Mitchell R Knisely; Janet S Carpenter; Claire Burke Draucker; Todd Skaar; Marion E Broome; Ann M Holmes; Diane Von Ah
Journal:  Appl Nurs Res       Date:  2017-10-07       Impact factor: 2.257

7.  Pharmacogenetics in Cardiovascular Medicine.

Authors:  Sony Tuteja; Nita Limdi
Journal:  Curr Genet Med Rep       Date:  2016-06-16

Review 8.  Personalized pediatric anesthesia and pain management: problem-based review.

Authors:  Senthil Packiasabapathy; Valluvan Rangasamy; Nicole Horn; Michele Hendrickson; Janelle Renschler; Senthilkumar Sadhasivam
Journal:  Pharmacogenomics       Date:  2020-01       Impact factor: 2.533

9.  Genetic Variants Contributing to Colistin Cytotoxicity: Identification of TGIF1 and HOXD10 Using a Population Genomics Approach.

Authors:  Michael T Eadon; Ronald J Hause; Amy L Stark; Ying-Hua Cheng; Heather E Wheeler; Kimberly S Burgess; Eric A Benson; Patrick N Cunningham; Robert L Bacallao; Pierre C Dagher; Todd C Skaar; M Eileen Dolan
Journal:  Int J Mol Sci       Date:  2017-03-18       Impact factor: 5.923

10.  Implementing Pharmacogenomics at Your Institution: Establishment and Overcoming Implementation Challenges.

Authors:  M J Arwood; S Chumnumwat; L H Cavallari; E A Nutescu; J D Duarte
Journal:  Clin Transl Sci       Date:  2016-06-14       Impact factor: 4.689
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