| Literature DB >> 2477704 |
M Sopta1, Z F Burton, J Greenblatt.
Abstract
RAP30/74 is a heteromeric general transcription initiation factor which binds to RNA polymerase II. Here we report that preparations of RAP30/74 contain an ATP-dependent DNA helicase whose probable function is to melt the DNA at transcriptional start sites. The sequence of the RAP30 subunit of RAP30/74 indicates that RAP30 may be distantly related to bacterial sigma factors.Entities:
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Year: 1989 PMID: 2477704 DOI: 10.1038/341410a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962