Literature DB >> 2477704

Structure and associated DNA-helicase activity of a general transcription initiation factor that binds to RNA polymerase II.

M Sopta1, Z F Burton, J Greenblatt.   

Abstract

RAP30/74 is a heteromeric general transcription initiation factor which binds to RNA polymerase II. Here we report that preparations of RAP30/74 contain an ATP-dependent DNA helicase whose probable function is to melt the DNA at transcriptional start sites. The sequence of the RAP30 subunit of RAP30/74 indicates that RAP30 may be distantly related to bacterial sigma factors.

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Year:  1989        PMID: 2477704     DOI: 10.1038/341410a0

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  65 in total

1.  Identification of a DNA supercoiling activity in Saccharomyces cerevisiae.

Authors:  H S Koo; K Lau; H Y Wu; L F Liu
Journal:  Nucleic Acids Res       Date:  1992-10-11       Impact factor: 16.971

Review 2.  Structure and mechanism of the RNA polymerase II transcription machinery.

Authors:  Steven Hahn
Journal:  Nat Struct Mol Biol       Date:  2004-05       Impact factor: 15.369

3.  Imperfect conservation of a sigma factor-like subregion in Xenopus general transcription factor RAP30.

Authors:  D W Gong; S Hashimoto; K Wada; R G Roeder; Y Nakatani; M Horikoshi
Journal:  Nucleic Acids Res       Date:  1992-12-11       Impact factor: 16.971

4.  An essential Saccharomyces cerevisiae gene homologous to SNF2 encodes a helicase-related protein in a new family.

Authors:  B C Laurent; X Yang; M Carlson
Journal:  Mol Cell Biol       Date:  1992-04       Impact factor: 4.272

5.  Mechanism of promoter selection by RNA polymerase II: mammalian transcription factors alpha and beta gamma promote entry of polymerase into the preinitiation complex.

Authors:  R C Conaway; K P Garrett; J P Hanley; J W Conaway
Journal:  Proc Natl Acad Sci U S A       Date:  1991-07-15       Impact factor: 11.205

6.  Isolation and characterization of a cDNA encoding Drosophila transcription factor TFIIB.

Authors:  S Yamashita; K Wada; M Horikoshi; D W Gong; T Kokubo; K Hisatake; N Yokotani; S Malik; R G Roeder; Y Nakatani
Journal:  Proc Natl Acad Sci U S A       Date:  1992-04-01       Impact factor: 11.205

7.  Isolation and nucleotide sequence of a rat cDNA homologous to human RAP30.

Authors:  Y Kobayashi; S Kitajima; Y Yasukochi
Journal:  Nucleic Acids Res       Date:  1992-04-25       Impact factor: 16.971

8.  Amino acid substitutions in yeast TFIIF confer upstream shifts in transcription initiation and altered interaction with RNA polymerase II.

Authors:  Mohamed A Ghazy; Seth A Brodie; Michelle L Ammerman; Lynn M Ziegler; Alfred S Ponticelli
Journal:  Mol Cell Biol       Date:  2004-12       Impact factor: 4.272

9.  Molecular cloning of cDNA encoding the small subunit of Drosophila transcription initiation factor TFIIF.

Authors:  D W Gong; M A Mortin; M Horikoshi; Y Nakatani
Journal:  Nucleic Acids Res       Date:  1995-06-11       Impact factor: 16.971

10.  Dissection of transcription factor TFIIF functional domains required for initiation and elongation.

Authors:  S Tan; R C Conaway; J W Conaway
Journal:  Proc Natl Acad Sci U S A       Date:  1995-06-20       Impact factor: 11.205

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