Literature DB >> 24746113

Molecular mechanism and therapeutic modulation of high mobility group box 1 release and action: an updated review.

Ben Lu1, Ce Wang, Mao Wang, Wei Li, Fangping Chen, Kevin J Tracey, Haichao Wang.   

Abstract

High mobility group box 1 (HMGB1) is an evolutionarily conserved protein, and is constitutively expressed in virtually all types of cells. Infection and injury converge on common inflammatory responses that are mediated by HMGB1 secreted from immunologically activated immune cells or passively released from pathologically damaged cells. Herein we review the emerging molecular mechanisms underlying the regulation of pathogen-associated molecular patterns (PAMPs)-induced HMGB1 secretion, and summarize many HMGB1-targeting therapeutic strategies for the treatment of infection- and injury-elicited inflammatory diseases. It may well be possible to develop strategies that specifically attenuate damage-associated molecular patterns (DAMPs)-mediated inflammatory responses without compromising the PAMPs-mediated innate immunity for the clinical management of infection- and injury-elicited inflammatory diseases.

Entities:  

Keywords:  damage-associated molecular patterns; herbal components; high mobility group box 1; infection; injury; pathogen-associated molecular patterns; signaling

Mesh：

Substances：

Year:  2014        PMID： 24746113      PMCID： PMC4056343          DOI： 10.1586/1744666X.2014.909730

Source DB:  PubMed          Journal:  Expert Rev Clin Immunol        ISSN： 1744-666X            Impact factor:   4.473


  170 in total

1.  Protective targeting of high mobility group box chromosomal protein 1 in a spontaneous arthritis model.

Authors:  Therese Ostberg; Kohki Kawane; Shigekazu Nagata; Huan Yang; Sangeeta Chavan; Lena Klevenvall; Marco E Bianchi; Helena Erlandsson Harris; Ulf Andersson; Karin Palmblad
Journal:  Arthritis Rheum       Date:  2010-10

2.  Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion.

Authors:  Tiziana Bonaldi; Fabio Talamo; Paola Scaffidi; Denise Ferrera; Annalisa Porto; Angela Bachi; Anna Rubartelli; Alessandra Agresti; Marco E Bianchi
Journal:  EMBO J       Date:  2003-10-15       Impact factor: 11.598

3.  Synergistic effects of recombinant human soluble thrombomodulin and fluid-volume resuscitation in a rat lethal crush injury model.

Authors:  Tomoyoshi Mohri; Hiroshi Tanaka; Goro Tajima; Kentaro Kajino; Hideaki Sonoi; Hideo Hosotsubo; Hiroshi Ogura; Yasuyuki Kuwagata; Takeshi Shimazu; Hisashi Sugimoto
Journal:  Shock       Date:  2006-12       Impact factor: 3.454

4.  High mobility group box1 (HMGB1) in relation to cutaneous inflammation in systemic lupus erythematosus (SLE).

Authors:  D A Abdulahad; J Westra; E Reefman; E Zuidersma; J Bijzet; P C Limburg; C G M Kallenberg; M Bijl
Journal:  Lupus       Date:  2013-04-02       Impact factor: 2.911

5.  HMGB1: a novel Beclin 1-binding protein active in autophagy.

Authors:  Rui Kang; Kristen M Livesey; Herbert J Zeh; Michael T Loze; Daolin Tang
Journal:  Autophagy       Date:  2010-11-16       Impact factor: 16.016

6.  IFN-gamma induces high mobility group box 1 protein release partly through a TNF-dependent mechanism.

Authors:  Beatriz Rendon-Mitchell; Mahendar Ochani; Jianhua Li; Jialian Han; Hong Wang; Huan Yang; Seenu Susarla; Christopher Czura; Robert A Mitchell; Guoqian Chen; Andrew E Sama; Kevin J Tracey; Haichao Wang
Journal:  J Immunol       Date:  2003-04-01       Impact factor: 5.422

7.  Tunable signal processing through modular control of transcription factor translocation.

Authors:  Nan Hao; Bogdan A Budnik; Jeremy Gunawardena; Erin K O'Shea
Journal:  Science       Date:  2013-01-25       Impact factor: 47.728

8.  Bacterial endotoxin induces the release of high mobility group box 1 via the IFN-beta signaling pathway.

Authors:  Ju-Hyun Kim; Seon-Ju Kim; Im-Soon Lee; Myung-Shik Lee; Satoshi Uematsu; Shizuo Akira; Kwon Ik Oh
Journal:  J Immunol       Date:  2009-02-15       Impact factor: 5.422

9.  A systematic nomenclature for the redox states of high mobility group box (HMGB) proteins.

Authors:  Daniel J Antoine; Helena Erlandsson Harris; Ulf Andersson; Kevin J Tracey; Marco E Bianchi
Journal:  Mol Med       Date:  2014-03-24       Impact factor: 6.354

10.  Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation.

Authors:  Young Sik Cho; Sreerupa Challa; David Moquin; Ryan Genga; Tathagat Dutta Ray; Melissa Guildford; Francis Ka-Ming Chan
Journal:  Cell       Date:  2009-06-12       Impact factor: 41.582
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  60 in total

1.  Association Between HMGB1 and Thrombogenesis in a Hyperlipaemia-induced Microminipig Model of Atherosclerosis.

Authors:  Satoru Kake; Hiroaki Kawaguchi; Tomoka Nagasato; Tomonobu Yamada; Takashi Ito; Ikuro Maruyama; Naoki Miura; Akihide Tanimoto
Journal:  In Vivo       Date:  2020 Jul-Aug       Impact factor: 2.155

2.  microRNA-218 promotes gemcitabine sensitivity in human pancreatic cancer cells by regulating HMGB1 expression.

Authors:  Zhe Liu; Ruixia Du; Jin Long; Kejian Guo; Chunlin Ge; Shulong Bi; Yuanhong Xu
Journal:  Chin J Cancer Res       Date:  2015-06       Impact factor: 5.087

3.  Blocking cold-inducible RNA-binding protein protects liver from ischemia-reperfusion injury.

Authors:  Andrew Godwin; Weng-Lang Yang; Archna Sharma; Adam Khader; Zhimin Wang; Fangming Zhang; Jeffrey Nicastro; Gene F Coppa; Ping Wang
Journal:  Shock       Date:  2015-01       Impact factor: 3.454

4.  Pulmonary Epithelial TLR4 Activation Leads to Lung Injury in Neonatal Necrotizing Enterocolitis.

Authors:  Hongpeng Jia; Chhinder P Sodhi; Yukihiro Yamaguchi; Peng Lu; Laura Y Martin; Misty Good; Qinjie Zhou; Jungeun Sung; William B Fulton; Diego F Nino; Thomas Prindle; John A Ozolek; David J Hackam
Journal:  J Immunol       Date:  2016-06-15       Impact factor: 5.422

Review 5.  The Role of HMGB1, a Nuclear Damage-Associated Molecular Pattern Molecule, in the Pathogenesis of Lung Diseases.

Authors:  Mao Wang; Alex Gauthier; LeeAnne Daley; Katelyn Dial; Jiaqi Wu; Joanna Woo; Mosi Lin; Charles Ashby; Lin L Mantell
Journal:  Antioxid Redox Signal       Date:  2019-07-11       Impact factor: 8.401

Review 6.  Role of Microglial Activation in the Pathophysiology of Bacterial Meningitis.

Authors:  Tatiana Barichello; Jaqueline S Generoso; Lutiana R Simões; Jessica A Goularte; Fabricia Petronilho; Priyanka Saigal; Marwa Badawy; João Quevedo
Journal:  Mol Neurobiol       Date:  2015-03-07       Impact factor: 5.590

7.  Ischemic preconditioning attenuates acute lung injury after partial liver transplantation.

Authors:  Qinlong Liu; Hasibur Rehman; Yasodha Krishnasamy; John J Lemasters; Zhi Zhong
Journal:  Int J Physiol Pathophysiol Pharmacol       Date:  2018-04-20

8.  HMGB1 promotes ductular reaction and tumorigenesis in autophagy-deficient livers.

Authors:  Bilon Khambu; Nazmul Huda; Xiaoyun Chen; Daniel J Antoine; Yong Li; Guoli Dai; Ulrike A Köhler; Wei-Xing Zong; Satoshi Waguri; Sabine Werner; Tim D Oury; Zheng Dong; Xiao-Ming Yin
Journal:  J Clin Invest       Date:  2018-05-07       Impact factor: 14.808

9.  Propofol Protects Rats and Human Alveolar Epithelial Cells Against Lipopolysaccharide-Induced Acute Lung Injury via Inhibiting HMGB1 Expression.

Authors:  Xiaoyan Wang; Chengxiao Liu; Gongming Wang
Journal:  Inflammation       Date:  2016-06       Impact factor: 4.092

10.  MicroRNA-142-3p Inhibits Chondrocyte Apoptosis and Inflammation in Osteoarthritis by Targeting HMGB1.

Authors:  Xiuqin Wang; Yanqing Guo; Chunyan Wang; Hong Yu; Xiuxiang Yu; Hongbo Yu
Journal:  Inflammation       Date:  2016-10       Impact factor: 4.092
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