Literature DB >> 24732145

'Obesity paradox' misunderstands the biology of optimal weight throughout the life cycle.

J B Dixon1, G J Egger2, E A Finkelstein3, J G Kral4, G W Lambert1.   

Abstract

The 'obesity paradox' refers to observations that run counter to the thesis that normal weight (BMI 18.5-24.9 g/m(2)) provides the lowest mortality and higher weight is associated with greater mortality. We argue that the weight of lowest mortality is influenced by aging and chronic disease, with mortality advantage extending into the overweight and even class I obese ranges under some circumstances. A focus on quality nutrition, physical activity, fitness, and maintaining function in these weight ranges may be preferable to a focus on intentional weight loss, which has uncertain effects. The 'obesity paradox' is no 'paradox' if one defines and interprets 'ideal' weight appropriately.

Entities:  

Mesh:

Year:  2014        PMID: 24732145     DOI: 10.1038/ijo.2014.59

Source DB:  PubMed          Journal:  Int J Obes (Lond)        ISSN: 0307-0565            Impact factor:   5.095


  27 in total

1.  Metabolically healthy obese women and functional capacity.

Authors:  Danielle R Bouchard; Marie-France Langlois; Martin Brochu; Isabelle J Dionne; Jean-Patrice Baillargeon
Journal:  Metab Syndr Relat Disord       Date:  2011-03-01       Impact factor: 1.894

2.  The association between obesity and mortality in the elderly differs by serum concentrations of persistent organic pollutants: a possible explanation for the obesity paradox.

Authors:  N S Hong; K S Kim; I K Lee; P M Lind; L Lind; D R Jacobs; D H Lee
Journal:  Int J Obes (Lond)       Date:  2011-09-27       Impact factor: 5.095

3.  Obesity and mortality risk: new findings from body mass index trajectories.

Authors:  Hui Zheng; Dmitry Tumin; Zhenchao Qian
Journal:  Am J Epidemiol       Date:  2013-09-07       Impact factor: 4.897

4.  Survival among high-risk patients after bariatric surgery.

Authors:  Matthew L Maciejewski; Edward H Livingston; Valerie A Smith; Andrew L Kavee; Leila C Kahwati; William G Henderson; David E Arterburn
Journal:  JAMA       Date:  2011-06-12       Impact factor: 56.272

5.  Body mass index and the prevalence of hypertension and dyslipidemia.

Authors:  C D Brown; M Higgins; K A Donato; F C Rohde; R Garrison; E Obarzanek; N D Ernst; M Horan
Journal:  Obes Res       Date:  2000-12

6.  Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes.

Authors:  Rena R Wing; Paula Bolin; Frederick L Brancati; George A Bray; Jeanne M Clark; Mace Coday; Richard S Crow; Jeffrey M Curtis; Caitlin M Egan; Mark A Espeland; Mary Evans; John P Foreyt; Siran Ghazarian; Edward W Gregg; Barbara Harrison; Helen P Hazuda; James O Hill; Edward S Horton; Van S Hubbard; John M Jakicic; Robert W Jeffery; Karen C Johnson; Steven E Kahn; Abbas E Kitabchi; William C Knowler; Cora E Lewis; Barbara J Maschak-Carey; Maria G Montez; Anne Murillo; David M Nathan; Jennifer Patricio; Anne Peters; Xavier Pi-Sunyer; Henry Pownall; David Reboussin; Judith G Regensteiner; Amy D Rickman; Donna H Ryan; Monika Safford; Thomas A Wadden; Lynne E Wagenknecht; Delia S West; David F Williamson; Susan Z Yanovski
Journal:  N Engl J Med       Date:  2013-06-24       Impact factor: 91.245

7.  The obesity paradox and weight loss.

Authors:  Jonathan Myers; Kusum Lata; Shilpy Chowdhury; Paul McAuley; Nikhil Jain; Victor Froelicher
Journal:  Am J Med       Date:  2011-07-26       Impact factor: 4.965

8.  Inverse association between adiposity and telomere length: The Fels Longitudinal Study.

Authors:  Miryoung Lee; Hilarie Martin; Matthew A Firpo; Ellen W Demerath
Journal:  Am J Hum Biol       Date:  2011 Jan-Feb       Impact factor: 1.937

9.  Obesity, fat distribution, and weight gain as risk factors for clinical diabetes in men.

Authors:  J M Chan; E B Rimm; G A Colditz; M J Stampfer; W C Willett
Journal:  Diabetes Care       Date:  1994-09       Impact factor: 19.112

Review 10.  Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis.

Authors:  Katherine M Flegal; Brian K Kit; Heather Orpana; Barry I Graubard
Journal:  JAMA       Date:  2013-01-02       Impact factor: 56.272

View more
  23 in total

1.  MicroRNA-155 Deficiency Leads to Decreased Atherosclerosis, Increased White Adipose Tissue Obesity, and Non-alcoholic Fatty Liver Disease: A NOVEL MOUSE MODEL OF OBESITY PARADOX.

Authors:  Anthony Virtue; Candice Johnson; Jahaira Lopez-Pastraña; Ying Shao; Hangfei Fu; Xinyuan Li; Ya-Feng Li; Ying Yin; Jietang Mai; Victor Rizzo; Michael Tordoff; Zsolt Bagi; Huimin Shan; Xiaohua Jiang; Hong Wang; Xiao-Feng Yang
Journal:  J Biol Chem       Date:  2016-11-17       Impact factor: 5.157

Review 2.  The Role of Adipose Tissue and Adipokines in Sepsis: Inflammatory and Metabolic Considerations, and the Obesity Paradox.

Authors:  Irene Karampela; Gerasimos Socrates Christodoulatos; Maria Dalamaga
Journal:  Curr Obes Rep       Date:  2019-12

3.  Effect of BMI and fat mass on HIV disease progression in HIV-infected, antiretroviral treatment-naïve adults in Botswana.

Authors:  S S Martinez; A Campa; H Bussmann; S Moyo; J Makhema; F G Huffman; O D Williams; M Essex; R Marlink; M K Baum
Journal:  Br J Nutr       Date:  2016-04-18       Impact factor: 3.718

4.  Obesity and extent of emphysema depicted at CT.

Authors:  S Gu; R Li; J K Leader; B Zheng; J Bon; D Gur; F Sciurba; C Jin; J Pu
Journal:  Clin Radiol       Date:  2015-02-19       Impact factor: 2.350

5.  Impact of BMI on Long-Term Outcomes in Patients with ST-Segment Elevation Myocardial Infarction after Primary Percutaneous Coronary Intervention.

Authors:  Jinwen Wang; Changhua Wang; Zhechun Zeng; Huijuan Zuo
Journal:  Int J Clin Pract       Date:  2022-01-31       Impact factor: 3.149

6.  Overweight and obese midlife women in Israel: cultural differences in perceived weight status.

Authors:  Roni Elran-Barak; Tzvia Blumstein; Valentina Boyko; Dana Hadar; Adel Farhi; Liat Lerner-Geva; Yael Benyamini
Journal:  Int J Public Health       Date:  2015-10-26       Impact factor: 3.380

7.  Inflammation Modifies the Paradoxical Association between Body Mass Index and Mortality in Hemodialysis Patients.

Authors:  Peter Stenvinkel; Iain A Gillespie; Jamie Tunks; Janet Addison; Florian Kronenberg; Tilman B Drueke; Daniele Marcelli; Guntram Schernthaner; Kai-Uwe Eckardt; Jürgen Floege; Marc Froissart; Stefan D Anker
Journal:  J Am Soc Nephrol       Date:  2015-11-13       Impact factor: 10.121

8.  Obesity Paradox should not interfere with public health efforts.

Authors:  J Stevens; P T Bradshaw; K P Truesdale; M D Jensen
Journal:  Int J Obes (Lond)       Date:  2014-04-15       Impact factor: 5.095

9.  Age-Related Biomarkers in LLFS Families With Exceptional Cognitive Abilities.

Authors:  Sandra Barral; Jatinder Singh; Erin Fagan; Stephanie Cosentino; Stacy L Andersen-Toomey; Mary K Wojczynski; Mary Feitosa; Candace M Kammerer; Nicole Schupf
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2017-11-09       Impact factor: 6.053

10.  Collider Bias Is Only a Partial Explanation for the Obesity Paradox.

Authors:  Matthew Sperrin; Jane Candlish; Ellena Badrick; Andrew Renehan; Iain Buchan
Journal:  Epidemiology       Date:  2016-07       Impact factor: 4.822

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.