Lucia Ramsey1, Robert John Winder, Joseph G McVeigh. 1. Centre for Health and Rehabilitation Technologies (CHaRT), School of Health Sciences, University of Ulster, , Shore Road , BT370QB UK, United Kingdom. l.ramsey@ulster.ac.uk.
Abstract
OBJECTIVE: To evaluate the effectiveness of working wrist splints in people with rheumatoid arthritis. DATA SOURCES AND STUDY SELECTION: This review adhered to the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. Ten databases were searched from inception until September 2012 for quantitative and qualitative studies on the effectiveness of working wrist splints in rheumatoid arthritis. DATA EXTRACTION: Data was extracted on participants, interventions, outcome measures and results. Experimental studies were evaluated using the van Tulder scale and the Cochrane Risk of Bias tool. Data was extracted by a single reviewer and all studies were reviewed by two blind reviewers. DATA SYNTHESIS: Twenty-three studies were included in the review (n = 1,492), 13 experimental studies including 9 randomized controlled trials (RCTs) and 2 qualitative studies. Data was summarized using best evidence synthesis and a meta-ethnographical approach guided qualitative evidence synthesis. There is strong quantitative evidence (including 9 RCTs), supported by conclusions from qualitative literature, that working wrist splints reduce pain (d = 0.7-0.8), moderate evidence that grip strength is improved (d = 0.3-0.4) and dexterity impaired and insufficient evidence of their effect on function. CONCLUSIONS: Working wrist splints reduce pain and improve grip in rheumatoid arthritis. The effect of splints on function is not yet clear.
OBJECTIVE: To evaluate the effectiveness of working wrist splints in people with rheumatoid arthritis. DATA SOURCES AND STUDY SELECTION: This review adhered to the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. Ten databases were searched from inception until September 2012 for quantitative and qualitative studies on the effectiveness of working wrist splints in rheumatoid arthritis. DATA EXTRACTION: Data was extracted on participants, interventions, outcome measures and results. Experimental studies were evaluated using the van Tulder scale and the Cochrane Risk of Bias tool. Data was extracted by a single reviewer and all studies were reviewed by two blind reviewers. DATA SYNTHESIS: Twenty-three studies were included in the review (n = 1,492), 13 experimental studies including 9 randomized controlled trials (RCTs) and 2 qualitative studies. Data was summarized using best evidence synthesis and a meta-ethnographical approach guided qualitative evidence synthesis. There is strong quantitative evidence (including 9 RCTs), supported by conclusions from qualitative literature, that working wrist splints reduce pain (d = 0.7-0.8), moderate evidence that grip strength is improved (d = 0.3-0.4) and dexterity impaired and insufficient evidence of their effect on function. CONCLUSIONS: Working wrist splints reduce pain and improve grip in rheumatoid arthritis. The effect of splints on function is not yet clear.
Authors: Fernando Blaya; Pilar San Pedro; Julia López Silva; Roberto D'Amato; Enrique Soriano Heras; Juan Antonio Juanes Journal: J Med Syst Date: 2018-02-05 Impact factor: 4.460
Authors: Shailesh Agarwal; Shawn J Loder; David Cholok; John Li; Guowu Bian; Srilakshmi Yalavarthi; Shuli Li; William F Carson; Charles Hwang; Simone Marini; Chase Pagani; Nicole Edwards; Matthew J Delano; Theodore J Standiford; Jason S Knight; Steven L Kunkel; Yuji Mishina; Peter A Ward; Benjamin Levi Journal: Front Immunol Date: 2019-10-24 Impact factor: 7.561