Literature DB >> 24697267

Evaluation of allelic strength of human TET2 mutations and cooperation between Tet2 knockdown and oncogenic Nras mutation.

Yuan-I Chang1, Alisa Damnernsawad, Laura K Allen, David Yang, Erik A Ranheim, Ken H Young, Jingfang Zhang, Guangyao Kong, Jinyong Wang, Yangang Liu, Hsu-Yuan Fu, Chii-Shen Yang, Junjie Guo, Hongjun Song, Jing Zhang.   

Abstract

Entities:  

Keywords:  5hmc; TET2; chronic myelomonocytic leukaemia; oncogenic RAS; whole exome sequencing

Mesh：

Substances：

Year:  2014        PMID： 24697267      PMCID： PMC4107140          DOI： 10.1111/bjh.12871

Source DB:  PubMed          Journal:  Br J Haematol        ISSN： 0007-1048            Impact factor:   6.998


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  10 in total

1.  Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity.

Authors:  Till Maurer; Lindsay S Garrenton; Angela Oh; Keith Pitts; Daniel J Anderson; Nicholas J Skelton; Benjamin P Fauber; Borlan Pan; Shiva Malek; David Stokoe; Mary J C Ludlam; Krista K Bowman; Jiansheng Wu; Anthony M Giannetti; Melissa A Starovasnik; Ira Mellman; Peter K Jackson; Joachim Rudolph; Weiru Wang; Guowei Fang
Journal:  Proc Natl Acad Sci U S A       Date:  2012-03-19       Impact factor: 11.205

2.  Incidence and prognostic value of TET2 alterations in de novo acute myeloid leukemia achieving complete remission.

Authors:  Olivier Nibourel; Olivier Kosmider; Meyling Cheok; Nicolas Boissel; Aline Renneville; Nathalie Philippe; Hervé Dombret; François Dreyfus; Bruno Quesnel; Sandrine Geffroy; Samuel Quentin; Catherine Roche-Lestienne; Jean-Michel Cayuela; Christophe Roumier; Pierre Fenaux; William Vainchenker; Olivier A Bernard; Jean Soulier; Michaëla Fontenay; Claude Preudhomme
Journal:  Blood       Date:  2010-05-20       Impact factor: 22.113

3.  The Interlaboratory RObustness of Next-generation sequencing (IRON) study: a deep sequencing investigation of TET2, CBL and KRAS mutations by an international consortium involving 10 laboratories.

Authors:  A Kohlmann; H-U Klein; S Weissmann; S Bresolin; T Chaplin; H Cuppens; E Haschke-Becher; B Garicochea; V Grossmann; B Hanczaruk; K Hebestreit; C Gabriel; I Iacobucci; J H Jansen; G te Kronnie; L van de Locht; G Martinelli; K McGowan; M R Schweiger; B Timmermann; P Vandenberghe; B D Young; M Dugas; T Haferlach
Journal:  Leukemia       Date:  2011-06-17       Impact factor: 11.528

Review 4.  The role of mutations in epigenetic regulators in myeloid malignancies.

Authors:  Alan H Shih; Omar Abdel-Wahab; Jay P Patel; Ross L Levine
Journal:  Nat Rev Cancer       Date:  2012-08-17       Impact factor: 60.716

5.  Cytoplasmatic compartmentalization by Bcr-Abl promotes TET2 loss-of-function in chronic myeloid leukemia.

Authors:  Manuela Mancini; Nevena Veljkovic; Elisa Leo; Michela Aluigi; Enrica Borsi; Chiara Galloni; Ilaria Iacobucci; Enza Barbieri; Maria Alessandra Santucci
Journal:  J Cell Biochem       Date:  2012-08       Impact factor: 4.429

Review 6.  TET family proteins and their role in stem cell differentiation and transformation.

Authors:  Luisa Cimmino; Omar Abdel-Wahab; Ross L Levine; Iannis Aifantis
Journal:  Cell Stem Cell       Date:  2011-09-02       Impact factor: 24.633

7.  Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.

Authors:  Myunggon Ko; Yun Huang; Anna M Jankowska; Utz J Pape; Mamta Tahiliani; Hozefa S Bandukwala; Jungeun An; Edward D Lamperti; Kian Peng Koh; Rebecca Ganetzky; X Shirley Liu; L Aravind; Suneet Agarwal; Jaroslaw P Maciejewski; Anjana Rao
Journal:  Nature       Date:  2010-12-09       Impact factor: 49.962

8.  Notch pathway activation targets AML-initiating cell homeostasis and differentiation.

Authors:  Camille Lobry; Panagiotis Ntziachristos; Delphine Ndiaye-Lobry; Philmo Oh; Luisa Cimmino; Nan Zhu; Elisa Araldi; Wenhuo Hu; Jacquelyn Freund; Omar Abdel-Wahab; Sherif Ibrahim; Dimitris Skokos; Scott A Armstrong; Ross L Levine; Christopher Y Park; Iannis Aifantis
Journal:  J Exp Med       Date:  2013-01-28       Impact factor: 14.307

9.  Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo.

Authors:  Omar Abdel-Wahab; Jie Gao; Mazhar Adli; Anwesha Dey; Thomas Trimarchi; Young Rock Chung; Cem Kuscu; Todd Hricik; Delphine Ndiaye-Lobry; Lindsay M Lafave; Richard Koche; Alan H Shih; Olga A Guryanova; Eunhee Kim; Sheng Li; Suveg Pandey; Joseph Y Shin; Leon Telis; Jinfeng Liu; Parva K Bhatt; Sebastien Monette; Xinyang Zhao; Christopher E Mason; Christopher Y Park; Bradley E Bernstein; Iannis Aifantis; Ross L Levine
Journal:  J Exp Med       Date:  2013-11-11       Impact factor: 14.307

10.  Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders.

Authors:  Tomoya Muto; Goro Sashida; Motohiko Oshima; George R Wendt; Makiko Mochizuki-Kashio; Yasunobu Nagata; Masashi Sanada; Satoru Miyagi; Atsunori Saraya; Asuka Kamio; Genta Nagae; Chiaki Nakaseko; Koutaro Yokote; Kazuya Shimoda; Haruhiko Koseki; Yutaka Suzuki; Sumio Sugano; Hiroyuki Aburatani; Seishi Ogawa; Atsushi Iwama
Journal:  J Exp Med       Date:  2013-11-11       Impact factor: 14.307
  10 in total
  9 in total

1.  Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity.

Authors:  Hiroyoshi Kunimoto; Cem Meydan; Abbas Nazir; Justin Whitfield; Kaitlyn Shank; Franck Rapaport; Rebecca Maher; Elodie Pronier; Sara C Meyer; Francine E Garrett-Bakelman; Martin Tallman; Ari Melnick; Ross L Levine; Alan H Shih
Journal:  Cancer Cell       Date:  2017-12-21       Impact factor: 31.743

Review 2.  DNA methylation in hematopoietic development and disease.

Authors:  Aniket V Gore; Brant M Weinstein
Journal:  Exp Hematol       Date:  2016-05-10       Impact factor: 3.084

3.  Loss of Dnmt3a and endogenous Kras(G12D/+) cooperate to regulate hematopoietic stem and progenitor cell functions in leukemogenesis.

Authors:  Y-I Chang; X You; G Kong; E A Ranheim; J Wang; J Du; Y Liu; Y Zhou; M-J Ryu; J Zhang
Journal:  Leukemia       Date:  2015-03-24       Impact factor: 11.528

Review 4.  TET proteins and 5-methylcytosine oxidation in hematological cancers.

Authors:  Myunggon Ko; Jungeun An; William A Pastor; Sergei B Koralov; Klaus Rajewsky; Anjana Rao
Journal:  Immunol Rev       Date:  2015-01       Impact factor: 12.988

Review 5.  DNA methylation and hydroxymethylation in hematologic differentiation and transformation.

Authors:  Myunggon Ko; Jungeun An; Anjana Rao
Journal:  Curr Opin Cell Biol       Date:  2015-11-18       Impact factor: 8.382

Review 6.  Interplay between Metabolism and Epigenetics: A Nuclear Adaptation to Environmental Changes.

Authors:  Jean-Pierre Etchegaray; Raul Mostoslavsky
Journal:  Mol Cell       Date:  2016-06-02       Impact factor: 17.970

7.  Oncogenic N-Ras and Tet2 haploinsufficiency collaborate to dysregulate hematopoietic stem and progenitor cells.

Authors:  Xi Jin; Tingting Qin; Meiling Zhao; Nathanael Bailey; Lu Liu; Kevin Yang; Victor Ng; Tomoyasu Higashimoto; Rosemary Coolon; Gina Ney; Maria E Figueroa; Qing Li
Journal:  Blood Adv       Date:  2018-06-12

Review 8.  Functions of TET Proteins in Hematopoietic Transformation.

Authors:  Jae-A Han; Jungeun An; Myunggon Ko
Journal:  Mol Cells       Date:  2015-11-10       Impact factor: 5.034

9.  Downregulating Notch counteracts KrasG12D-induced ERK activation and oxidative phosphorylation in myeloproliferative neoplasm.

Authors:  Guangyao Kong; Xiaona You; Zhi Wen; Yuan-I Chang; Shuiming Qian; Erik A Ranheim; Christopher Letson; Xinmin Zhang; Yun Zhou; Yangang Liu; Adhithi Rajagopalan; Jingfang Zhang; Elliot Stieglitz; Mignon Loh; Inga Hofmann; David Yang; Xuehua Zhong; Eric Padron; Lan Zhou; Warren S Pear; Jing Zhang
Journal:  Leukemia       Date:  2018-09-11       Impact factor: 11.528
  9 in total

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