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Literature DB >> 27178734

DNA methylation in hematopoietic development and disease.

Abstract

DNA methylation is an important epigenetic modification that can have profound and widespread effects on gene expression and on cellular fate and function. Recent work has indicated that DNA methylation plays a critical role in hematopoietic development and hematopoietic disease. DNA methyltransferases and Ten-eleven translocation enzymes are required to add and remove methyl "marks" from DNA, respectively, and both sets of genes have been found necessary for proper formation and maintenance of hematopoietic stem cells and for differentiation of downstream hematopoietic lineages during development. DNA methylation and demethylation enzymes have also been implicated in hematopoietic disorders such as acute myeloid leukemia and myelodysplastic syndrome. Here, we review some of the recent literature regarding the role of DNA methylation in hematopoietic health and disease. Published by Elsevier Inc.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2016 PMID： 27178734 PMCID： PMC4992597 DOI： 10.1016/j.exphem.2016.04.013

Source DB: PubMed Journal: Exp Hematol ISSN： 0301-472X Impact factor: 3.084

74 in total

Review 1. The journey of developing hematopoietic stem cells.

Authors: Hanna K A Mikkola; Stuart H Orkin
Journal: Development Date: 2006-10 Impact factor: 6.868

Review 2. Structure and function of mammalian DNA methyltransferases.

Authors: Renata Zofia Jurkowska; Tomasz Piotr Jurkowski; Albert Jeltsch
Journal: Chembiochem Date: 2010-11-29 Impact factor: 3.164

3. Inducing definitive hematopoiesis in a dish.

Authors: Mervin C Yoder
Journal: Nat Biotechnol Date: 2014-06 Impact factor: 54.908

4. Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation.

Authors: Allison Mayle; Liubin Yang; Benjamin Rodriguez; Ting Zhou; Edmund Chang; Choladda V Curry; Grant A Challen; Wei Li; David Wheeler; Vivienne I Rebel; Margaret A Goodell
Journal: Blood Date: 2015-01-22 Impact factor: 22.113

5. DNMT3A mutations in acute myeloid leukemia.

Authors: Timothy J Ley; Li Ding; Matthew J Walter; Michael D McLellan; Tamara Lamprecht; David E Larson; Cyriac Kandoth; Jacqueline E Payton; Jack Baty; John Welch; Christopher C Harris; Cheryl F Lichti; R Reid Townsend; Robert S Fulton; David J Dooling; Daniel C Koboldt; Heather Schmidt; Qunyuan Zhang; John R Osborne; Ling Lin; Michelle O'Laughlin; Joshua F McMichael; Kim D Delehaunty; Sean D McGrath; Lucinda A Fulton; Vincent J Magrini; Tammi L Vickery; Jasreet Hundal; Lisa L Cook; Joshua J Conyers; Gary W Swift; Jerry P Reed; Patricia A Alldredge; Todd Wylie; Jason Walker; Joelle Kalicki; Mark A Watson; Sharon Heath; William D Shannon; Nobish Varghese; Rakesh Nagarajan; Peter Westervelt; Michael H Tomasson; Daniel C Link; Timothy A Graubert; John F DiPersio; Elaine R Mardis; Richard K Wilson
Journal: N Engl J Med Date: 2010-11-10 Impact factor: 91.245

6. The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus.

Authors: D P Barlow; R Stöger; B G Herrmann; K Saito; N Schweifer
Journal: Nature Date: 1991-01-03 Impact factor: 49.962

7. Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin.

Authors: Bernhard Lehnertz; Yoshihide Ueda; Alwin A H A Derijck; Ulrich Braunschweig; Laura Perez-Burgos; Stefan Kubicek; Taiping Chen; En Li; Thomas Jenuwein; Antoine H F M Peters
Journal: Curr Biol Date: 2003-07-15 Impact factor: 10.834

8. Restoration of Runx1 expression in the Tie2 cell compartment rescues definitive hematopoietic stem cells and extends life of Runx1 knockout animals until birth.

Authors: Anna Liakhovitskaia; Ruby Gribi; Evangelos Stamateris; Gaelle Villain; Thierry Jaffredo; Ron Wilkie; Derek Gilchrist; Jian Yang; Janice Ure; Alexander Medvinsky
Journal: Stem Cells Date: 2009-07 Impact factor: 6.277

9. DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells.

Authors: Jennifer J Trowbridge; Jonathan W Snow; Jonghwan Kim; Stuart H Orkin
Journal: Cell Stem Cell Date: 2009-10-02 Impact factor: 24.633

10. Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation.

Authors: Lothar Schermelleh; Andrea Haemmer; Fabio Spada; Nicole Rösing; Daniela Meilinger; Ulrich Rothbauer; M Cristina Cardoso; Heinrich Leonhardt
Journal: Nucleic Acids Res Date: 2007-06-18 Impact factor: 16.971

11 in total

Review 1. The zebrafish: A fintastic model for hematopoietic development and disease.

Authors: Aniket V Gore; Laura M Pillay; Marina Venero Galanternik; Brant M Weinstein
Journal: Wiley Interdiscip Rev Dev Biol Date: 2018-02-13 Impact factor: 5.814

2. Differential DNA Methylation of Networked Signaling, Transcriptional, Innate and Adaptive Immunity, and Osteoclastogenesis Genes and Pathways in Gout.

Authors: Zengmiao Wang; Ying Zhao; Amanda Phipps-Green; Ru Liu-Bryan; Arnoldas Ceponis; David L Boyle; Jun Wang; Tony R Merriman; Wei Wang; Robert Terkeltaub
Journal: Arthritis Rheumatol Date: 2020-03-23 Impact factor: 10.995

DNA methylation in hematopoietic development and disease.

Review 1. The journey of developing hematopoietic stem cells.

Review 2. Structure and function of mammalian DNA methyltransferases.

3. Inducing definitive hematopoiesis in a dish.

4. Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation.

5. DNMT3A mutations in acute myeloid leukemia.

6. The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus.

7. Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin.

8. Restoration of Runx1 expression in the Tie2 cell compartment rescues definitive hematopoietic stem cells and extends life of Runx1 knockout animals until birth.

9. DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells.

10. Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation.

Review 1. The zebrafish: A fintastic model for hematopoietic development and disease.

2. Differential DNA Methylation of Networked Signaling, Transcriptional, Innate and Adaptive Immunity, and Osteoclastogenesis Genes and Pathways in Gout.

Review 3. Haematopoiesis in Zebrafish (Danio Rerio).

Review 4. DNA methylation: a saga of genome maintenance in hematological perspective.

5. [Effects of EZH2 siRNA silence on proliferation, apoptosis, and histone methylation, acetylation in HL-60 cells].

6. Hematopoietic stem and progenitor cell proliferation and differentiation requires the trithorax protein Ash2l.

Review 7. Nanopore Sequencing in Blood Diseases: A Wide Range of Opportunities.

Review 8. The DNA methylation landscape of hematological malignancies: an update.

Review 9. Runx Transcription Factors in T Cells-What Is Beyond Thymic Development?

Review 10. The role of m6A modification in the biological functions and diseases.