Literature DB >> 24688000

Common genetic variations in the vitamin D pathway in relation to blood pressure.

Lu Wang1, Audrey Chu2, Julie E Buring, Paul M Ridker3, Daniel I Chasman2, Howard D Sesso.   

Abstract

BACKGROUND: Vitamin D is involved in blood pressure (BP) regulation. Genetic variations may influence the effect of vitamin D on BP, but data from epidemiologic studies remain inconsistent.
METHODS: We conducted a comprehensive genetic association study in the Women's Genome Health Study (WGHS) with genome-wide genotype data among 23,294 women of European ancestry and in the International Consortium of Blood Pressure (ICBP) with genome-wide meta-analysis results from 69,395 men and women of European ancestry.
RESULTS: First, we found none of 5 selected vitamin D-related candidate single nucleotide polymorphisms (SNPs) was associated with systolic BP (SBP) or diastolic BP (DBP). Second, in 61 candidate SNPs involved in vitamin D metabolism and signaling, rs1507023 (in RBFOX1) and rs2296241 (in CYP24A1) showed significant associations with SBP, DBP, mean arterial pressure, or pulse pressure in the WGHS before, but not after, multiple testing corrections. Nominally significant associations in the ICBP were also not significant after corrections. Third, among 24 candidate genes across vitamin D pathway, associations with BP traits that meet gene-wide significance level were found for NCOA3 (rs2235734), RXRA (rs875444), DHCR7 (rs1790370), VDR (rs2544037), and NCOR2 (rs1243733, rs1147289) in the WGHS and NCOR1, TP53BP1, and TYRP1 in the ICBP. However, none of these associations reached significance threshold in both studies.
CONCLUSIONS: Our study did not replicate previously observed associations of vitamin D-related SNPs with BP. There was suggestive evidence for associations in other vitamin D pathway genes; however, these associations either did not reach the significance threshold or were not replicated. © American Journal of Hypertension, Ltd 2014. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Entities:  

Keywords:  blood pressure; epidemiology; genetics; hypertension; pathway; vitamin D; white population.

Mesh：

Substances：

Year:  2014        PMID： 24688000      PMCID： PMC4200063          DOI： 10.1093/ajh/hpu049

Source DB:  PubMed          Journal:  Am J Hypertens        ISSN： 0895-7061            Impact factor:   2.689


  39 in total

1.  A versatile gene-based test for genome-wide association studies.

Authors:  Jimmy Z Liu; Allan F McRae; Dale R Nyholt; Sarah E Medland; Naomi R Wray; Kevin M Brown; Nicholas K Hayward; Grant W Montgomery; Peter M Visscher; Nicholas G Martin; Stuart Macgregor
Journal:  Am J Hum Genet       Date:  2010-07-09       Impact factor: 11.025

2.  Vitamin D pathway gene variants and prostate cancer prognosis.

Authors:  Sarah K Holt; Erika M Kwon; Joseph S Koopmeiners; Daniel W Lin; Ziding Feng; Elaine A Ostrander; Ulrike Peters; Janet L Stanford
Journal:  Prostate       Date:  2010-09-15       Impact factor: 4.104

3.  Common genetic variants in the vitamin D pathway including genome-wide associated variants are not associated with breast cancer risk among Chinese women.

Authors:  Tsogzolmaa Dorjgochoo; Ryan Delahanty; Wei Lu; Jirong Long; Qiuyin Cai; Ying Zheng; Kai Gu; Yu-Tang Gao; Wei Zheng; Xiao Ou Shu
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2011-08-09       Impact factor: 4.254

4.  Vitamin D-associated polymorphisms are related to insulin resistance and vitamin D deficiency in polycystic ovary syndrome.

Authors:  Elisabeth Wehr; Olivia Trummer; Albrecht Giuliani; Hans-Jürgen Gruber; Thomas R Pieber; Barbara Obermayer-Pietsch
Journal:  Eur J Endocrinol       Date:  2011-03-09       Impact factor: 6.664

5.  Polymorphisms in vitamin D metabolism related genes and risk of multiple sclerosis.

Authors:  K Claire Simon; Kassandra L Munger; Alberto Ascherio
Journal:  Mult Scler       Date:  2009-12-09       Impact factor: 6.312

6.  Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension.

Authors:  Sandosh Padmanabhan; Olle Melander; Toby Johnson; Anna Maria Di Blasio; Wai K Lee; Davide Gentilini; Claire E Hastie; Cristina Menni; Maria Cristina Monti; Christian Delles; Stewart Laing; Barbara Corso; Gerjan Navis; Arjan J Kwakernaak; Pim van der Harst; Murielle Bochud; Marc Maillard; Michel Burnier; Thomas Hedner; Sverre Kjeldsen; Björn Wahlstrand; Marketa Sjögren; Cristiano Fava; Martina Montagnana; Elisa Danese; Ole Torffvit; Bo Hedblad; Harold Snieder; John M C Connell; Morris Brown; Nilesh J Samani; Martin Farrall; Giancarlo Cesana; Giuseppe Mancia; Stefano Signorini; Guido Grassi; Susana Eyheramendy; H Erich Wichmann; Maris Laan; David P Strachan; Peter Sever; Denis Colm Shields; Alice Stanton; Peter Vollenweider; Alexander Teumer; Henry Völzke; Rainer Rettig; Christopher Newton-Cheh; Pankaj Arora; Feng Zhang; Nicole Soranzo; Timothy D Spector; Gavin Lucas; Sekar Kathiresan; David S Siscovick; Jian'an Luan; Ruth J F Loos; Nicholas J Wareham; Brenda W Penninx; Ilja M Nolte; Martin McBride; William H Miller; Stuart A Nicklin; Andrew H Baker; Delyth Graham; Robert A McDonald; Jill P Pell; Naveed Sattar; Paul Welsh; Patricia Munroe; Mark J Caulfield; Alberto Zanchetti; Anna F Dominiczak
Journal:  PLoS Genet       Date:  2010-10-28       Impact factor: 5.917

7.  Genome-wide association study of blood pressure and hypertension.

Authors:  Daniel Levy; Georg B Ehret; Kenneth Rice; Germaine C Verwoert; Lenore J Launer; Abbas Dehghan; Nicole L Glazer; Alanna C Morrison; Andrew D Johnson; Thor Aspelund; Yurii Aulchenko; Thomas Lumley; Anna Köttgen; Ramachandran S Vasan; Fernando Rivadeneira; Gudny Eiriksdottir; Xiuqing Guo; Dan E Arking; Gary F Mitchell; Francesco U S Mattace-Raso; Albert V Smith; Kent Taylor; Robert B Scharpf; Shih-Jen Hwang; Eric J G Sijbrands; Joshua Bis; Tamara B Harris; Santhi K Ganesh; Christopher J O'Donnell; Albert Hofman; Jerome I Rotter; Josef Coresh; Emelia J Benjamin; André G Uitterlinden; Gerardo Heiss; Caroline S Fox; Jacqueline C M Witteman; Eric Boerwinkle; Thomas J Wang; Vilmundur Gudnason; Martin G Larson; Aravinda Chakravarti; Bruce M Psaty; Cornelia M van Duijn
Journal:  Nat Genet       Date:  2009-05-10       Impact factor: 38.330

8.  Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.

Authors:  Louise V Wain; Germaine C Verwoert; Paul F O'Reilly; Gang Shi; Toby Johnson; Andrew D Johnson; Murielle Bochud; Kenneth M Rice; Peter Henneman; Albert V Smith; Georg B Ehret; Najaf Amin; Martin G Larson; Vincent Mooser; David Hadley; Marcus Dörr; Joshua C Bis; Thor Aspelund; Tõnu Esko; A Cecile J W Janssens; Jing Hua Zhao; Simon Heath; Maris Laan; Jingyuan Fu; Giorgio Pistis; Jian'an Luan; Pankaj Arora; Gavin Lucas; Nicola Pirastu; Irene Pichler; Anne U Jackson; Rebecca J Webster; Feng Zhang; John F Peden; Helena Schmidt; Toshiko Tanaka; Harry Campbell; Wilmar Igl; Yuri Milaneschi; Jouke-Jan Hottenga; Veronique Vitart; Daniel I Chasman; Stella Trompet; Jennifer L Bragg-Gresham; Behrooz Z Alizadeh; John C Chambers; Xiuqing Guo; Terho Lehtimäki; Brigitte Kühnel; Lorna M Lopez; Ozren Polašek; Mladen Boban; Christopher P Nelson; Alanna C Morrison; Vasyl Pihur; Santhi K Ganesh; Albert Hofman; Suman Kundu; Francesco U S Mattace-Raso; Fernando Rivadeneira; Eric J G Sijbrands; Andre G Uitterlinden; Shih-Jen Hwang; Ramachandran S Vasan; Thomas J Wang; Sven Bergmann; Peter Vollenweider; Gérard Waeber; Jaana Laitinen; Anneli Pouta; Paavo Zitting; Wendy L McArdle; Heyo K Kroemer; Uwe Völker; Henry Völzke; Nicole L Glazer; Kent D Taylor; Tamara B Harris; Helene Alavere; Toomas Haller; Aime Keis; Mari-Liis Tammesoo; Yurii Aulchenko; Inês Barroso; Kay-Tee Khaw; Pilar Galan; Serge Hercberg; Mark Lathrop; Susana Eyheramendy; Elin Org; Siim Sõber; Xiaowen Lu; Ilja M Nolte; Brenda W Penninx; Tanguy Corre; Corrado Masciullo; Cinzia Sala; Leif Groop; Benjamin F Voight; Olle Melander; Christopher J O'Donnell; Veikko Salomaa; Adamo Pio d'Adamo; Antonella Fabretto; Flavio Faletra; Sheila Ulivi; Fabiola M Del Greco; Maurizio Facheris; Francis S Collins; Richard N Bergman; John P Beilby; Joseph Hung; A William Musk; Massimo Mangino; So-Youn Shin; Nicole Soranzo; Hugh Watkins; Anuj Goel; Anders Hamsten; Pierre Gider; Marisa Loitfelder; Marion Zeginigg; Dena Hernandez; Samer S Najjar; Pau Navarro; Sarah H Wild; Anna Maria Corsi; Andrew Singleton; Eco J C de Geus; Gonneke Willemsen; Alex N Parker; Lynda M Rose; Brendan Buckley; David Stott; Marco Orru; Manuela Uda; Melanie M van der Klauw; Weihua Zhang; Xinzhong Li; James Scott; Yii-Der Ida Chen; Gregory L Burke; Mika Kähönen; Jorma Viikari; Angela Döring; Thomas Meitinger; Gail Davies; John M Starr; Valur Emilsson; Andrew Plump; Jan H Lindeman; Peter A C 't Hoen; Inke R König; Janine F Felix; Robert Clarke; Jemma C Hopewell; Halit Ongen; Monique Breteler; Stéphanie Debette; Anita L Destefano; Myriam Fornage; Gary F Mitchell; Nicholas L Smith; Hilma Holm; Kari Stefansson; Gudmar Thorleifsson; Unnur Thorsteinsdottir; Nilesh J Samani; Michael Preuss; Igor Rudan; Caroline Hayward; Ian J Deary; H-Erich Wichmann; Olli T Raitakari; Walter Palmas; Jaspal S Kooner; Ronald P Stolk; J Wouter Jukema; Alan F Wright; Dorret I Boomsma; Stefania Bandinelli; Ulf B Gyllensten; James F Wilson; Luigi Ferrucci; Reinhold Schmidt; Martin Farrall; Tim D Spector; Lyle J Palmer; Jaakko Tuomilehto; Arne Pfeufer; Paolo Gasparini; David Siscovick; David Altshuler; Ruth J F Loos; Daniela Toniolo; Harold Snieder; Christian Gieger; Pierre Meneton; Nicholas J Wareham; Ben A Oostra; Andres Metspalu; Lenore Launer; Rainer Rettig; David P Strachan; Jacques S Beckmann; Jacqueline C M Witteman; Jeanette Erdmann; Ko Willems van Dijk; Eric Boerwinkle; Michael Boehnke; Paul M Ridker; Marjo-Riitta Jarvelin; Aravinda Chakravarti; Goncalo R Abecasis; Vilmundur Gudnason; Christopher Newton-Cheh; Daniel Levy; Patricia B Munroe; Bruce M Psaty; Mark J Caulfield; Dabeeru C Rao; Martin D Tobin; Paul Elliott; Cornelia M van Duijn
Journal:  Nat Genet       Date:  2011-09-11       Impact factor: 38.330

9.  Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.

Authors:  Georg B Ehret; Patricia B Munroe; Kenneth M Rice; Murielle Bochud; Andrew D Johnson; Daniel I Chasman; Albert V Smith; Martin D Tobin; Germaine C Verwoert; Shih-Jen Hwang; Vasyl Pihur; Peter Vollenweider; Paul F O'Reilly; Najaf Amin; Jennifer L Bragg-Gresham; Alexander Teumer; Nicole L Glazer; Lenore Launer; Jing Hua Zhao; Yurii Aulchenko; Simon Heath; Siim Sõber; Afshin Parsa; Jian'an Luan; Pankaj Arora; Abbas Dehghan; Feng Zhang; Gavin Lucas; Andrew A Hicks; Anne U Jackson; John F Peden; Toshiko Tanaka; Sarah H Wild; Igor Rudan; Wilmar Igl; Yuri Milaneschi; Alex N Parker; Cristiano Fava; John C Chambers; Ervin R Fox; Meena Kumari; Min Jin Go; Pim van der Harst; Wen Hong Linda Kao; Marketa Sjögren; D G Vinay; Myriam Alexander; Yasuharu Tabara; Sue Shaw-Hawkins; Peter H Whincup; Yongmei Liu; Gang Shi; Johanna Kuusisto; Bamidele Tayo; Mark Seielstad; Xueling Sim; Khanh-Dung Hoang Nguyen; Terho Lehtimäki; Giuseppe Matullo; Ying Wu; Tom R Gaunt; N Charlotte Onland-Moret; Matthew N Cooper; Carl G P Platou; Elin Org; Rebecca Hardy; Santosh Dahgam; Jutta Palmen; Veronique Vitart; Peter S Braund; Tatiana Kuznetsova; Cuno S P M Uiterwaal; Adebowale Adeyemo; Walter Palmas; Harry Campbell; Barbara Ludwig; Maciej Tomaszewski; Ioanna Tzoulaki; Nicholette D Palmer; Thor Aspelund; Melissa Garcia; Yen-Pei C Chang; Jeffrey R O'Connell; Nanette I Steinle; Diederick E Grobbee; Dan E Arking; Sharon L Kardia; Alanna C Morrison; Dena Hernandez; Samer Najjar; Wendy L McArdle; David Hadley; Morris J Brown; John M Connell; Aroon D Hingorani; Ian N M Day; Debbie A Lawlor; John P Beilby; Robert W Lawrence; Robert Clarke; Jemma C Hopewell; Halit Ongen; Albert W Dreisbach; Yali Li; J Hunter Young; Joshua C Bis; Mika Kähönen; Jorma Viikari; Linda S Adair; Nanette R Lee; Ming-Huei Chen; Matthias Olden; Cristian Pattaro; Judith A Hoffman Bolton; Anna Köttgen; Sven Bergmann; Vincent Mooser; Nish Chaturvedi; Timothy M Frayling; Muhammad Islam; Tazeen H Jafar; Jeanette Erdmann; Smita R Kulkarni; Stefan R Bornstein; Jürgen Grässler; Leif Groop; Benjamin F Voight; Johannes Kettunen; Philip Howard; Andrew Taylor; Simonetta Guarrera; Fulvio Ricceri; Valur Emilsson; Andrew Plump; Inês Barroso; Kay-Tee Khaw; Alan B Weder; Steven C Hunt; Yan V Sun; Richard N Bergman; Francis S Collins; Lori L Bonnycastle; Laura J Scott; Heather M Stringham; Leena Peltonen; Markus Perola; Erkki Vartiainen; Stefan-Martin Brand; Jan A Staessen; Thomas J Wang; Paul R Burton; Maria Soler Artigas; Yanbin Dong; Harold Snieder; Xiaoling Wang; Haidong Zhu; Kurt K Lohman; Megan E Rudock; Susan R Heckbert; Nicholas L Smith; Kerri L Wiggins; Ayo Doumatey; Daniel Shriner; Gudrun Veldre; Margus Viigimaa; Sanjay Kinra; Dorairaj Prabhakaran; Vikal Tripathy; Carl D Langefeld; Annika Rosengren; Dag S Thelle; Anna Maria Corsi; Andrew Singleton; Terrence Forrester; Gina Hilton; Colin A McKenzie; Tunde Salako; Naoharu Iwai; Yoshikuni Kita; Toshio Ogihara; Takayoshi Ohkubo; Tomonori Okamura; Hirotsugu Ueshima; Satoshi Umemura; Susana Eyheramendy; Thomas Meitinger; H-Erich Wichmann; Yoon Shin Cho; Hyung-Lae Kim; Jong-Young Lee; James Scott; Joban S Sehmi; Weihua Zhang; Bo Hedblad; Peter Nilsson; George Davey Smith; Andrew Wong; Narisu Narisu; Alena Stančáková; Leslie J Raffel; Jie Yao; Sekar Kathiresan; Christopher J O'Donnell; Stephen M Schwartz; M Arfan Ikram; W T Longstreth; Thomas H Mosley; Sudha Seshadri; Nick R G Shrine; Louise V Wain; Mario A Morken; Amy J Swift; Jaana Laitinen; Inga Prokopenko; Paavo Zitting; Jackie A Cooper; Steve E Humphries; John Danesh; Asif Rasheed; Anuj Goel; Anders Hamsten; Hugh Watkins; Stephan J L Bakker; Wiek H van Gilst; Charles S Janipalli; K Radha Mani; Chittaranjan S Yajnik; Albert Hofman; Francesco U S Mattace-Raso; Ben A Oostra; Ayse Demirkan; Aaron Isaacs; Fernando Rivadeneira; Edward G Lakatta; Marco Orru; Angelo Scuteri; Mika Ala-Korpela; Antti J Kangas; Leo-Pekka Lyytikäinen; Pasi Soininen; Taru Tukiainen; Peter Würtz; Rick Twee-Hee Ong; Marcus Dörr; Heyo K Kroemer; Uwe Völker; Henry Völzke; Pilar Galan; Serge Hercberg; Mark Lathrop; Diana Zelenika; Panos Deloukas; Massimo Mangino; Tim D Spector; Guangju Zhai; James F Meschia; Michael A Nalls; Pankaj Sharma; Janos Terzic; M V Kranthi Kumar; Matthew Denniff; Ewa Zukowska-Szczechowska; Lynne E Wagenknecht; F Gerald R Fowkes; Fadi J Charchar; Peter E H Schwarz; Caroline Hayward; Xiuqing Guo; Charles Rotimi; Michiel L Bots; Eva Brand; Nilesh J Samani; Ozren Polasek; Philippa J Talmud; Fredrik Nyberg; Diana Kuh; Maris Laan; Kristian Hveem; Lyle J Palmer; Yvonne T van der Schouw; Juan P Casas; Karen L Mohlke; Paolo Vineis; Olli Raitakari; Santhi K Ganesh; Tien Y Wong; E Shyong Tai; Richard S Cooper; Markku Laakso; Dabeeru C Rao; Tamara B Harris; Richard W Morris; Anna F Dominiczak; Mika Kivimaki; Michael G Marmot; Tetsuro Miki; Danish Saleheen; Giriraj R Chandak; Josef Coresh; Gerjan Navis; Veikko Salomaa; Bok-Ghee Han; Xiaofeng Zhu; Jaspal S Kooner; Olle Melander; Paul M Ridker; Stefania Bandinelli; Ulf B Gyllensten; Alan F Wright; James F Wilson; Luigi Ferrucci; Martin Farrall; Jaakko Tuomilehto; Peter P Pramstaller; Roberto Elosua; Nicole Soranzo; Eric J G Sijbrands; David Altshuler; Ruth J F Loos; Alan R Shuldiner; Christian Gieger; Pierre Meneton; Andre G Uitterlinden; Nicholas J Wareham; Vilmundur Gudnason; Jerome I Rotter; Rainer Rettig; Manuela Uda; David P Strachan; Jacqueline C M Witteman; Anna-Liisa Hartikainen; Jacques S Beckmann; Eric Boerwinkle; Ramachandran S Vasan; Michael Boehnke; Martin G Larson; Marjo-Riitta Järvelin; Bruce M Psaty; Gonçalo R Abecasis; Aravinda Chakravarti; Paul Elliott; Cornelia M van Duijn; Christopher Newton-Cheh; Daniel Levy; Mark J Caulfield; Toby Johnson
Journal:  Nature       Date:  2011-09-11       Impact factor: 49.962

10.  Genome-wide association study identifies eight loci associated with blood pressure.

Authors:  Christopher Newton-Cheh; Toby Johnson; Vesela Gateva; Martin D Tobin; Murielle Bochud; Lachlan Coin; Samer S Najjar; Jing Hua Zhao; Simon C Heath; Susana Eyheramendy; Konstantinos Papadakis; Benjamin F Voight; Laura J Scott; Feng Zhang; Martin Farrall; Toshiko Tanaka; Chris Wallace; John C Chambers; Kay-Tee Khaw; Peter Nilsson; Pim van der Harst; Silvia Polidoro; Diederick E Grobbee; N Charlotte Onland-Moret; Michiel L Bots; Louise V Wain; Katherine S Elliott; Alexander Teumer; Jian'an Luan; Gavin Lucas; Johanna Kuusisto; Paul R Burton; David Hadley; Wendy L McArdle; Morris Brown; Anna Dominiczak; Stephen J Newhouse; Nilesh J Samani; John Webster; Eleftheria Zeggini; Jacques S Beckmann; Sven Bergmann; Noha Lim; Kijoung Song; Peter Vollenweider; Gerard Waeber; Dawn M Waterworth; Xin Yuan; Leif Groop; Marju Orho-Melander; Alessandra Allione; Alessandra Di Gregorio; Simonetta Guarrera; Salvatore Panico; Fulvio Ricceri; Valeria Romanazzi; Carlotta Sacerdote; Paolo Vineis; Inês Barroso; Manjinder S Sandhu; Robert N Luben; Gabriel J Crawford; Pekka Jousilahti; Markus Perola; Michael Boehnke; Lori L Bonnycastle; Francis S Collins; Anne U Jackson; Karen L Mohlke; Heather M Stringham; Timo T Valle; Cristen J Willer; Richard N Bergman; Mario A Morken; Angela Döring; Christian Gieger; Thomas Illig; Thomas Meitinger; Elin Org; Arne Pfeufer; H Erich Wichmann; Sekar Kathiresan; Jaume Marrugat; Christopher J O'Donnell; Stephen M Schwartz; David S Siscovick; Isaac Subirana; Nelson B Freimer; Anna-Liisa Hartikainen; Mark I McCarthy; Paul F O'Reilly; Leena Peltonen; Anneli Pouta; Paul E de Jong; Harold Snieder; Wiek H van Gilst; Robert Clarke; Anuj Goel; Anders Hamsten; John F Peden; Udo Seedorf; Ann-Christine Syvänen; Giovanni Tognoni; Edward G Lakatta; Serena Sanna; Paul Scheet; David Schlessinger; Angelo Scuteri; Marcus Dörr; Florian Ernst; Stephan B Felix; Georg Homuth; Roberto Lorbeer; Thorsten Reffelmann; Rainer Rettig; Uwe Völker; Pilar Galan; Ivo G Gut; Serge Hercberg; G Mark Lathrop; Diana Zelenika; Panos Deloukas; Nicole Soranzo; Frances M Williams; Guangju Zhai; Veikko Salomaa; Markku Laakso; Roberto Elosua; Nita G Forouhi; Henry Völzke; Cuno S Uiterwaal; Yvonne T van der Schouw; Mattijs E Numans; Giuseppe Matullo; Gerjan Navis; Göran Berglund; Sheila A Bingham; Jaspal S Kooner; John M Connell; Stefania Bandinelli; Luigi Ferrucci; Hugh Watkins; Tim D Spector; Jaakko Tuomilehto; David Altshuler; David P Strachan; Maris Laan; Pierre Meneton; Nicholas J Wareham; Manuela Uda; Marjo-Riitta Jarvelin; Vincent Mooser; Olle Melander; Ruth J F Loos; Paul Elliott; Gonçalo R Abecasis; Mark Caulfield; Patricia B Munroe
Journal:  Nat Genet       Date:  2009-05-10       Impact factor: 38.330
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  12 in total

1.  Meta-Analysis of the Association Between the rs228570 Vitamin D Receptor Gene Polymorphism and Arterial Hypertension Risk.

Authors:  Ivone F O C Nunes; Ana A C M Cavalcante; Marcus V O B Alencar; Marcos D F Carvalho; José L R Sarmento; Nayra S C C A Teixeira; Adriana A Paiva; Lídia R Carvalho; Leopoldo F M Nascimento; Maria S P Cruz; Marcelo M Rogero; Andréia C B Lima; Cecilia M R G Carvalho
Journal:  Adv Nutr       Date:  2020-09-01       Impact factor: 8.701

2.  A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.

Authors:  Yun Ju Sung; Lisa de Las Fuentes; Thomas W Winkler; Daniel I Chasman; Amy R Bentley; Aldi T Kraja; Ioanna Ntalla; Helen R Warren; Xiuqing Guo; Karen Schwander; Alisa K Manning; Michael R Brown; Hugues Aschard; Mary F Feitosa; Nora Franceschini; Yingchang Lu; Ching-Yu Cheng; Xueling Sim; Dina Vojinovic; Jonathan Marten; Solomon K Musani; Tuomas O Kilpeläinen; Melissa A Richard; Stella Aslibekyan; Traci M Bartz; Rajkumar Dorajoo; Changwei Li; Yongmei Liu; Tuomo Rankinen; Albert Vernon Smith; Salman M Tajuddin; Bamidele O Tayo; Wei Zhao; Yanhua Zhou; Nana Matoba; Tamar Sofer; Maris Alver; Marzyeh Amini; Mathilde Boissel; Jin Fang Chai; Xu Chen; Jasmin Divers; Ilaria Gandin; Chuan Gao; Franco Giulianini; Anuj Goel; Sarah E Harris; Fernando P Hartwig; Meian He; Andrea R V R Horimoto; Fang-Chi Hsu; Anne U Jackson; Candace M Kammerer; Anuradhani Kasturiratne; Pirjo Komulainen; Brigitte Kühnel; Karin Leander; Wen-Jane Lee; Keng-Hung Lin; Jian'an Luan; Leo-Pekka Lyytikäinen; Colin A McKenzie; Christopher P Nelson; Raymond Noordam; Robert A Scott; Wayne H H Sheu; Alena Stančáková; Fumihiko Takeuchi; Peter J van der Most; Tibor V Varga; Robert J Waken; Heming Wang; Yajuan Wang; Erin B Ware; Stefan Weiss; Wanqing Wen; Lisa R Yanek; Weihua Zhang; Jing Hua Zhao; Saima Afaq; Tamuno Alfred; Najaf Amin; Dan E Arking; Tin Aung; R Graham Barr; Lawrence F Bielak; Eric Boerwinkle; Erwin P Bottinger; Peter S Braund; Jennifer A Brody; Ulrich Broeckel; Brian Cade; Archie Campbell; Mickaël Canouil; Aravinda Chakravarti; Massimiliano Cocca; Francis S Collins; John M Connell; Renée de Mutsert; H Janaka de Silva; Marcus Dörr; Qing Duan; Charles B Eaton; Georg Ehret; Evangelos Evangelou; Jessica D Faul; Nita G Forouhi; Oscar H Franco; Yechiel Friedlander; He Gao; Bruna Gigante; C Charles Gu; Preeti Gupta; Saskia P Hagenaars; Tamara B Harris; Jiang He; Sami Heikkinen; Chew-Kiat Heng; Albert Hofman; Barbara V Howard; Steven C Hunt; Marguerite R Irvin; Yucheng Jia; Tomohiro Katsuya; Joel Kaufman; Nicola D Kerrison; Chiea Chuen Khor; Woon-Puay Koh; Heikki A Koistinen; Charles B Kooperberg; Jose E Krieger; Michiaki Kubo; Zoltan Kutalik; Johanna Kuusisto; Timo A Lakka; Carl D Langefeld; Claudia Langenberg; Lenore J Launer; Joseph H Lee; Benjamin Lehne; Daniel Levy; Cora E Lewis; Yize Li; Sing Hui Lim; Ching-Ti Liu; Jianjun Liu; Jingmin Liu; Yeheng Liu; Marie Loh; Kurt K Lohman; Tin Louie; Reedik Mägi; Koichi Matsuda; Thomas Meitinger; Andres Metspalu; Lili Milani; Yukihide Momozawa; Thomas H Mosley; Mike A Nalls; Ubaydah Nasri; Jeff R O'Connell; Adesola Ogunniyi; Walter R Palmas; Nicholette D Palmer; James S Pankow; Nancy L Pedersen; Annette Peters; Patricia A Peyser; Ozren Polasek; David Porteous; Olli T Raitakari; Frida Renström; Treva K Rice; Paul M Ridker; Antonietta Robino; Jennifer G Robinson; Lynda M Rose; Igor Rudan; Charumathi Sabanayagam; Babatunde L Salako; Kevin Sandow; Carsten O Schmidt; Pamela J Schreiner; William R Scott; Peter Sever; Mario Sims; Colleen M Sitlani; Blair H Smith; Jennifer A Smith; Harold Snieder; John M Starr; Konstantin Strauch; Hua Tang; Kent D Taylor; Yik Ying Teo; Yih Chung Tham; André G Uitterlinden; Melanie Waldenberger; Lihua Wang; Ya Xing Wang; Wen Bin Wei; Gregory Wilson; Mary K Wojczynski; Yong-Bing Xiang; Jie Yao; Jian-Min Yuan; Alan B Zonderman; Diane M Becker; Michael Boehnke; Donald W Bowden; John C Chambers; Yii-Der Ida Chen; David R Weir; Ulf de Faire; Ian J Deary; Tõnu Esko; Martin Farrall; Terrence Forrester; Barry I Freedman; Philippe Froguel; Paolo Gasparini; Christian Gieger; Bernardo Lessa Horta; Yi-Jen Hung; Jost Bruno Jonas; Norihiro Kato; Jaspal S Kooner; Markku Laakso; Terho Lehtimäki; Kae-Woei Liang; Patrik K E Magnusson; Albertine J Oldehinkel; Alexandre C Pereira; Thomas Perls; Rainer Rauramaa; Susan Redline; Rainer Rettig; Nilesh J Samani; James Scott; Xiao-Ou Shu; Pim van der Harst; Lynne E Wagenknecht; Nicholas J Wareham; Hugh Watkins; Ananda R Wickremasinghe; Tangchun Wu; Yoichiro Kamatani; Cathy C Laurie; Claude Bouchard; Richard S Cooper; Michele K Evans; Vilmundur Gudnason; James Hixson; Sharon L R Kardia; Stephen B Kritchevsky; Bruce M Psaty; Rob M van Dam; Donna K Arnett; Dennis O Mook-Kanamori; Myriam Fornage; Ervin R Fox; Caroline Hayward; Cornelia M van Duijn; E Shyong Tai; Tien Yin Wong; Ruth J F Loos; Alex P Reiner; Charles N Rotimi; Laura J Bierut; Xiaofeng Zhu; L Adrienne Cupples; Michael A Province; Jerome I Rotter; Paul W Franks; Kenneth Rice; Paul Elliott; Mark J Caulfield; W James Gauderman; Patricia B Munroe; Dabeeru C Rao; Alanna C Morrison
Journal:  Hum Mol Genet       Date:  2019-08-01       Impact factor: 6.150

3.  Vitamin D and Atherosclerotic Cardiovascular Disease.

Authors:  Thomas Hiemstra; Kenneth Lim; Ravi Thadhani; JoAnn E Manson
Journal:  J Clin Endocrinol Metab       Date:  2019-04-04       Impact factor: 5.958

Review 4.  Vitamin D and cardiovascular disease prevention.

Authors:  Stefan Pilz; Nicolas Verheyen; Martin R Grübler; Andreas Tomaschitz; Winfried März
Journal:  Nat Rev Cardiol       Date:  2016-05-06       Impact factor: 32.419

5.  Vitamin D3 supplementation does not modify cardiovascular risk profile of adults with inadequate vitamin D status.

Authors:  Eric Seibert; Ulrike Lehmann; Annett Riedel; Christof Ulrich; Frank Hirche; Corinna Brandsch; Jutta Dierkes; Matthias Girndt; Gabriele I Stangl
Journal:  Eur J Nutr       Date:  2015-11-30       Impact factor: 5.614

6.  Vitamin D receptor gene polymorphisms and plasma renin activity in essential hypertensive individuals.

Authors:  S Cottone; L Guarino; R Arsena; C Scazzone; F Tornese; M Guarneri; C Guglielmo; A Bono; G Mulè
Journal:  J Hum Hypertens       Date:  2014-12-11       Impact factor: 3.012

Review 7.  Vitamin-D concentrations, cardiovascular risk and events - a review of epidemiological evidence.

Authors:  Martin Robert Grübler; Winfried März; Stefan Pilz; Tanja B Grammer; Christian Trummer; Christian Müllner; Verena Schwetz; Marlene Pandis; Nicolas Verheyen; Andreas Tomaschitz; Antonella Fiordelisi; Daniela Laudisio; Ersilia Cipolletta; Guido Iaccarino
Journal:  Rev Endocr Metab Disord       Date:  2017-06       Impact factor: 6.514

8.  Rare variants in fox-1 homolog A (RBFOX1) are associated with lower blood pressure.

Authors:  Karen Y He; Heming Wang; Brian E Cade; Priyanka Nandakumar; Ayush Giri; Erin B Ware; Jeffrey Haessler; Jingjing Liang; Jennifer A Smith; Nora Franceschini; Thu H Le; Charles Kooperberg; Todd L Edwards; Sharon L R Kardia; Xihong Lin; Aravinda Chakravarti; Susan Redline; Xiaofeng Zhu
Journal:  PLoS Genet       Date:  2017-03-27       Impact factor: 5.917

9.  Exome sequencing in pooled DNA samples to identify maternal pre-eclampsia risk variants.

Authors:  Tea Kaartokallio; Jingwen Wang; Seppo Heinonen; Eero Kajantie; Katja Kivinen; Anneli Pouta; Paul Gerdhem; Hong Jiao; Juha Kere; Hannele Laivuori
Journal:  Sci Rep       Date:  2016-07-07       Impact factor: 4.379

10.  Admixture mapping in the Hispanic Community Health Study/Study of Latinos reveals regions of genetic associations with blood pressure traits.

Authors:  Tamar Sofer; Leslie J Baier; Sharon R Browning; Timothy A Thornton; Gregory A Talavera; Sylvia Wassertheil-Smoller; Martha L Daviglus; Robert Hanson; Sayuko Kobes; Richard S Cooper; Jianwen Cai; Daniel Levy; Alex P Reiner; Nora Franceschini
Journal:  PLoS One       Date:  2017-11-20       Impact factor: 3.240
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