Literature DB >> 24684743

Reconstruction after skin cancer excision through a dermal induction template: our experience.

Maria G Onesti1, Pasquale Fino1, Paolo Fioramonti1, Vittoria Amorosi1, Nicolò Scuderi1.   

Abstract

Dermal substitutes offer alternative approaches for wounds of all thicknesses where sufficient donation sites are not available for self-grafts. Several dermal substitutes are described in literature. This study included 20 patients treated with a dermal induction template after the removal of malignant skin cancers situated in various parts of the body. The participants were especially aged patients with multiple skin cancers, and complex clinical conditions, often affected by pathologies such as cardiopathy, diabetes mellitus, and hypercholesterolaemia, and receiving pharmacological multi-therapies, particularly antiplatelets and anticoagulants. In many of these patients, the general complex clinical picture provided significant contraindication for complex reconstructive surgery because of the high risk involved. All patients achieved complete healing about 8 weeks after the first surgery. By using a dermal induction template, it was possible to cover substantial loss of substances without the need of autologous tissue, with smoother and less apparent scar, minor occurrence of hypertrophic and retracted scars, better flexibility of healed skin and therefore a better result from an aesthetic point of view.
© 2014 The Authors. International Wound Journal © 2014 Medicalhelplines.com Inc and John Wiley & Sons Ltd.

Entities:  

Keywords:  Basal cell carcinoma; Dermal induction template; Hyalomatrix PA; Skin cancers; Squamous cell carcinoma

Mesh:

Year:  2014        PMID: 24684743      PMCID: PMC7949901          DOI: 10.1111/iwj.12255

Source DB:  PubMed          Journal:  Int Wound J        ISSN: 1742-4801            Impact factor:   3.315


  14 in total

Review 1.  Classification and pathophysiology of skin grafts.

Authors:  Andrea Andreassi; Roberta Bilenchi; Maurizio Biagioli; Carlo D'Aniello
Journal:  Clin Dermatol       Date:  2005 Jul-Aug       Impact factor: 3.541

2.  Visual analogue scale scoring and ranking: a suitable and sensitive method for assessing scar quality?

Authors:  Jonathan A L Duncan; Jeremy S Bond; Tracey Mason; Anna Ludlow; Peter Cridland; Sharon O'Kane; Mark W J Ferguson
Journal:  Plast Reconstr Surg       Date:  2006-09-15       Impact factor: 4.730

3.  An alternative approach for soft-tissue coverage of a complex wound in the foot and ankle with vacuum-assisted closure over artificial dermis and subsequent skin graft.

Authors:  Lee L Q Pu
Journal:  J Plast Reconstr Aesthet Surg       Date:  2008-11-21       Impact factor: 2.740

Review 4.  A review of tissue-engineered skin bioconstructs available for skin reconstruction.

Authors:  Rostislav V Shevchenko; Stuart L James; S Elizabeth James
Journal:  J R Soc Interface       Date:  2009-10-28       Impact factor: 4.118

5.  Integra artificial skin in the management of severe tissue defects, including bone exposure, in injured children.

Authors:  Philippe Violas; Abdelazis Abid; Philippe Darodes; Philippe Galinier; Jérome Sales de Gauzy; Jean-Philippe Cahuzac
Journal:  J Pediatr Orthop B       Date:  2005-09       Impact factor: 1.041

6.  Reconstruction of burn scar of the upper extremities with artificial skin.

Authors:  T D Chou; S L Chen; T W Lee; S G Chen; T Y Cheng; C H Lee; T M Chen; H J Wang
Journal:  Plast Reconstr Surg       Date:  2001-08       Impact factor: 4.730

Review 7.  Skin cancers and their etiologies.

Authors:  Ashfaq A Marghoob
Journal:  Semin Cutan Med Surg       Date:  2011-12

8.  A comparison of tissue-engineered hyaluronic acid dermal matrices in a human wound model.

Authors:  Richard D Price; Victoria Das-Gupta; Irene M Leigh; Harshad A Navsaria
Journal:  Tissue Eng       Date:  2006-10

9.  The use of the artificial dermis (Integra) in combination with vacuum assisted closure for reconstruction of an extensive burn scar--a case report.

Authors:  M Leffler; R E Horch; A Dragu; A D Bach
Journal:  J Plast Reconstr Aesthet Surg       Date:  2009-06-11       Impact factor: 2.740

Review 10.  Current scales for assessing human scarring: a review.

Authors:  Piyush Durani; D A McGrouther; M W J Ferguson
Journal:  J Plast Reconstr Aesthet Surg       Date:  2009-03-20       Impact factor: 2.740

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  3 in total

Review 1.  Skin cancers and dermal substitutes: Is it safe? Review of the literature and presentation of a 2-stage surgical protocol for the treatment of non-melanoma skin cancers of the head in fragile patients.

Authors:  Marco Marcasciano; Marco Mazzocchi; Juste Kaciulyte; Noemi Spissu; Donato Casella; Diego Ribuffo; Luca Andrea Dessy
Journal:  Int Wound J       Date:  2018-06-04       Impact factor: 3.315

2.  Use of Hyaluronic Acid-Based Biological Bilaminar Matrix in Wound Bed Preparation: A Case Series.

Authors:  Richard Simman; Walid Mari; Sara Younes; Michael Wilson
Journal:  Eplasty       Date:  2018-02-22

3.  Use of Hyaluronic Acid-Based Biological Bilaminar Matrix in Wound Bed Preparation: A Case Series.

Authors:  Richard Simman; Walid Mari; Sara Younes; Michael Wilson
Journal:  Eplasty       Date:  2018-04-26
  3 in total

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