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Literature DB >> 24679539

Individualized medicine from prewomb to tomb.

Abstract

That each of us is truly biologically unique, extending to even monozygotic, "identical" twins, is not fully appreciated. Now that it is possible to perform a comprehensive "omic" assessment of an individual, including one's DNA and RNA sequence and at least some characterization of one's proteome, metabolome, microbiome, autoantibodies, and epigenome, it has become abundantly clear that each of us has truly one-of-a-kind biological content. Well beyond the allure of the matchless fingerprint or snowflake concept, these singular, individual data and information set up a remarkable and unprecedented opportunity to improve medical treatment and develop preventive strategies to preserve health.

Entities: CellLine Chemical Disease Gene Mutation Species

Mesh：

Year: 2014 PMID： 24679539 PMCID： PMC3995127 DOI： 10.1016/j.cell.2014.02.012

Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582

93 in total

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Review 3. Cell-free nucleic acids as biomarkers in cancer patients.

Authors: Heidi Schwarzenbach; Dave S B Hoon; Klaus Pantel
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4. Whole-genome sequencing and social-network analysis of a tuberculosis outbreak.

Authors: Jennifer L Gardy; James C Johnston; Shannan J Ho Sui; Victoria J Cook; Lena Shah; Elizabeth Brodkin; Shirley Rempel; Richard Moore; Yongjun Zhao; Robert Holt; Richard Varhol; Inanc Birol; Marcus Lem; Meenu K Sharma; Kevin Elwood; Steven J M Jones; Fiona S L Brinkman; Robert C Brunham; Patrick Tang
Journal: N Engl J Med Date: 2011-02-24 Impact factor: 91.245

5. Transgenerational epigenetic instability is a source of novel methylation variants.

Authors: Robert J Schmitz; Matthew D Schultz; Mathew G Lewsey; Ronan C O'Malley; Mark A Urich; Ondrej Libiger; Nicholas J Schork; Joseph R Ecker
Journal: Science Date: 2011-09-15 Impact factor: 47.728

6. Enterotypes of the human gut microbiome.

Authors: Manimozhiyan Arumugam; Jeroen Raes; Eric Pelletier; Denis Le Paslier; Takuji Yamada; Daniel R Mende; Gabriel R Fernandes; Julien Tap; Thomas Bruls; Jean-Michel Batto; Marcelo Bertalan; Natalia Borruel; Francesc Casellas; Leyden Fernandez; Laurent Gautier; Torben Hansen; Masahira Hattori; Tetsuya Hayashi; Michiel Kleerebezem; Ken Kurokawa; Marion Leclerc; Florence Levenez; Chaysavanh Manichanh; H Bjørn Nielsen; Trine Nielsen; Nicolas Pons; Julie Poulain; Junjie Qin; Thomas Sicheritz-Ponten; Sebastian Tims; David Torrents; Edgardo Ugarte; Erwin G Zoetendal; Jun Wang; Francisco Guarner; Oluf Pedersen; Willem M de Vos; Søren Brunak; Joel Doré; María Antolín; François Artiguenave; Hervé M Blottiere; Mathieu Almeida; Christian Brechot; Carlos Cara; Christian Chervaux; Antonella Cultrone; Christine Delorme; Gérard Denariaz; Rozenn Dervyn; Konrad U Foerstner; Carsten Friss; Maarten van de Guchte; Eric Guedon; Florence Haimet; Wolfgang Huber; Johan van Hylckama-Vlieg; Alexandre Jamet; Catherine Juste; Ghalia Kaci; Jan Knol; Omar Lakhdari; Severine Layec; Karine Le Roux; Emmanuelle Maguin; Alexandre Mérieux; Raquel Melo Minardi; Christine M'rini; Jean Muller; Raish Oozeer; Julian Parkhill; Pierre Renault; Maria Rescigno; Nicolas Sanchez; Shinichi Sunagawa; Antonio Torrejon; Keith Turner; Gaetana Vandemeulebrouck; Encarna Varela; Yohanan Winogradsky; Georg Zeller; Jean Weissenbach; S Dusko Ehrlich; Peer Bork
Journal: Nature Date: 2011-04-20 Impact factor: 49.962

Review 7. The importance of phase information for human genomics.

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8. Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib.

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Journal: N Engl J Med Date: 2012-02-23 Impact factor: 91.245

Review 9. Hallmarks of cancer: the next generation.

Authors: Douglas Hanahan; Robert A Weinberg
Journal: Cell Date: 2011-03-04 Impact factor: 41.582

10. Making a definitive diagnosis: successful clinical application of whole exome sequencing in a child with intractable inflammatory bowel disease.

Authors: Elizabeth A Worthey; Alan N Mayer; Grant D Syverson; Daniel Helbling; Benedetta B Bonacci; Brennan Decker; Jaime M Serpe; Trivikram Dasu; Michael R Tschannen; Regan L Veith; Monica J Basehore; Ulrich Broeckel; Aoy Tomita-Mitchell; Marjorie J Arca; James T Casper; David A Margolis; David P Bick; Martin J Hessner; John M Routes; James W Verbsky; Howard J Jacob; David P Dimmock
Journal: Genet Med Date: 2011-03 Impact factor: 8.822

86 in total

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Authors: Andrew R Harper; Shalini Nayee; Eric J Topol
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Review 3. Precision Medicine: From Science To Value.

Authors: Geoffrey S Ginsburg; Kathryn A Phillips
Journal: Health Aff (Millwood) Date: 2018-05 Impact factor: 6.301

Review 4. An Individualized, Data-Driven Digital Approach for Precision Behavior Change.

Authors: Shannon Wongvibulsin; Seth S Martin; Suchi Saria; Scott L Zeger; Susan A Murphy
Journal: Am J Lifestyle Med Date: 2019-04-25

5. Aortic Waveform Analysis to Individualize Treatment in Heart Failure.

Authors: Peter Wohlfahrt; Vojtech Melenovsky; Margaret M Redfield; Thomas P Olson; Grace Lin; Sahar S Abdelmoneim; Bernhard Hametner; Siegfried Wassertheurer; Barry A Borlaug
Journal: Circ Heart Fail Date: 2017-02 Impact factor: 8.790

Review 6. The cysteine proteome.

Authors: Young-Mi Go; Joshua D Chandler; Dean P Jones
Journal: Free Radic Biol Med Date: 2015-04-03 Impact factor: 7.376