Literature DB >> 24661004

LRRK2: dropping (kinase) inhibitions and seeking an (immune) response.

Adamantios Mamais1, Mark R Cookson.   

Abstract

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Year:  2014        PMID： 24661004      PMCID： PMC4055502          DOI： 10.1111/jnc.12691

Source DB:  PubMed          Journal:  J Neurochem        ISSN： 0022-3042            Impact factor:   5.372


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  14 in total

1.  LRRK2 is involved in the IFN-gamma response and host response to pathogens.

Authors:  Agnès Gardet; Yair Benita; Chun Li; Bruce E Sands; Isabel Ballester; Christine Stevens; Joshua R Korzenik; John D Rioux; Mark J Daly; Ramnik J Xavier; Daniel K Podolsky
Journal:  J Immunol       Date:  2010-10-04       Impact factor: 5.422

2.  Neuroprotective role of ERK1/2 and ERK5 in a dopaminergic cell line under basal conditions and in response to oxidative stress.

Authors:  Jane E Cavanaugh; Juliann D Jaumotte; Joan M Lakoski; Michael J Zigmond
Journal:  J Neurosci Res       Date:  2006-11-01       Impact factor: 4.164

3.  Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration.

Authors:  Liya Qin; Xuefei Wu; Michelle L Block; Yuxin Liu; George R Breese; Jau-Shyong Hong; Darin J Knapp; Fulton T Crews
Journal:  Glia       Date:  2007-04-01       Impact factor: 7.452

4.  Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.

Authors:  Jeffrey C Barrett; Sarah Hansoul; Dan L Nicolae; Judy H Cho; Richard H Duerr; John D Rioux; Steven R Brant; Mark S Silverberg; Kent D Taylor; M Michael Barmada; Alain Bitton; Themistocles Dassopoulos; Lisa Wu Datta; Todd Green; Anne M Griffiths; Emily O Kistner; Michael T Murtha; Miguel D Regueiro; Jerome I Rotter; L Philip Schumm; A Hillary Steinhart; Stephan R Targan; Ramnik J Xavier; Cécile Libioulle; Cynthia Sandor; Mark Lathrop; Jacques Belaiche; Olivier Dewit; Ivo Gut; Simon Heath; Debby Laukens; Myriam Mni; Paul Rutgeerts; André Van Gossum; Diana Zelenika; Denis Franchimont; Jean-Pierre Hugot; Martine de Vos; Severine Vermeire; Edouard Louis; Lon R Cardon; Carl A Anderson; Hazel Drummond; Elaine Nimmo; Tariq Ahmad; Natalie J Prescott; Clive M Onnie; Sheila A Fisher; Jonathan Marchini; Jilur Ghori; Suzannah Bumpstead; Rhian Gwilliam; Mark Tremelling; Panos Deloukas; John Mansfield; Derek Jewell; Jack Satsangi; Christopher G Mathew; Miles Parkes; Michel Georges; Mark J Daly
Journal:  Nat Genet       Date:  2008-06-29       Impact factor: 38.330

5.  LRRK2 directly phosphorylates Akt1 as a possible physiological substrate: impairment of the kinase activity by Parkinson's disease-associated mutations.

Authors:  Etsuro Ohta; Fumitaka Kawakami; Makoto Kubo; Fumiya Obata
Journal:  FEBS Lett       Date:  2011-06-02       Impact factor: 4.124

6.  Genomewide association study of leprosy.

Authors:  Fu-Ren Zhang; Wei Huang; Shu-Min Chen; Liang-Dan Sun; Hong Liu; Yi Li; Yong Cui; Xiao-Xiao Yan; Hai-Tao Yang; Rong-De Yang; Tong-Sheng Chu; Chi Zhang; Lin Zhang; Jian-Wen Han; Gong-Qi Yu; Cheng Quan; Yong-Xiang Yu; Zheng Zhang; Ben-Qing Shi; Lian-Hua Zhang; Hui Cheng; Chang-Yuan Wang; Yan Lin; Hou-Feng Zheng; Xi-An Fu; Xian-Bo Zuo; Qiang Wang; Heng Long; Yi-Ping Sun; Yi-Lin Cheng; Hong-Qing Tian; Fu-Sheng Zhou; Hua-Xu Liu; Wen-Sheng Lu; Su-Min He; Wen-Li Du; Min Shen; Qi-Yi Jin; Ying Wang; Hui-Qi Low; Tantoso Erwin; Ning-Han Yang; Jin-Yong Li; Xin Zhao; Yue-Lin Jiao; Li-Guo Mao; Gang Yin; Zhen-Xia Jiang; Xiao-Dong Wang; Jing-Ping Yu; Zong-Hou Hu; Cui-Hua Gong; Yu-Qiang Liu; Rui-Yu Liu; De-Min Wang; Dong Wei; Jin-Xian Liu; Wei-Kun Cao; Hong-Zhong Cao; Yong-Ping Li; Wei-Guo Yan; Shi-Yu Wei; Kui-Jun Wang; Martin L Hibberd; Sen Yang; Xue-Jun Zhang; Jian-Jun Liu
Journal:  N Engl J Med       Date:  2009-12-16       Impact factor: 91.245

7.  Akt signal transduction dysfunction in Parkinson's disease.

Authors:  Suzanne Timmons; Meghan F Coakley; Aileen M Moloney; Cora O' Neill
Journal:  Neurosci Lett       Date:  2009-10-01       Impact factor: 3.046

8.  CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity.

Authors:  Han Seok Ko; Rachel Bailey; Wanli W Smith; Zhaohui Liu; Joo-Ho Shin; Yun-Il Lee; Yong-Jie Zhang; Haibing Jiang; Christopher A Ross; Darren J Moore; Cam Patterson; Leonard Petrucelli; Ted M Dawson; Valina L Dawson
Journal:  Proc Natl Acad Sci U S A       Date:  2009-02-05       Impact factor: 11.205

9.  Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures.

Authors:  Mansoureh Hakimi; Thirumahal Selvanantham; Erika Swinton; Ruth F Padmore; Youren Tong; Ghassan Kabbach; Katerina Venderova; Stephen E Girardin; Dennis E Bulman; Clemens R Scherzer; Matthew J LaVoie; Denis Gris; David S Park; Jonathan B Angel; Jie Shen; Dana J Philpott; Michael G Schlossmacher
Journal:  J Neural Transm (Vienna)       Date:  2011-05-07       Impact factor: 3.575

10.  The IkappaB kinase family phosphorylates the Parkinson's disease kinase LRRK2 at Ser935 and Ser910 during Toll-like receptor signaling.

Authors:  Nicolas Dzamko; Francisco Inesta-Vaquera; Jiazhen Zhang; Chengsong Xie; Huaibin Cai; Simon Arthur; Li Tan; Hwanguen Choi; Nathanael Gray; Philip Cohen; Patrick Pedrioli; Kristopher Clark; Dario R Alessi
Journal:  PLoS One       Date:  2012-06-18       Impact factor: 3.240
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  2 in total

1.  Leucine-Rich Repeat Kinase 2 (Lrrk2)-Sensitive Na+/K+ ATPase Activity in Dendritic Cells.

Authors:  Zohreh Hosseinzadeh; Yogesh Singh; Derya R Shimshek; Herman van der Putten; Carsten A Wagner; Florian Lang
Journal:  Sci Rep       Date:  2017-01-25       Impact factor: 4.379

2.  The kinase LRRK2 is differently expressed in chronic rhinosinusitis with and without nasal polyps.

Authors:  Yue Ma; Chunquan Zheng; Le Shi
Journal:  Clin Transl Allergy       Date:  2018-03-12       Impact factor: 5.871
  2 in total

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