Literature DB >> 24641889

Licensing of DNA replication, cancer, pluripotency and differentiation: an interlinked world?

S Champeris Tsaniras1, N Kanellakis2, I E Symeonidou3, P Nikolopoulou4, Z Lygerou5, S Taraviras6.   

Abstract

Recent findings provide evidence for a functional interplay between DNA replication and the seemingly distinct areas of cancer, development and pluripotency. Protein complexes participating in DNA replication origin licensing are now known to have roles in development, while their deregulation can lead to cancer. Moreover, transcription factors implicated in the maintenance of or reversal to the pluripotent state have links to the pre-replicative machinery. Several studies have shown that overexpression of these factors is associated to cancer.
Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

Entities:  

Keywords:  Cancer; DNA replication; Development; Licensing; Origin specification; Pluripotency

Mesh：

Year:  2014        PMID： 24641889     DOI： 10.1016/j.semcdb.2014.03.013

Source DB:  PubMed          Journal:  Semin Cell Dev Biol        ISSN： 1084-9521            Impact factor:   7.727


  28 in total

1.  Carcinogenic Pesticide Control via Hijacking Endosymbiosis; The Paradigm of DSB-A from Wolbachia pipientis for the Management of Otiorhynchus singularis.

Authors:  Thomas Kostaropoulos; Louis Papageorgiou; Spyridon Champeris Tsaniras; Dimitrios Vlachakis; Elias Eliopoulos
Journal:  In Vivo       Date:  2018 Sep-Oct       Impact factor: 2.155

2.  Mcidas and GemC1/Lynkeas specify embryonic radial glial cells.

Authors:  Christina Kyrousi; Maria-Eleni Lalioti; Eleni Skavatsou; Zoi Lygerou; Stavros Taraviras
Journal:  Neurogenesis (Austin)       Date:  2016-04-27

3.  ILK Expression in Colorectal Cancer Is Associated with EMT, Cancer Stem Cell Markers and Chemoresistance.

Authors:  Dimitrios Tsoumas; Sofia Nikou; Efstathia Giannopoulou; Spyridon Champeris Tsaniras; Chaido Sirinian; Ioannis Maroulis; Stavros Taraviras; Vassiliki Zolota; Haralabos P Kalofonos; Vasiliki Bravou
Journal:  Cancer Genomics Proteomics       Date:  2018 Mar-Apr       Impact factor: 4.069

4.  In silico analysis of DNA re-replication across a complete genome reveals cell-to-cell heterogeneity and genome plasticity.

Authors:  Maria Anna Rapsomaniki; Stella Maxouri; Patroula Nathanailidou; Manuel Ramirez Garrastacho; Nickolaos Nikiforos Giakoumakis; Stavros Taraviras; John Lygeros; Zoi Lygerou
Journal:  NAR Genom Bioinform       Date:  2021-01-28

5.  The overexpression of KIFC1 was associated with the proliferation and prognosis of non-small cell lung cancer.

Authors:  Yafang Liu; Ping Zhan; Zejun Zhou; Ze Xing; Suhua Zhu; Chenhui Ma; Qian Li; Qingqing Zhu; Yingying Miao; Jianya Zhang; Tangfeng Lv; Yong Song
Journal:  J Thorac Dis       Date:  2016-10       Impact factor: 2.895

6.  DNA Replication Inhibitor Geminin and Retinoic Acid Signaling Participate in Complex Interactions Associated With Pluripotency.

Authors:  Spyridon Champeris Tsaniras; George J Delinasios; Michalis Petropoulos; Andreas Panagopoulos; Athanasios K Anagnostopoulos; Maria Villiou; Dimitrios Vlachakis; Vasiliki Bravou; Georgios T Stathopoulos; Stavros Taraviras
Journal:  Cancer Genomics Proteomics       Date:  2019 Nov-Dec       Impact factor: 4.069

7.  GemC1 controls multiciliogenesis in the airway epithelium.

Authors:  Marina Arbi; Dafni-Eleftheria Pefani; Christina Kyrousi; Maria-Eleni Lalioti; Argyro Kalogeropoulou; Anastasios D Papanastasiou; Stavros Taraviras; Zoi Lygerou
Journal:  EMBO Rep       Date:  2016-02-04       Impact factor: 8.807

8.  Myricetin inhibits proliferation of cisplatin-resistant cancer cells through a p53-dependent apoptotic pathway.

Authors:  Haizhi Huang; Allen Y Chen; Xingqian Ye; Bingyun Li; Yon Rojanasakul; Gary O Rankin; Yi Charlie Chen
Journal:  Int J Oncol       Date:  2015-08-25       Impact factor: 5.650

9.  The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins.

Authors:  Christophe Caillat; Alexander Fish; Dafni Eleftheria Pefani; Stavros Taraviras; Zoi Lygerou; Anastassis Perrakis
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2015-10-31

10.  Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality.

Authors:  Silvia Alvarez; Marcos Díaz; Johanna Flach; Sara Rodriguez-Acebes; Andrés J López-Contreras; Dolores Martínez; Marta Cañamero; Oscar Fernández-Capetillo; Joan Isern; Emmanuelle Passegué; Juan Méndez
Journal:  Nat Commun       Date:  2015-10-12       Impact factor: 14.919
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