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Literature DB >> 24622198

The present and future role of microfluidics in biomedical research.

Eric K Sackmann¹, Anna L Fulton², David J Beebe³.

Abstract

Microfluidics, a technology characterized by the engineered manipulation of fluids at the submillimetre scale, has shown considerable promise for improving diagnostics and biology research. Certain properties of microfluidic technologies, such as rapid sample processing and the precise control of fluids in an assay, have made them attractive candidates to replace traditional experimental approaches. Here we analyse the progress made by lab-on-a-chip microtechnologies in recent years, and discuss the clinical and research areas in which they have made the greatest impact. We also suggest directions that biologists, engineers and clinicians can take to help this technology live up to its potential.

Mesh：

Year: 2014 PMID： 24622198 DOI： 10.1038/nature13118

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

85 in total

1. Understanding wax printing: a simple micropatterning process for paper-based microfluidics.

Authors: Emanuel Carrilho; Andres W Martinez; George M Whitesides
Journal: Anal Chem Date: 2009-08-15 Impact factor: 6.986

Review 2. Crossing the endothelial barrier during metastasis.

Authors: Nicolas Reymond; Bárbara Borda d'Água; Anne J Ridley
Journal: Nat Rev Cancer Date: 2013-12 Impact factor: 60.716

Review 3. Managing evaporation for more robust microscale assays. Part 1. Volume loss in high throughput assays.

Authors: Erwin Berthier; Jay Warrick; Hongmeiy Yu; David J Beebe
Journal: Lab Chip Date: 2008-04-08 Impact factor: 6.799

4. An integrated microfluidic system for long-term perfusion culture and on-line monitoring of intestinal tissue models.

Authors: Hiroshi Kimura; Takatoki Yamamoto; Hitomi Sakai; Yasuyuki Sakai; Teruo Fujii
Journal: Lab Chip Date: 2008-04-04 Impact factor: 6.799

5. Hype, hope and hubris: the quest for the killer application in microfluidics.

Authors: Holger Becker
Journal: Lab Chip Date: 2009-06-23 Impact factor: 6.799

6. Cool, or simple and cheap? Why not both?

Authors: George M Whitesides
Journal: Lab Chip Date: 2012-11-19 Impact factor: 6.799

7. Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane).

Authors: D C Duffy; J C McDonald; O J Schueller; G M Whitesides
Journal: Anal Chem Date: 1998-12-01 Impact factor: 6.986

8. Surface modification of poly(methyl methacrylate) used in the fabrication of microanalytical devices.

Authors: A C Henry; T J Tutt; M Galloway; Y Y Davidson; C S McWhorter; S A Soper; R L McCarley
Journal: Anal Chem Date: 2000-11-01 Impact factor: 6.986

Review 9. Microfluidics meet cell biology: bridging the gap by validation and application of microscale techniques for cell biological assays.

Authors: Amy L Paguirigan; David J Beebe
Journal: Bioessays Date: 2008-09 Impact factor: 4.345

10. An improved chamber for direct visualisation of chemotaxis.

Authors: Andrew J Muinonen-Martin; Douwe M Veltman; Gabriela Kalna; Robert H Insall
Journal: PLoS One Date: 2010-12-14 Impact factor: 3.240

509 in total

Review 1. Live from under the lens: exploring microbial motility with dynamic imaging and microfluidics.

Authors: Kwangmin Son; Douglas R Brumley; Roman Stocker
Journal: Nat Rev Microbiol Date: 2015-12 Impact factor: 60.633

2. A spatiotemporally controllable chemical gradient generator via acoustically oscillating sharp-edge structures.

Authors: Po-Hsun Huang; Chung Yu Chan; Peng Li; Nitesh Nama; Yuliang Xie; Cheng-Hsin Wei; Yuchao Chen; Daniel Ahmed; Tony Jun Huang
Journal: Lab Chip Date: 2015-09-04 Impact factor: 6.799

3. Enhanced H-filter based on Fåhræus-Lindqvist effect for efficient and robust dialysis without membrane.

Authors: Wei-Chao Zheng; Rui Xie; Li-Qun He; Yue-Heng Xi; Ying-Mei Liu; Zhi-Jun Meng; Wei Wang; Xiao-Jie Ju; Gang Chen; Liang-Yin Chu
Journal: Biomicrofluidics Date: 2015-07-31 Impact factor: 2.800

4. Lab-on-Chip-Based Platform for Fast Molecular Diagnosis of Multidrug-Resistant Tuberculosis.

Authors: Andrea M Cabibbe; Paolo Miotto; Raquel Moure; Fernando Alcaide; Silke Feuerriegel; Gianni Pozzi; Vladislav Nikolayevskyy; Francis Drobniewski; Stefan Niemann; Klaus Reither; Daniela M Cirillo
Journal: J Clin Microbiol Date: 2015-08-05 Impact factor: 5.948

5. Hydrodynamic self-focusing in a parallel microfluidic device through cross-filtration.

Authors: S Torino; M Iodice; I Rendina; G Coppola; E Schonbrun
Journal: Biomicrofluidics Date: 2015-11-20 Impact factor: 2.800

6. Lab-on-a-chip workshop activities for secondary school students.

Authors: Mohammad M N Esfahani; Mark D Tarn; Tahmina A Choudhury; Laura C Hewitt; Ashley J Mayo; Theodore A Rubin; Mathew R Waller; Martin G Christensen; Amy Dawson; Nicole Pamme
Journal: Biomicrofluidics Date: 2016-02-02 Impact factor: 2.800

7. Soft lithography fabrication of index-matched microfluidic devices for reducing artifacts in fluorescence and quantitative phase imaging.

Authors: Diane N H Kim; Kevin T Kim; Carolyn Kim; Michael A Teitell; Thomas A Zangle
Journal: Microfluid Nanofluidics Date: 2017-12-01 Impact factor: 2.529