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Literature DB >> 24615922

Microfluidic-based generation of size-controlled, biofunctionalized synthetic polymer microgels for cell encapsulation.

Devon M Headen¹, Guillaume Aubry, Hang Lu, Andrés J García.

Abstract

Cell and islet microencapsulation in synthetic hydrogels provides an immunoprotective and cell-supportive microenvironment. A microfluidic strategy for the genaration of biofunctionalized, synthetic microgel particles with precise control over particle size and molecular permeability for cell and protein delivery is presented. These engineered capsules support high cell viability and function of encapsulated human stem cells and islets.

Entities: Chemical Disease Gene Species

Keywords: cell microencapsulation; hydrogels; microfluidics; pancreatic islets; synthetic microgel

Mesh：

Substances：

Year: 2014 PMID： 24615922 PMCID： PMC4058833 DOI： 10.1002/adma.201304880

Source DB: PubMed Journal: Adv Mater ISSN： 0935-9648 Impact factor: 30.849

25 in total

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45 in total

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Authors: James R Day; Anu David; Alexa L Cichon; Tanay Kulkarni; Marilia Cascalho; Ariella Shikanov
Journal: J Biomed Mater Res A Date: 2018-02-05 Impact factor: 4.396

2. Articular Cartilage- and Synoviocyte-Binding Poly(ethylene glycol) Nanocomposite Microgels as Intra-Articular Drug Delivery Vehicles for the Treatment of Osteoarthritis.

Authors: Lina M Mancipe Castro; Abigail Sequeira; Andrés J García; Robert E Guldberg
Journal: ACS Biomater Sci Eng Date: 2020-08-28

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