Literature DB >> 22467645

Microfluidic encapsulation of cells in polymer microgels.

Diego Velasco1, Ethan Tumarkin, Eugenia Kumacheva.   

Abstract

In this Concept article, recent advances in microfluidic platforms for the generation of cell-laden hydrogel particles (microgels) are reported. Advances in the continuous microfluidic encapsulation of cells in droplets and microgels are critically reviewed, and currently used methods for the encapsulation of cells in polymer microgels are discussed. An outlook on current applications and future directions in this field of research are also presented. This article will be of interest to chemists, materials scientists, cell biologists, bioengineers, and pharmacologists.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2012        PMID: 22467645     DOI: 10.1002/smll.201102464

Source DB:  PubMed          Journal:  Small        ISSN: 1613-6810            Impact factor:   13.281


  41 in total

Review 1.  Concise review: microfluidic technology platforms: poised to accelerate development and translation of stem cell-derived therapies.

Authors:  Drew M Titmarsh; Huaying Chen; Nick R Glass; Justin J Cooper-White
Journal:  Stem Cells Transl Med       Date:  2013-12-05       Impact factor: 6.940

2.  Single cell-laden protease-sensitive microniches for long-term culture in 3D.

Authors:  Philipp S Lienemann; Torsten Rossow; Angelo S Mao; Queralt Vallmajo-Martin; Martin Ehrbar; David J Mooney
Journal:  Lab Chip       Date:  2017-02-14       Impact factor: 6.799

Review 3.  Concise review: tailoring bioengineered scaffolds for stem cell applications in tissue engineering and regenerative medicine.

Authors:  Steffen Cosson; Ellen A Otte; Hadi Hezaveh; Justin J Cooper-White
Journal:  Stem Cells Transl Med       Date:  2015-01-09       Impact factor: 6.940

4.  An acoustofluidic platform for non-contact trapping of cell-laden hydrogel droplets compatible with optical microscopy.

Authors:  Anna Fornell; Carl Johannesson; Sean S Searle; Axel Happstadius; Johan Nilsson; Maria Tenje
Journal:  Biomicrofluidics       Date:  2019-07-11       Impact factor: 2.800

Review 5.  Advances in multicellular spheroids formation.

Authors:  X Cui; Y Hartanto; H Zhang
Journal:  J R Soc Interface       Date:  2017-02       Impact factor: 4.118

6.  Microfluidic Generation of Monodisperse, Structurally Homogeneous Alginate Microgels for Cell Encapsulation and 3D Cell Culture.

Authors:  Stefanie Utech; Radivoje Prodanovic; Angelo S Mao; Raluca Ostafe; David J Mooney; David A Weitz
Journal:  Adv Healthc Mater       Date:  2015-06-03       Impact factor: 9.933

7.  Comparative cytocompatibility of multiple candidate cell types to photoencapsulation in PEGNB/PEGDA macroscale or microscale hydrogels.

Authors:  Zhongliang Jiang; Kun Jiang; Ralph McBride; John S Oakey
Journal:  Biomed Mater       Date:  2018-10-02       Impact factor: 3.715

8.  A microfluidic-based cell encapsulation platform to achieve high long-term cell viability in photopolymerized PEGNB hydrogel microspheres.

Authors:  Zhongliang Jiang; Bingzhao Xia; Ralph McBride; John Oakey
Journal:  J Mater Chem B       Date:  2016-11-25       Impact factor: 6.331

9.  One-step microfluidic generation of pre-hatching embryo-like core-shell microcapsules for miniaturized 3D culture of pluripotent stem cells.

Authors:  Pranay Agarwal; Shuting Zhao; Peter Bielecki; Wei Rao; Jung Kyu Choi; Yi Zhao; Jianhua Yu; Wujie Zhang; Xiaoming He
Journal:  Lab Chip       Date:  2013-12-07       Impact factor: 6.799

Review 10.  Cell armor for protection against environmental stress: Advances, challenges and applications in micro- and nanoencapsulation of mammalian cells.

Authors:  Onur Hasturk; David L Kaplan
Journal:  Acta Biomater       Date:  2018-11-24       Impact factor: 8.947

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