Chi-Min Park1, Younsuck Koh2, Kyeongman Jeon3, Sungwon Na4, Chae-Man Lim2, Won-Il Choi5, Young-Joo Lee6, Seok Chan Kim7, Gyu Rak Chon8, Je Hyeong Kim9, Jae Yeol Kim10, Jaemin Lim11, Chin Kook Rhee7, Sunghoon Park12, Ho Cheol Kim13, Jin Hwa Lee14, Ji Hyun Lee15, Jisook Park16, Juhee Cho17, Shin Ok Koh4, Gee Young Suh18. 1. Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. 2. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. 3. Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. 4. Department of Anesthesiology and Pain Medicine, and Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea. 5. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Keimyung University, Dongsan Hospital, Seoul, Korea. 6. Department of Anesthesiology and Pain Medicine, Ewha Womans University, Mokdong Hospital, Seoul, Korea. 7. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Seoul St Mary's Hospital, Catholic University of Korea, Seoul, Korea. 8. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Chungju Hospital, School of Medicine of Konkuk University, Chungju, Korea. 9. Division of Pulmonary, Sleep and Critical Care Medicine, Department of Medicine, Korea University Ansan Hospital, Ansan, Korea. 10. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Chung-Ang University College of Medicine, Ansan, Korea. 11. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Gangneung Asan Hospital, University of Ulsan Medical College of Medicine, Gangneung, Korea. 12. Department of Pulmonary, Allergy and Critical Care Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea. 13. Division of Pulmonary and Critical Care Medicine, Department of Medicine, College of Medicine, Gyeongsang Institute of Health Sciences, Gyeongsang National University, Jinju, Korea. 14. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Ewha Womans University School of Medicine, Seoul, Korea. 15. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Bundang CHA Hospital CHA University, Seongnam, Korea. 16. Department of Multimedia, Seoul Women's University, Seoul, Korea. 17. Department of Health Science and Technology, SAIHST, Sungkyunkwan University, Seoul, Korea; Department of Epidemiology and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA. 18. Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. Electronic address: suhgy@skku.edu.
Abstract
INTRODUCTION: This study evaluates the association between the Eastern Cooperative Oncology Group Performance Status (ECOG-PS) and hospital mortality in general critically ill patients. MATERIALS AND METHODS: This is a retrospective cohort study that analyzes prospective collected data from the Validation of Simplified acute physiology score 3 in Korean Intensive care unit study. The study population comprised patients who were consecutively admitted to participating intensive care units from July 1, 2010, to January 31, 2011. Univariate and multivariate logistic regression models were used to evaluate the effect of ECOG-PS on hospital mortality. RESULTS: A total of 3868 patients were included in the analysis. There was a significant trend for increasing hospital mortality as the ECOG-PS grade became higher (P<.001). There was a trend of increasing adjusted odds ratio for hospital mortality, with grade 1 of PS 1.4 (95% confidence intervals [CIs], 1.0-1.8), grade 2 of PS 2.0 (95% CIs, 1.5-2.7), grade 3 of PS 2.9 (95% CIs, 2.1-4.1), and grade 4 of PS 2.5 (95% CIs, 1.6-3.9). Also, there was a significant difference in all grades. Subgroup analysis showed a trend of increasing hospital mortality regardless of the presence of cancer. CONCLUSION: Preadmission PS, assessed with ECOG-PS in critically ill patients, has prognostic value in general critically ill patients.
INTRODUCTION: This study evaluates the association between the Eastern Cooperative Oncology Group Performance Status (ECOG-PS) and hospital mortality in general critically ill patients. MATERIALS AND METHODS: This is a retrospective cohort study that analyzes prospective collected data from the Validation of Simplified acute physiology score 3 in Korean Intensive care unit study. The study population comprised patients who were consecutively admitted to participating intensive care units from July 1, 2010, to January 31, 2011. Univariate and multivariate logistic regression models were used to evaluate the effect of ECOG-PS on hospital mortality. RESULTS: A total of 3868 patients were included in the analysis. There was a significant trend for increasing hospital mortality as the ECOG-PS grade became higher (P<.001). There was a trend of increasing adjusted odds ratio for hospital mortality, with grade 1 of PS 1.4 (95% confidence intervals [CIs], 1.0-1.8), grade 2 of PS 2.0 (95% CIs, 1.5-2.7), grade 3 of PS 2.9 (95% CIs, 2.1-4.1), and grade 4 of PS 2.5 (95% CIs, 1.6-3.9). Also, there was a significant difference in all grades. Subgroup analysis showed a trend of increasing hospital mortality regardless of the presence of cancer. CONCLUSION: Preadmission PS, assessed with ECOG-PS in critically ill patients, has prognostic value in general critically ill patients.
Authors: Fernando G Zampieri; Fernando A Bozza; Giulliana M Moralez; Débora D S Mazza; Alexandre V Scotti; Marcelo S Santino; Rubens A B Ribeiro; Edison M Rodrigues Filho; Maurício M Cabral; Marcelo O Maia; Patrícia S D'Alessandro; Sandro V Oliveira; Márcia A M Menezes; Eliana B Caser; Roberto S Lannes; Meton S Alencar Neto; Maristela M Machado; Marcelo F Sousa; Jorge I F Salluh; Marcio Soares Journal: Intensive Care Med Date: 2016-09-29 Impact factor: 17.440
Authors: Seok Reyol Choi; Sam Ryong Jee; Geun Am Song; Seun Ja Park; Jong Hun Lee; Chul Soo Song; Hee Ug Park Journal: Gut Liver Date: 2015-11-23 Impact factor: 4.519