Literature DB >> 24598546

Neurodegenerative diseases: G-quadruplex poses quadruple threat.

J Paul Taylor1.   

Abstract

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Year:  2014        PMID： 24598546     DOI： 10.1038/nature13067

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  19 in total

1.  Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS.

Authors:  Mariely DeJesus-Hernandez; Ian R Mackenzie; Bradley F Boeve; Adam L Boxer; Matt Baker; Nicola J Rutherford; Alexandra M Nicholson; NiCole A Finch; Heather Flynn; Jennifer Adamson; Naomi Kouri; Aleksandra Wojtas; Pheth Sengdy; Ging-Yuek R Hsiung; Anna Karydas; William W Seeley; Keith A Josephs; Giovanni Coppola; Daniel H Geschwind; Zbigniew K Wszolek; Howard Feldman; David S Knopman; Ronald C Petersen; Bruce L Miller; Dennis W Dickson; Kevin B Boylan; Neill R Graff-Radford; Rosa Rademakers
Journal:  Neuron       Date:  2011-09-21       Impact factor: 17.173

2.  Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration.

Authors:  Clotilde Lagier-Tourenne; Michael Baughn; Frank Rigo; Shuying Sun; Patrick Liu; Hai-Ri Li; Jie Jiang; Andrew T Watt; Seung Chun; Melanie Katz; Jinsong Qiu; Ying Sun; Shuo-Chien Ling; Qiang Zhu; Magdalini Polymenidou; Kevin Drenner; Jonathan W Artates; Melissa McAlonis-Downes; Sebastian Markmiller; Kasey R Hutt; Donald P Pizzo; Janet Cady; Matthew B Harms; Robert H Baloh; Scott R Vandenberg; Gene W Yeo; Xiang-Dong Fu; C Frank Bennett; Don W Cleveland; John Ravits
Journal:  Proc Natl Acad Sci U S A       Date:  2013-10-29       Impact factor: 11.205

3.  The disease-associated r(GGGGCC)n repeat from the C9orf72 gene forms tract length-dependent uni- and multimolecular RNA G-quadruplex structures.

Authors:  Kaalak Reddy; Bita Zamiri; Sabrina Y R Stanley; Robert B Macgregor; Christopher E Pearson
Journal:  J Biol Chem       Date:  2013-02-19       Impact factor: 5.157

Review 4.  DNA secondary structures: stability and function of G-quadruplex structures.

Authors:  Matthew L Bochman; Katrin Paeschke; Virginia A Zakian
Journal:  Nat Rev Genet       Date:  2012-10-03       Impact factor: 53.242

5.  Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration.

Authors:  Zihui Xu; Mickael Poidevin; Xuekun Li; Yujing Li; Liqi Shu; David L Nelson; He Li; Chadwick M Hales; Marla Gearing; Thomas S Wingo; Peng Jin
Journal:  Proc Natl Acad Sci U S A       Date:  2013-04-03       Impact factor: 11.205

6.  Hypermethylation of the CpG island near the G4C2 repeat in ALS with a C9orf72 expansion.

Authors:  Zhengrui Xi; Lorne Zinman; Danielle Moreno; Jennifer Schymick; Yan Liang; Christine Sato; Yonglan Zheng; Mahdi Ghani; Samar Dib; Julia Keith; Janice Robertson; Ekaterina Rogaeva
Journal:  Am J Hum Genet       Date:  2013-05-23       Impact factor: 11.025

7.  RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention.

Authors:  Christopher J Donnelly; Ping-Wu Zhang; Jacqueline T Pham; Aaron R Haeusler; Aaron R Heusler; Nipun A Mistry; Svetlana Vidensky; Elizabeth L Daley; Erin M Poth; Benjamin Hoover; Daniel M Fines; Nicholas Maragakis; Pentti J Tienari; Leonard Petrucelli; Bryan J Traynor; Jiou Wang; Frank Rigo; C Frank Bennett; Seth Blackshaw; Rita Sattler; Jeffrey D Rothstein
Journal:  Neuron       Date:  2013-10-16       Impact factor: 17.173

8.  C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes.

Authors:  Pietro Fratta; Sarah Mizielinska; Andrew J Nicoll; Mire Zloh; Elizabeth M C Fisher; Gary Parkinson; Adrian M Isaacs
Journal:  Sci Rep       Date:  2012-12-21       Impact factor: 4.379

9.  Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic.

Authors:  Youn-Bok Lee; Han-Jou Chen; João N Peres; Jorge Gomez-Deza; Jan Attig; Maja Stalekar; Claire Troakes; Agnes L Nishimura; Emma L Scotter; Caroline Vance; Yoshitsugu Adachi; Valentina Sardone; Jack W Miller; Bradley N Smith; Jean-Marc Gallo; Jernej Ule; Frank Hirth; Boris Rogelj; Corinne Houart; Christopher E Shaw
Journal:  Cell Rep       Date:  2013-11-27       Impact factor: 9.423

10.  C9orf72 nucleotide repeat structures initiate molecular cascades of disease.

Authors:  Aaron R Haeusler; Christopher J Donnelly; Goran Periz; Eric A J Simko; Patrick G Shaw; Min-Sik Kim; Nicholas J Maragakis; Juan C Troncoso; Akhilesh Pandey; Rita Sattler; Jeffrey D Rothstein; Jiou Wang
Journal:  Nature       Date:  2014-03-05       Impact factor: 49.962
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  17 in total

1.  The Hairpin Form of r(G4C2)exp in c9ALS/FTD Is Repeat-Associated Non-ATG Translated and a Target for Bioactive Small Molecules.

Authors:  Zi-Fu Wang; Andrei Ursu; Jessica L Childs-Disney; Rea Guertler; Wang-Yong Yang; Viachaslau Bernat; Suzanne G Rzuczek; Rita Fuerst; Yong-Jie Zhang; Tania F Gendron; Ilyas Yildirim; Brendan G Dwyer; Joseph E Rice; Leonard Petrucelli; Matthew D Disney
Journal:  Cell Chem Biol       Date:  2018-11-29       Impact factor: 8.116

Review 2.  Methods to identify and optimize small molecules interacting with RNA (SMIRNAs).

Authors:  Andrei Ursu; Simon Vézina-Dawod; Matthew D Disney
Journal:  Drug Discov Today       Date:  2019-07-26       Impact factor: 7.851

Review 3.  Decoding ALS: from genes to mechanism.

Authors:  J Paul Taylor; Robert H Brown; Don W Cleveland
Journal:  Nature       Date:  2016-11-10       Impact factor: 49.962

4.  Studying the Dynamics of a Complex G-Quadruplex System: Insights into the Comparison of MD and NMR Data.

Authors:  Matteo Castelli; Filippo Doria; Mauro Freccero; Giorgio Colombo; Elisabetta Moroni
Journal:  J Chem Theory Comput       Date:  2022-06-06       Impact factor: 6.578

5.  Defining the sequence requirements for the positioning of base J in DNA using SMRT sequencing.

Authors:  Paul-Andre Genest; Loren Baugh; Alex Taipale; Wanqi Zhao; Sabrina Jan; Henri G A M van Luenen; Jonas Korlach; Tyson Clark; Khai Luong; Matthew Boitano; Steve Turner; Peter J Myler; Piet Borst
Journal:  Nucleic Acids Res       Date:  2015-02-06       Impact factor: 16.971

6.  Nucleolin stabilizes G-quadruplex structures folded by the LTR promoter and silences HIV-1 viral transcription.

Authors:  Elena Tosoni; Ilaria Frasson; Matteo Scalabrin; Rosalba Perrone; Elena Butovskaya; Matteo Nadai; Giorgio Palù; Dan Fabris; Sara N Richter
Journal:  Nucleic Acids Res       Date:  2015-09-09       Impact factor: 16.971

7.  Synthesis, Binding and Antiviral Properties of Potent Core-Extended Naphthalene Diimides Targeting the HIV-1 Long Terminal Repeat Promoter G-Quadruplexes.

Authors:  Rosalba Perrone; Filippo Doria; Elena Butovskaya; Ilaria Frasson; Silvia Botti; Matteo Scalabrin; Sara Lago; Vincenzo Grande; Matteo Nadai; Mauro Freccero; Sara N Richter
Journal:  J Med Chem       Date:  2015-12-08       Impact factor: 7.446

8.  G-quadruplex structures formed by expanded hexanucleotide repeat RNA and DNA from the neurodegenerative disease-linked C9orf72 gene efficiently sequester and activate heme.

Authors:  Jason C Grigg; Nisreen Shumayrikh; Dipankar Sen
Journal:  PLoS One       Date:  2014-09-10       Impact factor: 3.240

9.  Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress.

Authors:  Yong-Jie Zhang; Karen Jansen-West; Ya-Fei Xu; Tania F Gendron; Kevin F Bieniek; Wen-Lang Lin; Hiroki Sasaguri; Thomas Caulfield; Jaime Hubbard; Lillian Daughrity; Jeannie Chew; Veronique V Belzil; Mercedes Prudencio; Jeannette N Stankowski; Monica Castanedes-Casey; Ena Whitelaw; Peter E A Ash; Michael DeTure; Rosa Rademakers; Kevin B Boylan; Dennis W Dickson; Leonard Petrucelli
Journal:  Acta Neuropathol       Date:  2014-08-31       Impact factor: 17.088

10.  Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genome.

Authors:  Beatrice De Nicola; Christopher J Lech; Brahim Heddi; Sagar Regmi; Ilaria Frasson; Rosalba Perrone; Sara N Richter; Anh Tuân Phan
Journal:  Nucleic Acids Res       Date:  2016-06-13       Impact factor: 16.971
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