Literature DB >> 24569671

Dereplication of microbial extracts and related analytical technologies.

Tatsuya Ito1, Miyako Masubuchi1.   

Abstract

Natural products still continue to have an important role as a resource of various biologically active substances. Dereplication is a key process in natural product screening that analyzes the extracts of microbial fermentation broths or plant samples. In this review article, we describe and discuss the analytical techniques of dereplication and related technologies in the following sections: 1. Direct detection from microbial colonies. 2. Ultra high performance liquid chromatography (UHPLC)-MS profiling for library construction. 3. Micro-fractionation to identify active peaks. 4. Quantification of small-amount compounds. 5. Structure identification from small amounts. Using these techniques, the desired compound in the mixture library can be rapidly identified.

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Year:  2014        PMID： 24569671     DOI： 10.1038/ja.2014.12

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  23 in total

1.  Evaporative light scattering quantification of natural products possessing a carbon-phosphorus bond.

Authors:  Matthew C Chi; Geoff P Horsman
Journal:  J Antibiot (Tokyo)       Date:  2015-05-20       Impact factor: 2.649

2.  Identification of new geldanamycin derivatives from unexplored microbial culture extracts using a MS/MS library.

Authors:  Jae Kyoung Lee; Jae-Hyuk Jang; Dong-Jin Park; Chang-Jin Kim; Jong Seog Ahn; Bang Yeon Hwang; Young-Soo Hong
Journal:  J Antibiot (Tokyo)       Date:  2016-12-21       Impact factor: 2.649

Review 3.  Current status and contemporary approaches to the discovery of antitumor agents from higher plants.

Authors:  Garima Agarwal; Peter J Blanco Carcache; Ermias Mekuria Addo; A Douglas Kinghorn
Journal:  Biotechnol Adv       Date:  2019-01-08       Impact factor: 14.227

Review 4.  Droplet probe: coupling chromatography to the in situ evaluation of the chemistry of nature.

Authors:  Nicholas H Oberlies; Sonja L Knowles; Chiraz Soumia M Amrine; Diana Kao; Vilmos Kertesz; Huzefa A Raja
Journal:  Nat Prod Rep       Date:  2019-05-21       Impact factor: 13.423

5.  Activity-Independent Discovery of Secondary Metabolites Using Chemical Elicitation and Cheminformatic Inference.

Authors:  Sheila M Pimentel-Elardo; Dan Sørensen; Louis Ho; Mikaela Ziko; Stephanie A Bueler; Stella Lu; Joe Tao; Arvin Moser; Richard Lee; David Agard; Greg Fairn; John L Rubinstein; Brian K Shoichet; Justin R Nodwell
Journal:  ACS Chem Biol       Date:  2015-09-18       Impact factor: 5.100

6.  Biosynthetically Distinct Cytotoxic Polyketides from Setophoma terrestris.

Authors:  Tamam El-Elimat; Mario Figueroa; Huzefa A Raja; Tyler N Graf; Steven M Swanson; Joseph O Falkinham; Mansukh C Wani; Cedric J Pearce; Nicholas H Oberlies
Journal:  European J Org Chem       Date:  2015-01-01

7.  Phylogenetic Relationship and Secondary Metabolite Production of Marine Fungi Producing the Cyclodepsipeptides Scopularide A and B.

Authors:  Annemarie Kramer; Antje Labes; Johannes F Imhoff
Journal:  Mar Biotechnol (NY)       Date:  2016-05-21       Impact factor: 3.619

8.  Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking.

Authors:  Mingxun Wang; Jeremy J Carver; Vanessa V Phelan; Laura M Sanchez; Neha Garg; Yao Peng; Don Duy Nguyen; Jeramie Watrous; Clifford A Kapono; Tal Luzzatto-Knaan; Carla Porto; Amina Bouslimani; Alexey V Melnik; Michael J Meehan; Wei-Ting Liu; Max Crüsemann; Paul D Boudreau; Eduardo Esquenazi; Mario Sandoval-Calderón; Roland D Kersten; Laura A Pace; Robert A Quinn; Katherine R Duncan; Cheng-Chih Hsu; Dimitrios J Floros; Ronnie G Gavilan; Karin Kleigrewe; Trent Northen; Rachel J Dutton; Delphine Parrot; Erin E Carlson; Bertrand Aigle; Charlotte F Michelsen; Lars Jelsbak; Christian Sohlenkamp; Pavel Pevzner; Anna Edlund; Jeffrey McLean; Jörn Piel; Brian T Murphy; Lena Gerwick; Chih-Chuang Liaw; Yu-Liang Yang; Hans-Ulrich Humpf; Maria Maansson; Robert A Keyzers; Amy C Sims; Andrew R Johnson; Ashley M Sidebottom; Brian E Sedio; Andreas Klitgaard; Charles B Larson; Cristopher A Boya P; Daniel Torres-Mendoza; David J Gonzalez; Denise B Silva; Lucas M Marques; Daniel P Demarque; Egle Pociute; Ellis C O'Neill; Enora Briand; Eric J N Helfrich; Eve A Granatosky; Evgenia Glukhov; Florian Ryffel; Hailey Houson; Hosein Mohimani; Jenan J Kharbush; Yi Zeng; Julia A Vorholt; Kenji L Kurita; Pep Charusanti; Kerry L McPhail; Kristian Fog Nielsen; Lisa Vuong; Maryam Elfeki; Matthew F Traxler; Niclas Engene; Nobuhiro Koyama; Oliver B Vining; Ralph Baric; Ricardo R Silva; Samantha J Mascuch; Sophie Tomasi; Stefan Jenkins; Venkat Macherla; Thomas Hoffman; Vinayak Agarwal; Philip G Williams; Jingqui Dai; Ram Neupane; Joshua Gurr; Andrés M C Rodríguez; Anne Lamsa; Chen Zhang; Kathleen Dorrestein; Brendan M Duggan; Jehad Almaliti; Pierre-Marie Allard; Prasad Phapale; Louis-Felix Nothias; Theodore Alexandrov; Marc Litaudon; Jean-Luc Wolfender; Jennifer E Kyle; Thomas O Metz; Tyler Peryea; Dac-Trung Nguyen; Danielle VanLeer; Paul Shinn; Ajit Jadhav; Rolf Müller; Katrina M Waters; Wenyuan Shi; Xueting Liu; Lixin Zhang; Rob Knight; Paul R Jensen; Bernhard O Palsson; Kit Pogliano; Roger G Linington; Marcelino Gutiérrez; Norberto P Lopes; William H Gerwick; Bradley S Moore; Pieter C Dorrestein; Nuno Bandeira
Journal:  Nat Biotechnol       Date:  2016-08-09       Impact factor: 54.908

9.  Variation Among Biosynthetic Gene Clusters, Secondary Metabolite Profiles, and Cards of Virulence Across Aspergillus Species.

Authors:  Matthew E Mead; Sonja L Knowles; Jacob L Steenwyk; Huzefa A Raja; Christopher D Roberts; Oliver Bader; Jos Houbraken; Gustavo H Goldman; Nicholas H Oberlies; Antonis Rokas
Journal:  Genetics       Date:  2020-08-17       Impact factor: 4.562

Review 10.  Dereplication, sequencing and identification of peptidic natural products: from genome mining to peptidogenomics to spectral networks.

Authors:  Hosein Mohimani; Pavel A Pevzner
Journal:  Nat Prod Rep       Date:  2016-01       Impact factor: 13.423
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