| Literature DB >> 24532384 |
Nikola Basarić1, Margareta Sohora, Nikola Cindro, Kata Mlinarić-Majerski, Erik De Clercq, Jan Balzarini.
Abstract
Three libraries of adamantane derivatives were synthesized and evaluated for antiviral and antiproliferative activities against a broad variety of DNA and RNA viruses. Whereas none of the compounds exhibit antiviral activity at subtoxic concentrations, antiproliferative activity was found against murine leukemia cells (L1210), human T-lymphocyte cells (CEM), and cervix carcinoma cells (HeLa) for 4, 8, and 10.Entities:
Keywords: Adamantanes; Antiproliferative activity; Antiviral activity; Phthalimides; Polycyclic compounds; Unnatural amino acids
Mesh：
Substances：
Year: 2014 PMID： 24532384 DOI： 10.1002/ardp.201300345
Source DB: PubMed Journal: Arch Pharm (Weinheim) ISSN： 0365-6233 Impact factor: 3.751