Ivonne Sluijs1, Sebastien Czernichow, Joline W J Beulens, Jolanda M A Boer, Yvonne T van der Schouw, W Monique M Verschuren, Diederick E Grobbee. 1. From the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands (I.S., J.W.J.B., Y.T.v.d.S., D.E.G.); Department of Nutrition, Assistance Publique-Hôpitaux de Paris, Hôpital A Paré, Université Versailles St-Quentin, Boulogne, France (S.C.); INSERM U1018, Centre for Research in Epidemiology and Population Health, Villejuif, France (S.C.); and Centre for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands (J.M.A.B., W.M.M.V.).
Abstract
BACKGROUND AND PURPOSE: We aimed to investigate the associations of dietary and total potassium, magnesium, and calcium intakes with stroke occurrence. METHODS: A prospective cohort study was conducted among 36 094 participants aged 21 to 70 years. Dietary intake was assessed with a food frequency questionnaire. RESULTS: During 12 years of follow-up, 631 strokes occurred. After adjustment for confounders, magnesium intake was associated with reduced stroke risk (hazard ratio [95% confidence interval] per 100 mg/d, 0.80 [0.67-0.97] dietary magnesium; 0.78 [0.65-0.93] total magnesium). Potassium and calcium intakes were not associated with stroke. CONCLUSIONS: This study supports an association between high magnesium intake and a reduced stroke risk.
BACKGROUND AND PURPOSE: We aimed to investigate the associations of dietary and total potassium, magnesium, and calcium intakes with stroke occurrence. METHODS: A prospective cohort study was conducted among 36 094 participants aged 21 to 70 years. Dietary intake was assessed with a food frequency questionnaire. RESULTS: During 12 years of follow-up, 631 strokes occurred. After adjustment for confounders, magnesium intake was associated with reduced stroke risk (hazard ratio [95% confidence interval] per 100 mg/d, 0.80 [0.67-0.97] dietary magnesium; 0.78 [0.65-0.93] total magnesium). Potassium and calcium intakes were not associated with stroke. CONCLUSIONS: This study supports an association between high magnesium intake and a reduced stroke risk.
Authors: Arjun Seth; Yasmin Mossavar-Rahmani; Victor Kamensky; Brian Silver; Kamakshi Lakshminarayan; Ross Prentice; Linda Van Horn; Sylvia Wassertheil-Smoller Journal: Stroke Date: 2014-09-04 Impact factor: 7.914