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Literature DB >> 2450787

Regional distant sequence homology between amylases, alpha-glucosidases and transglucanosylases.

Abstract

Amylases possess short, conserved regions near functional side chains. Sequence comparison extends this relationship to comprise a maltase and a cyclodextrin glucanotransferase. Similarity also exists with intestinal sucrase-isomaltase and fungal glucoamylase near identified essential carboxyl groups. Homology between COOH-terminal regions of glucoamylase and cyclodextrin glucanotranserase may indicate raw-starch binding areas. It is suggested that amylases, alpha-glucosidases, and transglucanosylases acting on 1,4- and 1,6-alpha-glucosidic linkages share key structural features in the active centres.

Entities: Chemical Gene

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Year: 1988 PMID： 2450787 DOI： 10.1016/0014-5793(88)80644-6

Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124

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Cited

32 in total

1. Cloning of a rat kidney cDNA that stimulates dibasic and neutral amino acid transport and has sequence similarity to glucosidases.

Authors: R G Wells; M A Hediger
Journal: Proc Natl Acad Sci U S A Date: 1992-06-15 Impact factor: 11.205

2. Expression cloning of a cDNA from rabbit kidney cortex that induces a single transport system for cystine and dibasic and neutral amino acids.

Authors: J Bertran; A Werner; M L Moore; G Stange; D Markovich; J Biber; X Testar; A Zorzano; M Palacin; H Murer
Journal: Proc Natl Acad Sci U S A Date: 1992-06-15 Impact factor: 11.205

3. A super-secondary structure predicted to be common to several alpha-1,4-D-glucan-cleaving enzymes.

Authors: E A MacGregor; B Svensson
Journal: Biochem J Date: 1989-04-01 Impact factor: 3.857

4. Comparison of the domain-level organization of starch hydrolases and related enzymes.

Authors: H M Jespersen; E A MacGregor; M R Sierks; B Svensson
Journal: Biochem J Date: 1991-11-15 Impact factor: 3.857

5. A classification of glycosyl hydrolases based on amino acid sequence similarities.

Authors: B Henrissat
Journal: Biochem J Date: 1991-12-01 Impact factor: 3.857

6. Cloning and expression analysis of a potato cDNA that encodes branching enzyme: evidence for co-expression of starch biosynthetic genes.

Authors: J Kossmann; R G Visser; B Müller-Röber; L Willmitzer; U Sonnewald
Journal: Mol Gen Genet Date: 1991-11

Regional distant sequence homology between amylases, alpha-glucosidases and transglucanosylases.

1. Cloning of a rat kidney cDNA that stimulates dibasic and neutral amino acid transport and has sequence similarity to glucosidases.

2. Expression cloning of a cDNA from rabbit kidney cortex that induces a single transport system for cystine and dibasic and neutral amino acids.

3. A super-secondary structure predicted to be common to several alpha-1,4-D-glucan-cleaving enzymes.

4. Comparison of the domain-level organization of starch hydrolases and related enzymes.

5. A classification of glycosyl hydrolases based on amino acid sequence similarities.

6. Cloning and expression analysis of a potato cDNA that encodes branching enzyme: evidence for co-expression of starch biosynthetic genes.

7. Crystallization and preliminary X-ray analysis of isomaltase from Saccharomyces cerevisiae.

8. A zinc finger protein from Candida albicans is involved in sucrose utilization.

9. Regional sequence homologies in starch-degrading enzymes.

10. Antibodies against active-site peptides common to glucosyltransferases of mutans streptococci.