Literature DB >> 2450776

Preferential cytotoxicity on tumor cells by caffeic acid phenethyl ester isolated from propolis.

D Grunberger1, R Banerjee, K Eisinger, E M Oltz, L Efros, M Caldwell, V Estevez, K Nakanishi.   

Abstract

The honeybee hive product, propolis, is a folk medicine employed for treating various ailments. Many important pharmaceutical properties have been ascribed to propolis, including anti-inflammatory, antiviral, immunostimulatory and carcinostatic activities. Propolis extracts have provided an active component identified as caffeic acid phenethyl ester (CAPE), which was readily prepared in one step. Differential cytotoxicity has been observed in normal rat/human versus transformed rat/human melanoma and breast carcinoma cell lines in the presence of CAPE.

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Year:  1988        PMID： 2450776     DOI： 10.1007/bf01941717

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  5 in total

1.  In vitro studies on the cytostatic activity of propolis extracts.

Authors:  B Hladoń; W Bylka; M Ellnain-Wojtaszek; L Skrzypczak; P Szafarek; A Chodera; Z Kowalewski
Journal:  Arzneimittelforschung       Date:  1980

2.  Analysis of type 5 adenovirus transformation with a cloned rat embryo cell line (CREF).

Authors:  P B Fisher; L E Babiss; I B Weinstein; H S Ginsberg
Journal:  Proc Natl Acad Sci U S A       Date:  1982-06       Impact factor: 11.205

3.  Examination of the chemical composition of propolis I. Isolation and identification of the 3,4-dihydroxycinnamic acid (caffeic acid) from propolis.

Authors:  J Cizmárik; I Matel
Journal:  Experientia       Date:  1970

4.  Growth regulation of human melanocytes: mitogenic factors in extracts of melanoma, astrocytoma, and fibroblast cell lines.

Authors:  M Eisinger; O Marko; S Ogata; L J Old
Journal:  Science       Date:  1985-09-06       Impact factor: 47.728

5.  Caffeic acid is a selective inhibitor for leukotriene biosynthesis.

Authors:  Y Koshihara; T Neichi; S Murota; A Lao; Y Fujimoto; T Tatsuno
Journal:  Biochim Biophys Acta       Date:  1984-01-17
  5 in total
  64 in total

1.  Effect of the water extracts of propolis on stimulation and inhibition of different cells.

Authors:  Mohsen Fathi Najafi; Fatemeh Vahedy; Mohammad Seyyedin; Hamid Reza Jomehzadeh; Kazem Bozary
Journal:  Cytotechnology       Date:  2007-04-11       Impact factor: 2.058

2.  Effects of caffeic acid phenethyl ester (CAPE) on hepatopulmonary syndrome.

Authors:  Ahmet Tekin; Serdar Türkyılmaz; Tevfik Küçükkartallar; Murat Cakır; Hüseyin Yılmaz; Hasan Esen; Burhan Ateş; Ilhan Ciftci; Adil Kartal
Journal:  Inflammation       Date:  2011-12       Impact factor: 4.092

3.  Comparative effect of propolis of honey bee and some herbal extracts on Candida albicans.

Authors:  Shahin Gavanji; Behrouz Larki
Journal:  Chin J Integr Med       Date:  2015-07-07       Impact factor: 1.978

4.  Activity of caffeic acid phenethyl ester in Caenorhabditis elegans.

Authors:  Jeffrey J Coleman; Tomomi Komura; Julia Munro; Michael P Wu; Rakhee R Busanelli; Angela N Koehler; Méryl Thomas; Florence F Wagner; Edward B Holson; Eleftherios Mylonakis
Journal:  Future Med Chem       Date:  2016-10-14       Impact factor: 3.808

5.  Caffeic acid phenethyl ester (CAPE), derived from a honeybee product propolis, exhibits a diversity of anti-tumor effects in pre-clinical models of human breast cancer.

Authors:  Jing Wu; Coral Omene; Jerzy Karkoszka; Maarten Bosland; Jonathan Eckard; Catherine B Klein; Krystyna Frenkel
Journal:  Cancer Lett       Date:  2011-05-13       Impact factor: 8.679

Review 6.  Phenylpropanoids in radioregulation: double edged sword.

Authors:  Wanyeon Kim; Ki Moon Seong; BuHyun Youn
Journal:  Exp Mol Med       Date:  2011-06-30       Impact factor: 8.718

7.  An approach to the study of gene expression in hepatocarcinogenesis initiation.

Authors:  Olga Beltràn-Ramírez; Sergueï Sokol; Véronique Le-Berre; Jean M François; Saúl Villa-Treviño
Journal:  Transl Oncol       Date:  2010-04       Impact factor: 4.243

8.  Icariin, Formononetin and Caffeic Acid Phenethyl Ester Inhibit Feline Calicivirus Replication In Vitro.

Authors:  Zhanding Cui; Qian Wang; Dengliang Li; Shihui Zhao; Qian Zhang; Yuxin Tan; Qianwen Gong; Ting Liu; Jiang Shao; Shuang Zhang; Hailong Huang; Junzheng Wang; Zhihua Pei; Hao Dong; Kai Wang; Guixue Hu; Zhiyong Li
Journal:  Arch Virol       Date:  2021-06-25       Impact factor: 2.574

9.  Caffeic acid phenethyl ester induces adrenoleukodystrophy (Abcd2) gene in human X-ALD fibroblasts and inhibits the proinflammatory response in Abcd1/2 silenced mouse primary astrocytes.

Authors:  Jaspreet Singh; Mushfiquddin Khan; Inderjit Singh
Journal:  Biochim Biophys Acta       Date:  2013-01-11

10.  Inhibitors of human immunodeficiency virus integrase.

Authors:  M R Fesen; K W Kohn; F Leteurtre; Y Pommier
Journal:  Proc Natl Acad Sci U S A       Date:  1993-03-15       Impact factor: 11.205
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