Literature DB >> 7192990

In vitro studies on the cytostatic activity of propolis extracts.

B Hladoń, W Bylka, M Ellnain-Wojtaszek, L Skrzypczak, P Szafarek, A Chodera, Z Kowalewski.   

Abstract

Extracts from propolis have been investigated for cytostatic activity in vitro, by method of tissue culture on human KB and HeLa cell lines. Diethyl ether extract (DEEP) sowed the greatest activity and therefore it was further fractionated. Secondary DEEP fractions obtained by extraction with BuOH (ED50 = 2.6 micrograms/ml) and AcOEt (ED50 = 3.3 micrograms/ml) have been qualified to further in vivo studies.

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Year:  1980        PMID： 7192990

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN： 0004-4172


  3 in total

1.  Caffeic acid phenethyl ester induces mitochondria-mediated apoptosis in human myeloid leukemia U937 cells.

Authors:  Un-Ho Jin; Kwon-Ho Song; Muneo Motomura; Ikukatsu Suzuki; Yeun-Hwa Gu; Yun-Jeong Kang; Tae-Chul Moon; Cheorl-Ho Kim
Journal:  Mol Cell Biochem       Date:  2007-11-30       Impact factor: 3.396

2.  Preferential cytotoxicity on tumor cells by caffeic acid phenethyl ester isolated from propolis.

Authors:  D Grunberger; R Banerjee; K Eisinger; E M Oltz; L Efros; M Caldwell; V Estevez; K Nakanishi
Journal:  Experientia       Date:  1988-03-15

3.  Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B.

Authors:  K Natarajan; S Singh; T R Burke; D Grunberger; B B Aggarwal
Journal:  Proc Natl Acad Sci U S A       Date:  1996-08-20       Impact factor: 11.205
  3 in total

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