Francisco Mardones1, Pilar Arnaiz2, Salesa Barja2, Carolina Giadach3, Luis Villarroel4, Angelica Domínguez4, Oscar Castillo5, Marcelo Farias6. 1. División de Salud Pública. Facultad de Medicina. Pontificia Universidad Católica de Chile. Santiago. Chile.. mardones@med.puc.cl. 2. División de Pediatría. Facultad de Medicina. Pontificia Universidad Católica de Chile. Santiago. Chile.. 3. División de Nutrición. Facultad de Medicina. Pontificia Universidad Católica de Chile. Santiago. Chile.. 4. División de Salud Pública. Facultad de Medicina. Pontificia Universidad Católica de Chile. Santiago. Chile.. 5. Carrera de Nutrición y Dietética. Facultad de Medicina. Pontificia Universidad Católica de Chile. Santiago. Chile.. 6. División de Obstetricia y Ginecología. Facultad de Medicina. Pontificia Universidad Católica de Chile. Santiago. Chile..
Abstract
BACKGROUND: The origin of most non-communicable diseases (NCDs) is in early life. Consequently obtaining information on risk factors for NCDs is important for preventive purposes. However, there is no information available on the prevalence of obesity, metabolic syndrome (MS) and insulin resistance (IR) in Chilean children. OBJETIVES: To determine the prevalence of nutritional status, MS and IR, and secondly, to study the associations among them. METHODS: Cross-sectional study conducted during 2009-2011 in 20 public schools of Puente Alto County, Santiago, Chile. Anthropometry, blood pressure and pubertal status were assessed. A blood sample was obtained for determination of lipids, blood glucose and insulin. Abnormal Homeostasis model assessment index (HOMA-IR) was based on a national standard. RESULTS: 3325 children had a mean age of 11.4 ± 1 years old (range 10-15 years). The prevalence of obesity, MS and IR was 16.1%, 7.3% and 25.9%, respectively. The prevalence of IR and MS was higher in obese children. MS and IR were strongly associated with an OR of 8.0 (95% CI= 5.9-10.7). Multivariate analysis showed that all MS components were associated to IR. CONCLUSIONS: There is a relatively high prevalence of risk factors in this sample of children. The strong positive association between nutritional status, IR and MS points out the need to early identify risk factors for NCDs allowing for prevention. Copyright AULA MEDICA EDICIONES 2013. Published by AULA MEDICA. All rights reserved.
BACKGROUND: The origin of most non-communicable diseases (NCDs) is in early life. Consequently obtaining information on risk factors for NCDs is important for preventive purposes. However, there is no information available on the prevalence of obesity, metabolic syndrome (MS) and insulin resistance (IR) in Chilean children. OBJETIVES: To determine the prevalence of nutritional status, MS and IR, and secondly, to study the associations among them. METHODS: Cross-sectional study conducted during 2009-2011 in 20 public schools of Puente Alto County, Santiago, Chile. Anthropometry, blood pressure and pubertal status were assessed. A blood sample was obtained for determination of lipids, blood glucose and insulin. Abnormal Homeostasis model assessment index (HOMA-IR) was based on a national standard. RESULTS: 3325 children had a mean age of 11.4 ± 1 years old (range 10-15 years). The prevalence of obesity, MS and IR was 16.1%, 7.3% and 25.9%, respectively. The prevalence of IR and MS was higher in obese children. MS and IR were strongly associated with an OR of 8.0 (95% CI= 5.9-10.7). Multivariate analysis showed that all MS components were associated to IR. CONCLUSIONS: There is a relatively high prevalence of risk factors in this sample of children. The strong positive association between nutritional status, IR and MS points out the need to early identify risk factors for NCDs allowing for prevention. Copyright AULA MEDICA EDICIONES 2013. Published by AULA MEDICA. All rights reserved.
Authors: Francisco Mardones; Pilar Arnaiz; Paz Pacheco; Angelica Dominguez; Luis Villarroel; Johan G Eriksson; Salesa Barja; Marcelo Farías; Oscar Castillo Journal: Biomed Res Int Date: 2014-06-15 Impact factor: 3.411
Authors: Jenny Peplies; Claudia Börnhorst; Kathrin Günther; Arno Fraterman; Paola Russo; Toomas Veidebaum; Michael Tornaritis; Stefaan De Henauw; Staffan Marild; Dénes Molnar; Luis A Moreno; Wolfgang Ahrens Journal: Int J Behav Nutr Phys Act Date: 2016-09-02 Impact factor: 6.457