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Literature DB >> 2450416

Effect of FK506 in experimental organ transplantation.

S Todo¹, N Murase, Y Ueda, L Podesta, P ChapChap, D Kahn, K Okuda, O Imventarza, A Casavilla, J Demetris.

Abstract

FK506 is the most potent immunosuppressive agent known. Its toxicity is substantial in dogs, minor in rats, and unknown in subhuman primates. In small doses that are nontoxic even in dogs, it can be used in synergistic combination with cyclosporine, steroids, and presumably in other drugs.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1988 PMID： 2450416 PMCID： PMC2965605

Source DB: PubMed Journal: Transplant Proc ISSN： 0041-1345 Impact factor: 1.066

5 in total

1. Effect of a new immunosuppressive agent, FK 506, on heterotopic cardiac allotransplantation in the rat.

Authors: T Ochiai; K Nakajima; M Nagata; T Suzuki; T Asano; T Uematsu; T Goto; S Hori; T Kenmochi; T Nakagoori
Journal: Transplant Proc Date: 1987-02 Impact factor: 1.066

2. IMMUNOSUPPRESSION WITH FR 900506 FOR CANINE KIDNEY AND LIVER TRANSPLANTATION.

Authors: S Todo; L Makowka; T Starzl
Journal: Surg Res Commun Date: 1987-01-01

3. IN VITRO IMMUNOSUPPRESSIVE EFFECTS OF FR 900506 ON HUMAN T LYMPHOCYTE ALLOACTIVATION.

Authors: A Zeevi; R Duquesnoy; G Eiras; S Todo; L Makowka; T Starzl
Journal: Surg Res Commun Date: 1987

4. THE IMMUNOSUPPRESSIVE EFFECTS OF FR 900506 IN RATS RECEIVING HETEROTOPIC CARDIAC ALLOGRAFTS.

Authors: P Lee; N Murase; S Todo; L Makowka; T Starzl
Journal: Surg Res Commun Date: 1987

5. Canine liver transplantation under Nva2-cyclosporine versus cyclosporine.

Authors: S Todo; K A Porter; I Kam; S Lynch; R Venkataramanan; A DeWolf; T E Starzl
Journal: Transplantation Date: 1986-03 Impact factor: 4.939

5 in total

11 in total

1. Acute hemodynamic effects of FK 506 during and after orthotopic liver transplantation.

Authors: Y Kang; M A Mazer; A M DeWolf; J J Fung; T Gasior; R Venkataramanan; T E Starzl
Journal: Transplant Proc Date: 1990-02 Impact factor: 1.066

2. The effect of FK 506 and CyA on the Lewis rat renal ischemia model.

Authors: M A Nalesnik; H S Lai; N Murase; S Todo; T E Starzl
Journal: Transplant Proc Date: 1990-02 Impact factor: 1.066

3. The effects of FK 506 on renal function after liver transplantation.

Authors: J McCauley; J Fung; A Jain; S Todo; T E Starzl
Journal: Transplant Proc Date: 1990-02 Impact factor: 1.066

4. FK506: the promise and the paradox.

Authors: D J White
Journal: Clin Exp Immunol Date: 1991-01 Impact factor: 4.330

5. Inhibition by FK506 of established lesions of collagen-induced arthritis in rats.

Authors: C Arita; T Hotokebuchi; H Miyahara; K Arai; Y Sugioka; N Kaibara
Journal: Clin Exp Immunol Date: 1990-12 Impact factor: 4.330

Review 6. Clinical Evaluation of Modified Release and Immediate Release Tacrolimus Formulations.

Authors: Simon Tremblay; Rita R Alloway
Journal: AAPS J Date: 2017-07-17 Impact factor: 4.009

7. New approaches in the use of cyclosporine: with particular reference to the liver.

Authors: T E Starzl
Journal: Transplant Proc Date: 1988-06 Impact factor: 1.066

8. Co-administration of ketoconazole and tacrolimus therapy: a transplanted rat model.

Authors: Alaa Sabry; Amgad El-Agroudy; Hussein Sheashaa; Samia Hawas; Fagr B El-Shahat; Nashwa Barakat
Journal: Int Urol Nephrol Date: 2006-12-07 Impact factor: 2.370

9. Cytotoxic effects of FK506 on human renal proximal tubule cells in culture.

Authors: M M Atcherson; A L Trifillis
Journal: In Vitro Cell Dev Biol Anim Date: 1994-09 Impact factor: 2.416

10. Co-administration of ketoconazole and tacrolimus therapy: a transplanted rat model.

Authors: Nashwa Barakat; Alaa Sabry; Amgad El-Agroudy; Samia Hawas; Mahmoud Abdel-Maboud; Mahasen A El-Shair; M A Ghoneim
Journal: Int Urol Nephrol Date: 2005 Impact factor: 2.266