Literature DB >> 2450031

Murine CD2 gene expression during fetal thymus ontogeny.

M J Owen1, E J Jenkinson, M H Brown, W A Sewell, G W Krissansen, M J Crumpton, J J Owen.   

Abstract

The expression of the murine CD2 gene and the interleukin 2 receptor IL2R has been investigated during fetal thymus ontogeny. CD2 mRNA was undetectable at embryonic day 14 but was readily detectable at day 15 of gestation. Surface IL2R expression was maximal at day 14 and was clearly detectable at day 13. These results indicate that IL2R expression precedes that of CD2 by at least 2 days.

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Year:  1988        PMID： 2450031     DOI： 10.1002/eji.1830180129

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN： 0014-2980            Impact factor:   5.532


  12 in total

1.  The L2a element is a mouse CD8 silencer that interacts with MAR-binding proteins SATB1 and CDP.

Authors:  Xin Yao; Hui Nie; Ingrid C Rojas; June V Harriss; Shanna D Maika; Paul D Gottlieb; Gary Rathbun; Philip W Tucker
Journal:  Mol Immunol       Date:  2010-09-29       Impact factor: 4.407

2.  Developmental control of lymphokine gene expression in fetal thymocytes during T-cell ontogeny.

Authors:  S R Carding; E J Jenkinson; R Kingston; A C Hayday; K Bottomly; J J Owen
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

3.  T cells from baxalpha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53.

Authors:  H J Brady; G S Salomons; R C Bobeldijk; A J Berns
Journal:  EMBO J       Date:  1996-03-15       Impact factor: 11.598

4.  Altered cytokine expression in T lymphocytes from human immunodeficiency virus Tat transgenic mice.

Authors:  H J Brady; D J Abraham; D J Pennington; C G Miles; S Jenkins; E A Dzierzak
Journal:  J Virol       Date:  1995-12       Impact factor: 5.103

5.  A 3' transcriptional enhancer regulates tissue-specific expression of the human CD2 gene.

Authors:  R A Lake; D Wotton; M J Owen
Journal:  EMBO J       Date:  1990-10       Impact factor: 11.598

6.  The structure of the human CD2 gene and its expression in transgenic mice.

Authors:  G Lang; D Wotton; M J Owen; W A Sewell; M H Brown; D Y Mason; M J Crumpton; D Kioussis
Journal:  EMBO J       Date:  1988-06       Impact factor: 11.598

7.  Identification of CD2-/CD3+ T cells in fetal human tissue.

Authors:  D Kabelitz; P Conradt
Journal:  J Exp Med       Date:  1988-11-01       Impact factor: 14.307

8.  A novel subset of CD2-, CD3/T cell receptor alpha/beta+ human peripheral blood T cells. Phenotypic and functional characterization of interleukin 2-dependent CD2-CD3+ T cell clones.

Authors:  D Kabelitz; P Conradt; S Schondelmaier; H Wagner; R Haars
Journal:  J Exp Med       Date:  1989-08-01       Impact factor: 14.307

9.  Development and function of T cells in mice with a disrupted CD2 gene.

Authors:  N Killeen; S G Stuart; D R Littman
Journal:  EMBO J       Date:  1992-12       Impact factor: 11.598

10.  An essential role for nuclear factor kappaB in promoting double positive thymocyte apoptosis.

Authors:  T Hettmann; J DiDonato; M Karin; J M Leiden
Journal:  J Exp Med       Date:  1999-01-04       Impact factor: 14.307
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