Literature DB >> 24498976

Triterpene biosynthesis in plants.

Ramesha Thimmappa1, Katrin Geisler, Thomas Louveau, Paul O'Maille, Anne Osbourn.   

Abstract

The triterpenes are one of the most numerous and diverse groups of plant natural products. They are complex molecules that are, for the most part, beyond the reach of chemical synthesis. Simple triterpenes are components of surface waxes and specialized membranes and may potentially act as signaling molecules, whereas complex glycosylated triterpenes (saponins) provide protection against pathogens and pests. Simple and conjugated triterpenes have a wide range of applications in the food, health, and industrial biotechnology sectors. Here, we review recent developments in the field of triterpene biosynthesis, give an overview of the genes and enzymes that have been identified to date, and discuss strategies for discovering new triterpene biosynthetic pathways.

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Year:  2014        PMID: 24498976     DOI: 10.1146/annurev-arplant-050312-120229

Source DB:  PubMed          Journal:  Annu Rev Plant Biol        ISSN: 1543-5008            Impact factor:   26.379


  145 in total

1.  Directed optimization of a newly identified squalene synthase from Mortierella alpine based on sequence truncation and site-directed mutagenesis.

Authors:  Di Huang; Yongpeng Yao; Hang Zhang; Zhu Mei; Ru Wang; Lu Feng; Bin Liu
Journal:  J Ind Microbiol Biotechnol       Date:  2015-08-15       Impact factor: 3.346

2.  Whole-genome sequencing provides insights into the genetic diversity and domestication of bitter gourd (Momordica spp.).

Authors:  Junjie Cui; Yan Yang; Shaobo Luo; Le Wang; Rukui Huang; Qingfang Wen; Xiaoxia Han; Nansheng Miao; Jiaowen Cheng; Ziji Liu; Changyuan Zhang; Chengcheng Feng; Haisheng Zhu; Jianwen Su; Xinjian Wan; Fang Hu; Yu Niu; Xiaoming Zheng; Yulan Yang; Dai Shan; Zhensheng Dong; Weiming He; Narinder P S Dhillon; Kailin Hu
Journal:  Hortic Res       Date:  2020-06-01       Impact factor: 6.793

Review 3.  Synthetic Botany.

Authors:  Christian R Boehm; Bernardo Pollak; Nuri Purswani; Nicola Patron; Jim Haseloff
Journal:  Cold Spring Harb Perspect Biol       Date:  2017-07-05       Impact factor: 10.005

Review 4.  Enzymatic Cascade Reactions in Biosynthesis.

Authors:  Christopher T Walsh; Bradley S Moore
Journal:  Angew Chem Int Ed Engl       Date:  2019-02-20       Impact factor: 15.336

5.  A conserved amino acid residue critical for product and substrate specificity in plant triterpene synthases.

Authors:  Melissa Salmon; Ramesha B Thimmappa; Robert E Minto; Rachel E Melton; Richard K Hughes; Paul E O'Maille; Andrew M Hemmings; Anne Osbourn
Journal:  Proc Natl Acad Sci U S A       Date:  2016-07-13       Impact factor: 11.205

Review 6.  Structural and Chemical Biology of Terpenoid Cyclases.

Authors:  David W Christianson
Journal:  Chem Rev       Date:  2017-08-25       Impact factor: 60.622

Review 7.  Plant Glandular Trichomes: Natural Cell Factories of High Biotechnological Interest.

Authors:  Alexandre Huchelmann; Marc Boutry; Charles Hachez
Journal:  Plant Physiol       Date:  2017-07-19       Impact factor: 8.340

8.  Unusual and Highly Bioactive Sesterterpenes Synthesized by Pleurotus ostreatus during Coculture with Trametes robiniophila Murr.

Authors:  Xiao-Ting Shen; Xu-Hua Mo; Li-Ping Zhu; Ling-Ling Tan; Feng-Yu Du; Qian-Wen Wang; Yuan-Ming Zhou; Xiao-Jie Yuan; Bin Qiao; Song Yang
Journal:  Appl Environ Microbiol       Date:  2019-07-01       Impact factor: 4.792

9.  An Unexpected Oxidosqualene Cyclase Active Site Architecture in the Iris tectorum Multifunctional α-Amyrin Synthase.

Authors:  Shidan Wu; Fan Zhang; Wenbo Xiong; István Molnár; Jincai Liang; Aijia Ji; Caixia Wang; Shengliang Wang; Zhongqiu Liu; Ruibo Wu; Lixin Duan
Journal:  ACS Catal       Date:  2020-08-04       Impact factor: 13.084

10.  De novo transcriptome sequencing facilitates genomic resource generation in Tinospora cordifolia.

Authors:  Rakesh Singh; Rajesh Kumar; Ajay Kumar Mahato; Ritu Paliwal; Amit Kumar Singh; Sundeep Kumar; Soma S Marla; Ashok Kumar; Nagendra K Singh
Journal:  Funct Integr Genomics       Date:  2016-07-27       Impact factor: 3.410

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