Literature DB >> 2448603

An altered form of pp60c-src is expressed primarily in the central nervous system.

J M Le Beau1, O D Wiestler, G Walter.   

Abstract

The expression of two forms of pp60c-src, pp60 and pp60+, was measured in the central nervous system (CNS) and the peripheral nervous system. Both forms were expressed in the CNS, whereas only pp60 was primarily detected in the peripheral nervous system. Our findings suggest that pp60+ may play a role in events important to the CNS.

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Year:  1987        PMID： 2448603      PMCID： PMC368082          DOI： 10.1128/mcb.7.11.4115-4117.1987

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  11 in total

1.  Localization of conserved and nonconserved epitopes within the Rous sarcoma virus-encoded src protein.

Authors:  S J Parsons; D J McCarley; V W Raymond; J T Parsons
Journal:  J Virol       Date:  1986-09       Impact factor: 5.103

2.  The expression in eukaryotes of a tyrosine kinase which is reactive with pp60v-src antibodies.

Authors:  M Schartl; A Barnekow
Journal:  Differentiation       Date:  1982       Impact factor: 3.880

3.  pp60c-src is expressed in human fetal and adult brain.

Authors:  J P Sorge; L K Sorge; P F Maness
Journal:  Am J Pathol       Date:  1985-04       Impact factor: 4.307

4.  Neurones express high levels of a structurally modified, activated form of pp60c-src.

Authors:  J S Brugge; P C Cotton; A E Queral; J N Barrett; D Nonner; R W Keane
Journal:  Nature       Date:  1985 Aug 8-14       Impact factor: 49.962

5.  Neural tissues express high levels of the cellular src gene product pp60c-src.

Authors:  P C Cotton; J S Brugge
Journal:  Mol Cell Biol       Date:  1983-06       Impact factor: 4.272

6.  pp60c-src is developmentally regulated in the neural retina.

Authors:  L K Sorge; B T Levy; P F Maness
Journal:  Cell       Date:  1984-02       Impact factor: 41.582

7.  pp60c-src in the developing cerebellum.

Authors:  D W Fults; A C Towle; J M Lauder; P F Maness
Journal:  Mol Cell Biol       Date:  1985-01       Impact factor: 4.272

8.  Increased pp60c-src tyrosyl kinase activity in human neuroblastomas is associated with amino-terminal tyrosine phosphorylation of the src gene product.

Authors:  J B Bolen; N Rosen; M A Israel
Journal:  Proc Natl Acad Sci U S A       Date:  1985-11       Impact factor: 11.205

9.  Expression of pp60c-src protein kinase in adult and fetal human tissue: high activities in some sarcomas and mammary carcinomas.

Authors:  C Jacobs; H Rübsamen
Journal:  Cancer Res       Date:  1983-04       Impact factor: 12.701

10.  Accumulation of c-src mRNA is developmentally regulated in embryonic neural retina.

Authors:  L Vardimon; L E Fox; A A Moscona
Journal:  Mol Cell Biol       Date:  1986-11       Impact factor: 4.272
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  9 in total

1.  Expression of the yes proto-oncogene in cerebellar Purkinje cells.

Authors:  M Sudol; C F Kuo; L Shigemitsu; A Alvarez-Buylla
Journal:  Mol Cell Biol       Date:  1989-10       Impact factor: 4.272

2.  Association of protein phosphatase 2A with polyoma virus medium tumor antigen.

Authors:  G Walter; R Ruediger; C Slaughter; M Mumby
Journal:  Proc Natl Acad Sci U S A       Date:  1990-04       Impact factor: 11.205

3.  Evolutionary expression of the neuronal form of the src protein in the brain.

Authors:  X M Yang; R Martinez; J Le Beau; O Wiestler; G Walter
Journal:  Proc Natl Acad Sci U S A       Date:  1989-06       Impact factor: 11.205

4.  Developmental expression of two forms of pp60c-src in mouse brain.

Authors:  O D Wiestler; G Walter
Journal:  Mol Cell Biol       Date:  1988-01       Impact factor: 4.272

5.  Brain-specific src oncogene mRNA mapped in rat brain by in situ hybridization.

Authors:  C A Ross; G E Wright; M D Resh; R C Pearson; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

6.  Analysis of cDNAs of the proto-oncogene c-src: heterogeneity in 5' exons and possible mechanism for the genesis of the 3' end of v-src.

Authors:  T Dorai; J B Levy; L Kang; J S Brugge; L H Wang
Journal:  Mol Cell Biol       Date:  1991-08       Impact factor: 4.272

7.  Early activation of endogenous pp60src kinase activity during neuronal differentiation of cultured human neuroblastoma cells.

Authors:  C Bjelfman; G Meyerson; C A Cartwright; K Mellström; U Hammerling; S Påhlman
Journal:  Mol Cell Biol       Date:  1990-01       Impact factor: 4.272

8.  Growth inhibition of newly established human glioma cell lines by leukemia inhibitory factor.

Authors:  H Halfter; J Kremerskothen; J Weber; U Hacker-Klom; A Barnekow; E B Ringelstein; F Stögbauer
Journal:  J Neurooncol       Date:  1998-08       Impact factor: 4.130

9.  c-src gene product in developing rat brain is enriched in nerve growth cone membranes.

Authors:  P F Maness; M Aubry; C G Shores; L Frame; K H Pfenninger
Journal:  Proc Natl Acad Sci U S A       Date:  1988-07       Impact factor: 11.205
  9 in total

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