Literature DB >> 24482162

Overview of skeletal repair (fracture healing and its assessment).

Elise F Morgan1, Anthony De Giacomo1, Louis C Gerstenfeld1.   

Abstract

The study of postnatal skeletal repair is of immense clinical interest. Optimal repair of skeletal tissue is necessary in all varieties of elective and reparative orthopedic surgical treatments. However, the repair of fractures is unique in this context in that fractures are one of the most common traumas that humans experience and are the end-point manifestation of osteoporosis, the most common chronic disease of aging. In the first part of this introduction the basic biology of fracture healing is presented. The second part discusses the primary methodological approaches that are used to examine repair of skeletal hard tissue and specific considerations for choosing among and implementing these approaches.

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Year:  2014        PMID: 24482162      PMCID: PMC4466121          DOI: 10.1007/978-1-62703-989-5_2

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  41 in total

1.  Method for automated cartilage histomorphometry.

Authors:  S W O'Driscoll; R G Marx; J S Fitzsimmons; D E Beaton
Journal:  Tissue Eng       Date:  1999-02

2.  A new bone vascular perfusion compound for the simultaneous analysis of bone and vasculature.

Authors:  Krista L Sider; Janice Song; John E Davies
Journal:  Microsc Res Tech       Date:  2010-07       Impact factor: 2.769

3.  MRT letter: Contrast-enhanced computed tomographic imaging of soft callus formation in fracture healing.

Authors:  Lauren Nicole Miller Hayward; Chantal Marie-Jeanne de Bakker; Hrvoje Lusic; Louis Charles Gerstenfeld; Mark W Grinstaff; Elise Feng-I Morgan
Journal:  Microsc Res Tech       Date:  2011-10-28       Impact factor: 2.769

4.  Does adult fracture repair recapitulate embryonic skeletal formation?

Authors:  C Ferguson; E Alpern; T Miclau; J A Helms
Journal:  Mech Dev       Date:  1999-09       Impact factor: 1.882

5.  Expression of osteoprotegerin, receptor activator of NF-kappaB ligand (osteoprotegerin ligand) and related proinflammatory cytokines during fracture healing.

Authors:  T Kon; T J Cho; T Aizawa; M Yamazaki; N Nooh; D Graves; L C Gerstenfeld; T A Einhorn
Journal:  J Bone Miner Res       Date:  2001-06       Impact factor: 6.741

6.  Quantitative measures for fracture healing: an in-vitro biomechanical study.

Authors:  A Foux; R C Black; H K Uhthoff
Journal:  J Biomech Eng       Date:  1990-11       Impact factor: 2.097

7.  Impaired angiogenesis, early callus formation, and late stage remodeling in fracture healing of osteopontin-deficient mice.

Authors:  Craig L Duvall; W Robert Taylor; Daiana Weiss; Abigail M Wojtowicz; Robert E Guldberg
Journal:  J Bone Miner Res       Date:  2007-02       Impact factor: 6.741

8.  Analysis of fracture healing by large-scale transcriptional profile identified temporal relationships between metalloproteinase and ADAMTS mRNA expression.

Authors:  Kevin Wang; Prashanth Vishwanath; Gabriel S Eichler; Maisa O Al-Sebaei; Cory M Edgar; Thomas A Einhorn; Temple F Smith; Louis C Gerstenfeld
Journal:  Matrix Biol       Date:  2006-03-06       Impact factor: 11.583

9.  A novel murine segmental femoral graft model.

Authors:  Prarop Tiyapatanaputi; Paul T Rubery; Jonathan Carmouche; Edward M Schwarz; Regis J O'keefe; Xinping Zhang
Journal:  J Orthop Res       Date:  2004-11       Impact factor: 3.494

10.  Impaired fracture healing in the absence of TNF-alpha signaling: the role of TNF-alpha in endochondral cartilage resorption.

Authors:  L C Gerstenfeld; T J Cho; T Kon; T Aizawa; A Tsay; J Fitch; G L Barnes; D T Graves; T A Einhorn
Journal:  J Bone Miner Res       Date:  2003-09       Impact factor: 6.741

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  15 in total

1.  Cell Mechanosensitivity is Enabled by the LINC Nuclear Complex.

Authors:  Gunes Uzer; Clinton T Rubin; Janet Rubin
Journal:  Curr Mol Biol Rep       Date:  2016-02-01

2.  A naturally derived small molecule NDSM253 inhibits IKK1 to suppress inflammation response and promote bone healing after fracture.

Authors:  Liqi Shen; Yun Xiao; Hui Xie; Hongbin Zhao; Tao Luo; Lin Liu; Xuekun Pan
Journal:  Am J Transl Res       Date:  2021-01-15       Impact factor: 4.060

3.  Correlation between RUST assessments of fracture healing to structural and biomechanical properties.

Authors:  Margaret E Cooke; Amira I Hussein; Kyle E Lybrand; Alexander Wulff; Erin Simmons; Jeffrey H Choi; Jody Litrenta; William M Ricci; Jason W Nascone; Robert V O'Toole; Elise F Morgan; Louis C Gerstenfeld; Paul Tornetta
Journal:  J Orthop Res       Date:  2017-09-20       Impact factor: 3.494

4.  Outcomes of the Treatment of Fracture Non-union Using Combined Magnetic Field Bone Growth Stimulation: Experiences From a UK Trauma Unit.

Authors:  Vusumuzi Sibanda; Fitzgerald Anazor; Jai Relwani; Baljinder S Dhinsa
Journal:  Cureus       Date:  2022-05-18

5.  YAP and TAZ Promote Periosteal Osteoblast Precursor Expansion and Differentiation for Fracture Repair.

Authors:  Christopher D Kegelman; Madhura P Nijsure; Yasaman Moharrer; Hope B Pearson; James H Dawahare; Kelsey M Jordan; Ling Qin; Joel D Boerckel
Journal:  J Bone Miner Res       Date:  2020-10-07       Impact factor: 6.741

6.  VEGFA From Early Osteoblast Lineage Cells (Osterix+) Is Required in Mice for Fracture Healing.

Authors:  Evan G Buettmann; Jennifer A McKenzie; Nicole Migotsky; David Aw Sykes; Pei Hu; Susumu Yoneda; Matthew J Silva
Journal:  J Bone Miner Res       Date:  2019-08-01       Impact factor: 6.741

Review 7.  Gut microbial-derived short-chain fatty acids and bone: a potential role in fracture healing.

Authors:  A Wallimann; W Magrath; K Thompson; T Moriarty; R G Richards; C A Akdis; L O'Mahony; C J Hernandez
Journal:  Eur Cell Mater       Date:  2021-04-21       Impact factor: 4.325

8.  Osthole Promotes Bone Fracture Healing through Activation of BMP Signaling in Chondrocytes.

Authors:  Pinger Wang; Jun Ying; Cheng Luo; Xing Jin; Shanxing Zhang; Taotao Xu; Lei Zhang; Meng Mi; Di Chen; Peijian Tong; Hongting Jin
Journal:  Int J Biol Sci       Date:  2017-07-18       Impact factor: 6.580

9.  Effect of a Particulate and a Putty-Like Tricalcium Phosphate-Based Bone-grafting Material on Bone Formation, Volume Stability and Osteogenic Marker Expression after Bilateral Sinus Floor Augmentation in Humans.

Authors:  Christine Knabe; Doaa Adel-Khattab; Esther Kluk; Rainer Struck; Michael Stiller
Journal:  J Funct Biomater       Date:  2017-07-29

10.  Preclinical safety and efficacy of 24R,25-dihydroxyvitamin D3 or lactosylceramide treatment to enhance fracture repair.

Authors:  Corine Martineau; Martin Kaufmann; Alice Arabian; Glenville Jones; René St-Arnaud
Journal:  J Orthop Translat       Date:  2020-04-27       Impact factor: 5.191

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