Literature DB >> 35733483

Outcomes of the Treatment of Fracture Non-union Using Combined Magnetic Field Bone Growth Stimulation: Experiences From a UK Trauma Unit.

Vusumuzi Sibanda1, Fitzgerald Anazor1, Jai Relwani1, Baljinder S Dhinsa1.   

Abstract

INTRODUCTION: Fracture non-union is a distressing diagnosis for both patients and clinicians. Several methods have been tried to help promote bone healing. Some of the non-operative strategies include the use of pulsed ultrasound and electrical or magnetic bone stimulators. This study aimed at assessing the outcomes of patients treated with combined magnetic field (CMF) bone stimulators.
METHODS: All patients with confirmed fracture non-union treated using a CMF bone growth stimulator between May 2019 and December 2021 were included in the study. These were followed up at regular three-month intervals and monitored for signs of clinical and radiological union. The minimum patient follow-up was six months. Our primary outcome measure was union rates following CMF treatment. The secondary outcome measures were time to union and fracture type/configuration in relation to non-union.
RESULTS: A total of 29 patients were included. Of the patients, 52% were female. The average age of the patients was 53.42 years (SD: 17.66 years). Four were excluded because their follow-up period was less than six months. Patients were started on CMF bone growth stimulant treatment between four and 27 months from the initial fracture (mean: 11.56 months). The majority of the patients had tibial shaft (21%), distal femur (17%), ankle (10%) and distal humerus (10%) fractures. The overall success rate was 84% (n=21), with a mean time to union of 6.62 months.
CONCLUSION: Bone growth stimulators using combined magnetic fields are a viable treatment option for established fracture non-union. They can result in improved outcomes and can avoid risks and costs associated with surgical options to treat non-union. However, more studies need to be conducted to establish the efficacy of these methods conclusively.
Copyright © 2022, Sibanda et al.

Entities:  

Keywords:  bone healing; bone stimulators; combined magnetic field; electromagnetic stimulation; fracture healing; fracture non-union; fracture union

Year:  2022        PMID: 35733483      PMCID: PMC9205291          DOI: 10.7759/cureus.25100

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  13 in total

1.  The devastating effects of tibial nonunion on health-related quality of life.

Authors:  Mark R Brinker; Bryan D Hanus; Milan Sen; Daniel P O'Connor
Journal:  J Bone Joint Surg Am       Date:  2013-12-18       Impact factor: 5.284

2.  The biology of fracture healing.

Authors:  Richard Marsell; Thomas A Einhorn
Journal:  Injury       Date:  2011-04-13       Impact factor: 2.586

3.  Epidemiology of Fracture Nonunion in 18 Human Bones.

Authors:  Robert Zura; Ze Xiong; Thomas Einhorn; J Tracy Watson; Robert F Ostrum; Michael J Prayson; Gregory J Della Rocca; Samir Mehta; Todd McKinley; Zhe Wang; R Grant Steen
Journal:  JAMA Surg       Date:  2016-11-16       Impact factor: 14.766

Review 4.  Fracture healing: A review of clinical, imaging and laboratory diagnostic options.

Authors:  Brian P Cunningham; Sloane Brazina; Saam Morshed; Theodore Miclau
Journal:  Injury       Date:  2017-05-05       Impact factor: 2.586

5.  The Use of Combined Magnetic Field Treatment for Fracture Nonunions: A Prospective Observational Study.

Authors:  Mark Phillips; Jon Zoltan; Brad A Petrisor; Sheila Sprague; Judy Baumhauer
Journal:  J Long Term Eff Med Implants       Date:  2016

6.  Pulsed electromagnetic field stimulation for acute tibial shaft fractures: a multicenter, double-blind, randomized trial.

Authors:  Sam Adie; Ian A Harris; Justine M Naylor; Hamish Rae; Alan Dao; Sarah Yong; Victoria Ying
Journal:  J Bone Joint Surg Am       Date:  2011-09-07       Impact factor: 5.284

7.  Electrical stimulation for fracture healing: current evidence.

Authors:  Christina Goldstein; Sheila Sprague; Bradley A Petrisor
Journal:  J Orthop Trauma       Date:  2010-03       Impact factor: 2.512

8.  Fracture healing.

Authors:  R L Cruess; J Dumont
Journal:  Can J Surg       Date:  1975-09       Impact factor: 2.089

9.  Combined magnetic fields accelerate and increase spine fusion: a double-blind, randomized, placebo controlled study.

Authors:  Raymond J Linovitz; Mini Pathria; Mark Bernhardt; Daniel Green; Melvin D Law; Robert A McGuire; Pasquale X Montesano; Glen Rechtine; Richard M Salib; James T Ryaby; Joel S Faden; Regina Ponder; Larry R Muenz; Frank P Magee; Steven A Garfin
Journal:  Spine (Phila Pa 1976)       Date:  2002-07-01       Impact factor: 3.468

10.  Electrical stimulation for long-bone fracture-healing: a meta-analysis of randomized controlled trials.

Authors:  Brent Mollon; Vitor da Silva; Jason W Busse; Thomas A Einhorn; Mohit Bhandari
Journal:  J Bone Joint Surg Am       Date:  2008-11       Impact factor: 5.284

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