Literature DB >> 24471646

Bisphenol A and risk management ethics.

David B Resnik, Kevin C Elliott.   

Abstract

It is widely recognized that endocrine disrupting compounds, such as Bisphenol A, pose challenges for traditional paradigms in toxicology, insofar as these substances appear to have a wider range of low-dose effects than previously recognized. These compounds also pose challenges for ethics and policymaking. When a chemical does not have significant low-dose effects, regulators can allow it to be introduced into commerce or the environment, provided that procedures and rules are in place to keep exposures below an acceptable level. This option allows society to maximize the benefits from the use of the chemical while minimizing risks to human health or the environment, and it represents a compromise between competing values. When it is not possible to establish acceptable exposure levels for chemicals that pose significant health or environmental risks, the most reasonable options for risk management may be to enact either partial or complete bans on their use. These options create greater moral conflict than other risk management strategies, leaving policymakers difficult choices between competing values.
© 2014 John Wiley & Sons Ltd.

Entities:  

Keywords:  Bisphenol A; endocrine disruptors; ethics; low dose effects; regulation; risk management

Mesh:

Substances:

Year:  2014        PMID: 24471646      PMCID: PMC4115043          DOI: 10.1111/bioe.12079

Source DB:  PubMed          Journal:  Bioethics        ISSN: 0269-9702            Impact factor:   1.898


  27 in total

Review 1.  Mechanisms of chemical carcinogenesis and application to human cancer risk assessment.

Authors:  G M Williams
Journal:  Toxicology       Date:  2001-09-14       Impact factor: 4.221

Review 2.  Hormesis: U-shaped dose responses and their centrality in toxicology.

Authors:  E J Calabrese; L A Baldwin
Journal:  Trends Pharmacol Sci       Date:  2001-06       Impact factor: 14.819

Review 3.  Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses.

Authors:  Laura N Vandenberg; Theo Colborn; Tyrone B Hayes; Jerrold J Heindel; David R Jacobs; Duk-Hee Lee; Toshi Shioda; Ana M Soto; Frederick S vom Saal; Wade V Welshons; R Thomas Zoeller; John Peterson Myers
Journal:  Endocr Rev       Date:  2012-03-14       Impact factor: 19.871

4.  Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure.

Authors:  Frederick S vom Saal; Benson T Akingbemi; Scott M Belcher; Linda S Birnbaum; D Andrew Crain; Marcus Eriksen; Francesca Farabollini; Louis J Guillette; Russ Hauser; Jerrold J Heindel; Shuk-Mei Ho; Patricia A Hunt; Taisen Iguchi; Susan Jobling; Jun Kanno; Ruth A Keri; Karen E Knudsen; Hans Laufer; Gerald A LeBlanc; Michele Marcus; John A McLachlan; John Peterson Myers; Angel Nadal; Retha R Newbold; Nicolas Olea; Gail S Prins; Catherine A Richter; Beverly S Rubin; Carlos Sonnenschein; Ana M Soto; Chris E Talsness; John G Vandenbergh; Laura N Vandenberg; Debby R Walser-Kuntz; Cheryl S Watson; Wade V Welshons; Yelena Wetherill; R Thomas Zoeller
Journal:  Reprod Toxicol       Date:  2007-07-27       Impact factor: 3.143

5.  Associations between phthalate metabolite urinary concentrations and body size measures in New York City children.

Authors:  Susan L Teitelbaum; Nancy Mervish; Erin L Moshier; Nita Vangeepuram; Maida P Galvez; Antonia M Calafat; Manori J Silva; Barbara L Brenner; Mary S Wolff
Journal:  Environ Res       Date:  2012-01-04       Impact factor: 6.498

6.  Low-dose effects and nonmonotonic dose-responses of endocrine disrupting chemicals: has the case been made?

Authors:  Lorenz R Rhomberg; Julie E Goodman
Journal:  Regul Toxicol Pharmacol       Date:  2012-06-27       Impact factor: 3.271

7.  The precautionary principle: radiofrequency exposures from mobile telephones and base stations.

Authors:  Stelios A Zinelis
Journal:  Environ Health Perspect       Date:  2010-01       Impact factor: 9.031

8.  Chronic oral exposure to bisphenol A results in a nonmonotonic dose response in mammary carcinogenesis and metastasis in MMTV-erbB2 mice.

Authors:  Sarah Jenkins; Jun Wang; Isam Eltoum; Renee Desmond; Coral A Lamartiniere
Journal:  Environ Health Perspect       Date:  2011-10-12       Impact factor: 9.031

9.  Neurobehavioral function and low-level exposure to brominated flame retardants in adolescents: a cross-sectional study.

Authors:  Michał Kiciński; Mineke K Viaene; Elly Den Hond; Greet Schoeters; Adrian Covaci; Alin C Dirtu; Vera Nelen; Liesbeth Bruckers; Kim Croes; Isabelle Sioen; Willy Baeyens; Nicolas Van Larebeke; Tim S Nawrot
Journal:  Environ Health       Date:  2012-11-14       Impact factor: 5.984

Review 10.  Brominated flame retardants: cause for concern?

Authors:  Linda S Birnbaum; Daniele F Staskal
Journal:  Environ Health Perspect       Date:  2004-01       Impact factor: 9.031

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  5 in total

Review 1.  Bisphenol A exposure pathways in early childhood: Reviewing the need for improved risk assessment models.

Authors:  Bridget F Healy; Karin R English; Paul Jagals; Peter D Sly
Journal:  J Expo Sci Environ Epidemiol       Date:  2015-09-09       Impact factor: 5.563

2.  The Ethical Challenges of Socially Responsible Science.

Authors:  David B Resnik; Kevin C Elliott
Journal:  Account Res       Date:  2016       Impact factor: 2.622

3.  Values in environmental research: Citizens' views of scientists who acknowledge values.

Authors:  Kevin C Elliott; Aaron M McCright; Summer Allen; Thomas Dietz
Journal:  PLoS One       Date:  2017-10-25       Impact factor: 3.240

4.  Toxicological Risk Analysis in Data-Poor Countries: A Narrative Approach to Feed an "Awareness Raising-Community Empowerment" Vortex.

Authors:  Chiara Frazzoli
Journal:  Medicina (Kaunas)       Date:  2020-11-20       Impact factor: 2.430

5.  Estimated Dietary Bisphenol-A Exposure and Adiposity in Samoan Mothers and Children.

Authors:  Lacey W Heinsberg; Christina N N Bui; Jennifer C Hartle; Susan M Sereika; Courtney C Choy; Dongqing Wang; Christina Soti-Ulberg; Take Naseri; Muagututia Sefuiva Reupena; Rachel L Duckham; Jennifer J Park; Nicola L Hawley; Nicole C Deziel
Journal:  Toxics       Date:  2020-09-02
  5 in total

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